Month: November 2023

Uncategorized Published - 28 November, 2023    By - Dr Clemens
Clinical Performance of Decision Support Systems in Anesthesia, Intensive Care, and Emergency Medicine

AUTHORS: Harutyunyan, Robert MSc et al  Anesthesia & Analgesia 136(6):p 1084-1095, June 2023. BACKGROUND: Medical technology is expanding at an alarming rate, with its integration into health care often reflected by the constant evolution of best practices. This rapid expansion of available treatment modalities, when coupled with progressively increasing amounts of consequential data for health care […]

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Uncategorized Published - 28 November, 2023    By - Dr Clemens
Failure to Rescue and Mortality Differences After Appendectomy in a Low-Middle-Income Country and the United States

AUTHORS: Rosero, Eric B. MD, MSc et al  Anesthesia & Analgesia 136(6):p 1030-1038, June 2023. BACKGROUND: Major disparities in complications and mortality after appendectomy between countries with different income levels have not been well characterized, as comparative studies at patient level between countries are scant. This study aimed to investigate variations in postoperative complications, mortality, and […]

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Uncategorized Published - 28 November, 2023    By - Dr Clemens
Tracheostomy, Feeding-Tube, and In-Hospital Postoperative Mortality in Children

AUTHORS: Brown, Sydney E. S. MD, PhD et al  Anesthesia & Analgesia 136(6):p 1133-1142, June 2023. BACKGROUND: Neuromuscular/neurologic disease confers increased risk of perioperative mortality in children. Some patients require tracheostomy and/or feeding tubes to ameliorate upper airway obstruction or respiratory failure and reduce aspiration risk. Empiric differences between patients with and without these devices and […]

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Uncategorized Published - 28 November, 2023    By - Dr Clemens
Restricted Polypharmacy Compared to Usual Care in Mechanically Ventilated Patients

AUTHORS: Bose, Somnath MD, MPH, FASA et al  Anesthesia & Analgesia 136(6):p 1115-1121, June 2023. BACKGROUND: Adverse effects of excessive sedation in critically ill mechanically ventilated patients are well described. Although guidelines strongly recommend minimizing sedative use, additional agents are added as infusions, often empirically. The tradeoffs associated with such decisions remain unclear. METHODS: To test […]

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Uncategorized Published - 27 November, 2023    By - Dr Clemens
Transnasal Videoendoscopy for Preoperative Airway Risk Stratification: Development and Validation of a Multivariable Risk Prediction Model

AUTHORS: Barclay-Steuart, Alexander MD, MBA et al  Anesthesia & Analgesia 136(6):p 1164-1173, June 2023. BACKGROUND: Transnasal flexible videoendoscopy (TVE) of the larynx is a standard of care for the detection and staging of pharyngolaryngeal lesions in otorhinolaryngology. Patients frequently present with existing TVE examinations before anesthesia. Although these patients are considered high risk, the diagnostic value […]

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Uncategorized Published - 27 November, 2023    By - Dr Clemens
Direct Comparison of Peak Bulk Flow Rate of Programmable Intermittent Epidural Bolus and Manual Epidural Bolus Using a Closed-End Multiorifice Catheter

AUTHORS: Younger, Joshua D. MD et al  Anesthesia & Analgesia 136(6):p 1198-1205, June 2023. BACKGROUND: The programmable intermittent epidural bolus (PIEB) has been popularized as the optimal delivery technique for labor analgesia. Suggested advantages of this method are less local anesthetic consumption, improved maternal satisfaction, potentially shorter duration of labor, and decreased workload requirements for the […]

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Uncategorized Published - 27 November, 2023    By - Dr Clemens
Marijuana use linked to much higher risk of peripheral artery disease

Author: Michael Walter  Cardiovascular Business  Marijuana users are much more likely to have peripheral artery disease (PAD) than nonusers, according to new data presented Thursday, May 18, at the Society for Cardiovascular Angiography and Interventions (SCAI) 2023 Scientific Sessions. The study’s authors tracked data from the National Inpatient Sample, focusing on the years 2016 to 2019. After […]

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Uncategorized Published - 27 November, 2023    By - Dr Clemens
Racial/Ethnic Variability in Use of General Anesthesia for Pediatric Magnetic Resonance Imaging

AUTHORS: Gan, Ziyu BS et al  Anesthesia & Analgesia 136(6):p 1189-1197, June 2023. BACKGROUND: Children increasingly undergo diagnostic imaging procedures, sometimes with general anesthesia (GA). It is unknown whether the use of GA differs by race/ethnicity among children undergoing magnetic resonance imaging (MRI) scans. METHODS: This is a retrospective cohort study of GA use for pediatric […]

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Uncategorized Published - 27 November, 2023    By - Dr Clemens
Alfaxalone Alleviates Neurotoxicity and Cognitive Impairment Induced by Isoflurane Anesthesia in Offspring Rats

AUTHORS: Zhao, Xingkai MS et al  Anesthesia & Analgesia 136(6):p 1206-1216, June 2023. BACKGROUND: The anesthetic isoflurane can cause neurotoxicity in fetuses and offspring of rats, affecting their neurodevelopment. However, the underlying mechanisms and therapeutic targets of isoflurane-induced neurotoxicity remain to be identified. Alfaxalone (ALF) is a steroid anesthetic. Steroids have been reported to have neuroprotective […]

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Uncategorized Published - 24 November, 2023    By - Dr Clemens
Anesthetic Management and Deep Sedation After Emergence From General Anesthesia

AUTHORS: Deljou, Atousa MD et al  Anesthesia & Analgesia 136(6):p 1154-1163, June 2023. BACKGROUND: Residual deep sedation during anesthesia recovery may predict postoperative complications. We examined the incidence and risk factors for deep sedation after general anesthesia. METHODS: We retrospectively reviewed health records of adults who underwent procedures with general anesthesia and were admitted to the […]

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