Month: September 2023

Uncategorized Published - 29 September, 2023    By - Dr Clemens
Intraoperative Hypotension: How Do We Fare in Lower Risk Surgeries and How Can We Improve?

Author: Wael Saasouh, MD IARS Newsletter Issue 4 Intraoperative hypotension has been shown to negatively influence patient outcomes based on large trials from major academic centers. During the session, “A Pragmatic Discussion on Intraoperative Hypotension” on Saturday, April 15 at the IARS 2023 Annual Meeting, experts on this topic shared the results of similar work […]

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Uncategorized Published - 29 September, 2023    By - Dr Clemens
Association Between Profound Shock Signs and Peripheral Intravenous Access Success Rates in Trauma Patients in the Prehospital Scenario

AUTHORS: Barsky, Daniel MD et al  Anesthesia & Analgesia 136(5):p 934-940, May 2023. BACKGROUND: Hemorrhage is the leading cause of preventable death in trauma patients, and establishment of intravenous (IV) access is essential for volume resuscitation, a key component in the treatment of hemorrhagic shock. IV access among patients in shock is generally considered more challenging, […]

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Uncategorized Published - 29 September, 2023    By - Dr Clemens
Study of the Relationship Between Liver Function Markers and Traumatic Rhabdomyolysis: A Retrospective Study of Hemorrhagic Patients Admitted to Intensive Care Unit in a Level I Trauma Center

AUTHORS: Martinez, Thibault MD et al  Anesthesia & Analgesia 136(5):p 842-851, May 2023. BACKGROUND: Traumatic rhabdomyolysis (RM) is common and contributes to the development of medical complications, of which acute renal failure is the best described. Some authors have described an association between elevated aminotransferases and RM, suggesting the possibility of associated liver damage. Our study […]

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Uncategorized Published - 29 September, 2023    By - Dr Clemens
Ultramassive Transfusion for Trauma in the Age of Hemostatic Resuscitation

AUTHORS: Muldowney, Maeve MB, BCh, BAO et al  Anesthesia & Analgesia 136(5):p 927-933, May 2023. BACKGROUND: Uncontrolled bleeding is a leading cause of death in trauma. In the last 40 years, ultramassive transfusion (UMT; ≥20 units of red blood cells [RBCs]/24 hours) for trauma has been associated with 50% to 80% mortality; the question remains as […]

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Uncategorized Published - 29 September, 2023    By - Dr Clemens
Peripheral Intravenous Waveform Analysis Responsiveness to Subclinical Hemorrhage in a Rat Model

AUTHORS: Barajas, Matthew B. MD et al  Anesthesia & Analgesia 136(5):p 941-948, May 2023. BACKGROUND: Early detection and quantification of perioperative hemorrhage remains challenging. Peripheral intravenous waveform analysis (PIVA) is a novel method that uses a standard intravenous catheter to detect interval hemorrhage. We hypothesize that subclinical blood loss of 2% of the estimated blood volume […]

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Uncategorized Published - 28 September, 2023    By - Dr Clemens
In Vitro Analysis of Platelet Adhesion, Aggregation, and Surface GP1bα Expression in Stored Refrigerated Whole Blood

AUTHORS: Keneally, Ryan J. MD et al  Anesthesia & Analgesia 136(5):p 920-926, May 2023. BACKGROUND:  Warm, fresh whole blood (WB) has been used by the US military to treat casualties in Iraq and Afghanistan. Based on data in that setting, cold-stored WB has been used to treat hemorrhagic shock and severe bleeding in civilian trauma patients […]

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Uncategorized Published - 28 September, 2023    By - Dr Clemens
Peri-Intubation Hypoxia After Delayed Versus Rapid Sequence Intubation in Critically Injured Patients on Arrival to Trauma Triage

AUTHORS: Bandyopadhyay, Anjishnujit DM et al  Anesthesia & Analgesia 136(5):p 913-919, May 2023. BACKGROUND: Critically injured patients who are agitated and delirious on arrival do not allow optimal preoxygenation in the emergency area. We investigated whether the administration of intravenous (IV) ketamine 3 minutes before administration of a muscle relaxant is associated with better oxygen saturation […]

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Uncategorized Published - 28 September, 2023    By - Dr Clemens
Transnasal Videoendoscopy for Preoperative Airway Risk Stratification

AUTHORS: Barclay-Steuart, Alexander MD, MBA et al  Anesthesia & Analgesia 136(6):p 1164-1173, June 2023. | BACKGROUND: Transnasal flexible videoendoscopy (TVE) of the larynx is a standard of care for the detection and staging of pharyngolaryngeal lesions in otorhinolaryngology. Patients frequently present with existing TVE examinations before anesthesia. Although these patients are considered high risk, the diagnostic value […]

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Uncategorized Published - 28 September, 2023    By - Dr Clemens
Where are Anesthesia Healthcare Workers? Strained but Still Out and About

Author: Adaora M. Chima, MBBS, MPH IARS Newsletter Issue 4 Healthcare worker shortages are a growing problem on a global scale. Anesthesia care delivery has not escaped this phenomenon, a dilemma that was the focus of a panel session, “The Anesthesia Workforce: Who’s Doing the Work?” that closed out the IARS 2023 Annual Meeting on […]

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Uncategorized Published - 28 September, 2023    By - Dr Clemens
Association of Opioid Administration During General Anesthesia and Survival for Severely Injured Trauma Patients

AUTHORS: Levy, Dominique T. BS et al  Anesthesia & Analgesia 136(5):p 905-912, May 2023. BACKGROUND: There is a lack of reported clinical outcomes after opioid use in acute trauma patients undergoing anesthesia. Data from the Pragmatic, Randomized, Optimal Platelet and Plasma Ratios (PROPPR) study were analyzed to examine opioid dose and mortality. We hypothesized that higher […]

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