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AUTHORS: Böck, Carl et al European Journal of Anaesthesiology and Intensive Care 2(2):p e0020, April 2023. BACKGROUND In anaesthesiology, time domain parameters of the ECG are frequently used for long QT diagnosis, determination of branch blocks and for identifying atrioventricular blocks. However, this analysis depends on several factors and therefore the time domain parameters are prone […]
Read MoreAUTHORS: Stessel, Björn et al European Journal of Anaesthesiology 40(3):p 171-178, March 2023. BACKGROUND There is growing evidence that the analgesic effect of metamizole is mediated at least partly by central mechanisms, including the endocannabinoid/endovanilloid system. Consequently, metamizole may have additive or even synergistic analgesic effects with paracetamol and nonsteroidal anti-inflammatory drugs (NSAID). OBJECTIVE This study […]
Read MoreAUTHORS: Morrison-Nozik et al Journal of Head & Neck Anesthesia 6(2):p e42, December 2022. Abstract Stevens-Johnson syndrome (SJS), of which toxic epidermal necrolysis (TEN) is a more severe variant, is a cutaneous hypersensitivity reaction, usually triggered by certain prescribed medications. Airway management in SJS/TEN poses significant challenges, particularly when there is facial skin and oropharyngeal mucosal and/or laryngeal involvement. […]
Read MoreAuthor: Richard Simoneaux; Steven L. Shafer, MD, FASA, Editor-in-Chief ASA Monitor March 2023, Vol. 87, 1–6. We can’t get a break! Having battled SARS-CoV-2 for the past two years, the past few months have seen health care systems facing a “tridemic” comprising COVID, respiratory syncytial virus (RSV), and influenza. The national surge in RSV has been widely […]
Read MoreAuthors: Acharya, Mahip PhD et al The Clinical Journal of Pain 39(3):p 107-118, March 2023. Objective: To compare the safety profiles of low and high-dose tramadol, short-acting hydrocodone, and short-acting oxycodone therapies among chronic noncancer pain individuals. Materials and Methods: A retrospective cohort study of individuals with back/neck pain/osteoarthritis with an initial opioid prescription for tramadol, hydrocodone, or oxycodone was conducted using IQVIA PharMetrics […]
Read MoreAUTHORS: Belin, Olivier MD et al Anesthesia & Analgesia 136(3):p 540-550, March 2023. BACKGROUND: To counteract the vasoplegia induced by spinal anesthesia (SA) and maintain blood pressure (BP) during cesarean delivery, phenylephrine is currently recommended, but norepinephrine might offer superior preservation of cardiac output. We aimed to compare the hemodynamic effects of phenylephrine and norepinephrine administered […]
Read MoreAUTHORS: Brown, Sydney E. S. MD, PhD et al Anesthesia & Analgesia 136(6):p 1133-1142, June 2023. BACKGROUND: Neuromuscular/neurologic disease confers increased risk of perioperative mortality in children. Some patients require tracheostomy and/or feeding tubes to ameliorate upper airway obstruction or respiratory failure and reduce aspiration risk. Empiric differences between patients with and without these devices and […]
Read MoreAUTHORS: Guessous, K. MD et al Anesthesia & Analgesia April 03, 2023. BACKGROUND: Preoperative abnormal cognitive status is a risk factor for postoperative complications yet remains underdiagnosed. During propofol general anesthesia, intraoperative electroencephalography (EEG) variables, such as alpha band power (α-BP), correlate with cognitive status. This relationship under sevoflurane is unclear. We investigated whether […]
Read MoreAUTHORS: Jin, Sherry Y. FRCPC et al Anesthesia & Analgesia April 03, 2023. BACKGROUND: The incidence of failed spinal anesthesia varies widely in the obstetric literature. Although many risk factors have been suggested, their relative predictive value is unknown. The primary objective of this retrospective cohort study was to determine the incidence of failed spinal […]
Read MoreAUTHORS: Bose, Somnath MD, MPH, FASA et al Anesthesia & Analgesia 136(6):p 1115-1121, June 2023. BACKGROUND: Adverse effects of excessive sedation in critically ill mechanically ventilated patients are well described. Although guidelines strongly recommend minimizing sedative use, additional agents are added as infusions, often empirically. The tradeoffs associated with such decisions remain unclear. METHODS: To test […]
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