Month: July 2023

Uncategorized Published - 18 July, 2023    By - Dr Clemens
Brainstem modulation of nociception by periaqueductal gray neurons expressing the mu-opioid receptor in mice

Authors: Eileen Nguyen, MD, PhD et al  Anesthesiology June 2023. Background Pharmacological manipulations directed at the periaqueductal gray have demonstrated the importance of the mu-opioid receptor in modulating reflexive responses to nociception. We hypothesized that a supraspinal pathway centered on neurons in the periaqueductal gray containing the mu-opioid receptor could modulate nociceptive and itch behaviors. […]

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Uncategorized Published - 17 July, 2023    By - Dr Clemens
Sugammadex Is Not a Silver Bullet: Caveats Regarding Unmonitored Reversal

Authors: Michael M. Todd, M.D.; Aaron F. Kopman, M.D. Anesthesiology July 2023, Vol. 139, 1–3. “Their observations […] indicate that clinicians who do not see the necessity for quantitative or objective neuromuscular monitoring when reversing residual block with sugammadex need to rethink their position.” In the current issue of Anesthesiology, Bowdle et al. report the results of an observational […]

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Uncategorized Published - 17 July, 2023    By - Dr Clemens
Preoperative Evaluation in the 21st Century

Author: Jeanna D. Blitz, M.D., F.A.S.A., D.F.P.M. Anesthesiology July 2023, Vol. 139, 91–103. The preanesthesia evaluation is the process of clinical assessment that precedes the delivery of anesthesia care. It provides the foundation for creating the perioperative anesthesia and pain management plan.  The goal is to identify any factors that would prevent the patient from safely having […]

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Uncategorized Published - 17 July, 2023    By - Dr Clemens
A Dose-finding Study of Sugammadex for Reversal of Rocuronium in Cardiac Surgery Patients and Postoperative Monitoring for Recurrent Paralysis

Authors: T. Andrew Bowdle, M.D., Ph.D., F.A.S.E. et al  Anesthesiology July 2023, Vol. 139, 6–15. Background The dose of sugammadex recommended by the manufacturer for reversal of rocuronium is 2 mg/kg when the train-of-four count is 2 or more and 4 mg/kg when it is less than 2 but there is a posttetanic count of at least 1. […]

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Uncategorized Published - 17 July, 2023    By - Dr Clemens
Neuromuscular Monitoring: What’s New and Where Are We Headed?

Authors: Patrick Forrest, MD et al  ASA Monitor July 2023, Vol. 87, 1–5. Many readers may now be familiar with the new ASA practice guidelines for monitoring and antagonism of neuromuscular blockade that were published this past January (Anesthesiology 2023;138:13-41). For those who are not, this article may serve as a brief overview of the advances […]

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Uncategorized Published - 17 July, 2023    By - Dr Clemens
UpToDate®

ASA Monitor April 2023, Vol. 87, 17. UpToDate® and ASA Monitor are collaborating to present select content abstracts on “What’s New in Anesthesiology.” UpToDate is an evidence-based, clinical support resource used worldwide by health care practitioners to make decisions at the point of care. For complete, current “What’s New” content, or to become a subscriber for full content access, […]

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Uncategorized Published - 14 July, 2023    By - Dr Clemens
SEE Question

ASA Monitor July 2023, Vol. 87, 10. A 45-year-old woman is scheduled to undergo a bilateral mastectomy for metastatic breast cancer. According to a recent study of patients undergoing breast cancer surgery with general anesthesia maintained with propofol or volatile agents, which of the following MOST likely describes overall survival with use of propofol compared to […]

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Uncategorized Published - 14 July, 2023    By - Dr Clemens
ACE Question

ASA Monitor July 2023, Vol. 87, 7. Which of the following immunosuppressive drugs is MOST likely to cause renal dysfunction? □ (A) Tacrolimus □ (B) Mycophenolate mofetil □ (C) Basiliximab Immunosuppressant drugs are used to prevent or treat allograft rejection. Most of these drugs act during the induction phase of the immunological response, reducing lymphocyte proliferation. Some of them […]

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Uncategorized Published - 14 July, 2023    By - Dr Clemens
FTC Proposed Ban on Noncompetes: Implications for Your Practice

Authors: Judith Jurin Semo, JD; Shena J. Scott, MBA, FACMPE ASA Monitor July 2023, Vol. 87, 17–18. Restrictive covenants or noncompetes in employment are a contentious topic (ASA Monitor 2020;84:1-18). If a proposed rule issued in January 2023 by the Federal Trade Commission (FTC) is adopted, most employers in the United States will be foreclosed from requiring […]

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Uncategorized Published - 14 July, 2023    By - Dr Clemens
The Current and Future State of Anesthesiology: Good, Bad, or Indifferent?

Author: Zachary Deutch, MD, FASA ASA Monitor July 2023, Vol. 87, 13–15. The answer to the question in the title is rhetorical, as it will be in the eye of the beholder. Each ASA member has his or her own unique practice situation, personal disposition, and life priorities, so the realities one perceives as “bad” might […]

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