Month: May 2023

Uncategorized Published - 9 May, 2023    By - Dr Clemens
Acetaminophen Opioid Combinations and Liver Toxicity: Updated Data 2023

Author: Heidi Splete Practical Pain Management Volume 23 Issue 2 Hospitalizations for acute liver failure involving acetaminophen and opioid toxicity decreased significantly after the FDA mandated limiting acetaminophen to 325 mg in combination acetaminophen and opioid products over a decade ago. Previous research suggested that 40% to 58% of cases of acute liver failure (ALF) […]

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Uncategorized Published - 9 May, 2023    By - Dr Clemens
Promoting a Diverse Workforce in Academic Anesthesiology 2023

The Daily Dose Anesthesiology International Anesthesia Research Society Jane S. Moon, MD There is a pressing need to recruit, retain, and promote a diverse physician anesthesiologist workforce to encourage equity in healthcare delivery, as well as innovation and inclusivity in the workplace. This topic was the focus of “Diversity in Academic Anesthesiology: Enhancing the Workforce,” […]

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Uncategorized Published - 9 May, 2023    By - Dr Clemens
Shortages and Sustainability of the Anesthesia Workforce: What Does Cataract Surgery Have to Do With It? 2023

Author: Catherine L. Chen, MD, MPH ASA Monitor June 2023, Vol. 87, 37. When I received my first FAER Research Fellowship Grant to study unnecessary routine preoperative testing in Medicare cataract surgery patients as a CA-2 resident in 2013, I could not have predicted that I would still be studying the delivery of cataract surgery care […]

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Uncategorized Published - 8 May, 2023    By - Dr Clemens
A Dose-Finding Study of Sugammadex for Reversal of Rocuronium in Cardiac Surgery Patients and Postoperative Monitoring for Recurrent Paralysis 2023

Authors: Andrew Bowdle, MD, PhD, FASE et al Anesthesiology April 2023. Background The dose of sugammadex recommended by the manufacturer for reversal of rocuronium is 2 mg/kg when the train-of-four count is 2 or more and 4 mg/kg when it is less than 2 but there is a post-tetanic count of at least 1. The purpose of […]

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Uncategorized Published - 8 May, 2023    By - Dr Clemens
Ketamine: The Past, Present, and Potential Future of an Anesthetic Drug 2023

 Саrdiac Anesthesiologist  April 2023   Ketamine is a powerful anesthetic drug that has been used in medical settings for decades. However, its effects on the brain have also led to its use as a recreational drug, leading to controversy surrounding its use. Despite its negative associations, recent research has shown promising potential for the drug in the […]

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Uncategorized Published - 8 May, 2023    By - Dr Clemens
Hemostatic in vitro Properties of Novel Plasma Supernatants Produced from Late-Storage Low-Titer Type O Whole Blood 2023

Authors: Emily P. Mihalko, Ph.D et al  Anesthesiology April 2023. Background The use of low-titer group O whole blood is increasing. To reduce wastage, unused units can be converted to packed red blood cells. Supernatant is currently discarded post-conversion; however, it could be a valuable transfusable product. The aim of this study was to evaluate […]

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Uncategorized Published - 8 May, 2023    By - Dr Clemens
TREK-1 and TREK-2 knockout mice are not resistant to halothane or isoflurane 2023

Authors: Kira A Spencer, Ph.D. et al  Anesthesiology Newly Published on April 2023. Background. A variety of molecular targets for volatile anesthetics have been suggested including the anesthetic-sensitive K+ leak channel, TREK-1. Knockout of TREK-1 is reported to render mice resistant to volatile anesthetics, making TREK-1 channels compelling targets for anesthetic action. Spinal cord slices from mice, […]

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Uncategorized Published - 8 May, 2023    By - Dr Clemens
Measures of information content during anesthesia and emergence in the C. elegans nervous system 2023

Authors: Andrew S Chang, MS et al  Anesthesiology April 2023. Background Suppression of behavioral and physical responses defines the anesthetized state. This is accompanied, in humans, by characteristic changes in EEG patterns. However, these measures reveal little about the neuron or circuit-level physiological action of anesthetics, nor how information is trafficked between neurons. We assess […]

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Uncategorized Published - 5 May, 2023    By - Dr Clemens
Understanding Thrombolysis Contraindications: When Breaking Down Blood Clots May Not Be the Best Option” 2023

 Саrdiac Anesthesiologist  April 2023    Thrombolysis is a medical procedure that involves the use of medication to dissolve blood clots that have formed inside blood vessels. While thrombolysis can be an effective treatment option for certain conditions, there are certain situations where it may not be appropriate due to contraindications. A contraindication is a medical reason why […]

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Uncategorized Published - 5 May, 2023    By - Dr Clemens
Preserving Equity of Access in Times of Economic Stress 2023

Authors: Rhashedah A. Ekeoduru, MD et al  ASA Monitor April 2023, Vol. 87, 7–9. Health disparities are quantifiable differences in disease burden, morbidity, and mortality experienced by any socially disadvantaged group due to differences in access and quality of health care. Socioeconomic status, proximity to health care services, race, age, and gender contribute to health care […]

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