Month: March 2023

Uncategorized Published - 9 March, 2023    By - Dr Clemens
Incidence of Postreperfusion Hyperfibrinolysis in Liver Transplantation by Donor Type and Observed Treatment Strategies 2023

AUTHORS: Krom, Russell J. MD, PhD et al  Anesthesia & Analgesia 136(3):p 518-523, March 2023. BACKGROUND: Hyperfibrinolysis is a possible complication during liver transplantation, particularly immediately after reperfusion. METHODS: We performed a retrospective study to examine the incidence, treatment, and resolution of postreperfusion hyperfibrinolysis in patients undergoing liver transplantation at Duke University Hospital from 2015 to […]

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Uncategorized Published - 9 March, 2023    By - Dr Clemens
Complications and Technical Consideration of Ultrasound-Guided Rectus Sheath Blocks 2023

AUTHORS: Kwon, Hyun-Jung MD et al  Anesthesia & Analgesia 136(2):p 365-372, February 2023. BACKGROUND: Although the ultrasound-guided rectus sheath block (RSB) is usually regarded as an easy and safe procedure in clinical settings, there is currently no report on complications incidence. Therefore, the present study investigated complications in a large cohort and described the technical considerations […]

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Uncategorized Published - 9 March, 2023    By - Dr Clemens
Etomidate-Induced Myoclonus in Sprague-Dawley Rats Involves Neocortical Glutamate Accumulation and N-Methyl-d-Aspartate Receptor Activity 2023

AUTHORS: Feng, Yan MD et al  Anesthesia & Analgesia December 01, 2022. BACKGROUND: Etomidate-induced myoclonus, a seizure-like movement, is of interest to anesthetists. However, its origin in the brain and its underlying mechanism remain unclear. METHODS: Adult male Sprague-Dawley rats were anesthetized with etomidate, propofol, or lidocaine plus etomidate. We assessed the incidence of myoclonus, […]

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Uncategorized Published - 9 March, 2023    By - Dr Clemens
Predictors and Hospital Outcomes in Pregnant Patients Undergoing Extracorporeal Membrane Oxygenation 2023

AUTHORS: van den Bosch et al Anesthesia & Analgesia 135(6):p 1172-1179, December 2022 BACKGROUND: Extracorporeal membrane oxygenation (ECMO) is increasingly used in patients with severe cardiorespiratory collapse. Although prior large database reviews of ECMO use in the peripartum population exist, they do not stratify by ECMO indication nor do they include obstetric conditions such as preeclampsia. […]

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Uncategorized Published - 9 March, 2023    By - Dr Clemens
Arthroscopic Rotator Cuff Repair Performed with Intraarticular Tranexamic Acid. Could it Provide Improved Visual Clarity and less Postoperative Pain? 2023

DG Journal Club AUTHORS: Celaleddin Bildik, Tuna Pehlivanoglu J Shoulder Elbow Surg. 2022 Nov 17 BACKGROUND Tranexamic acid (TXA) was widely used in orthopedic surgery with the aim to reduce intra-/postoperative bleeding and bleeding related complications. The aim of the present study was to assess, whether intra-articular use of TXA during arthroscopic rotator cuff tear […]

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Uncategorized Published - 8 March, 2023    By - Dr Clemens
OCP002, a Mixed Agonist of Opioid and Cannabinoid Receptors, Produces Potent Antinociception With Minimized Side Effects 2023

AUTHORS: Xu, Biao PhD et al  Anesthesia & Analgesia 136(2):p 373-386, February 2023. BACKGROUND: Increasing attention has been attracted to the development of bifunctional compounds to minimize the side effects of opioid analgesics. Pharmacological studies have verified the functional interaction between opioid and cannabinoid systems in pain management, suggesting that coactivation of the opioid and cannabinoid […]

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Uncategorized Published - 8 March, 2023    By - Dr Clemens
Effect of Glutamine Administration After Cardiac Surgery on Kidney Damage in Patients at High Risk for Acute Kidney Injury 2023

AUTHORS: Weiss, Raphael MD et al  Anesthesia & Analgesia November 29, 2022. BACKGROUND: Acute kidney injury (AKI) is a common complication after cardiac surgery and is associated with increased morbidity and mortality. However, no specific treatment options are available, emphasizing the need for preventive measures. The aim of this study was to clarify the effect […]

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Uncategorized Published - 8 March, 2023    By - Dr Clemens
Understanding the Intricacies of Delivering Compassionate Care in the Intensive Care Unit and What Hinders It: A Qualitative Study of Members of 2 Critical Care Societies 2023

AUTHORS: Siddiqui, Shahla MD, MSc, FCCM et al  Anesthesia & Analgesia December 01, 2022. BACKGROUND: Patient-centered care is increasing in importance especially in the post-coronavirus disease 2019 (COVID-19) pandemic era. We sought to understand factors affecting compassionate care faced by intensivists in the intensive care unit (ICU). METHODS: Using survey methodology incorporating 3 real-life case vignettes, […]

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Uncategorized Published - 8 March, 2023    By - Dr Clemens
Regional anesthesia global health collaborations- a scoping review of current intervention methods 2023

Authors: Dohlman, Lena E et al  Current Opinion in Anaesthesiology 35(5):p 647-653, October 2022. Purpose of review  Perioperative anesthesia-related mortality is significantly higher in low-resource compared to high-resource countries. Regional anesthesia techniques can provide safety, cost, and access benefits when compared to general anesthesia in these settings but is underutilized primarily due to a lack of […]

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Uncategorized Published - 8 March, 2023    By - Dr Clemens
Usefulness of Inhaled Sedation in Patients With Severe ARDS Due to COVID-19 2023

DG Journal Club AUTHORS: Mario Gómez Duque, Ronald Medina, Cesar Enciso, Edgar Beltran Respir Care. 2022 Nov 22 BACKGROUND Sedation in intensive care is fundamental for optimizing clinical outcomes. For many years the world has been facing high rates of opioid use, and to combat the increasing opioid addiction plans at both national and international […]

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