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AUTHORS: Younger, Joshua D. MD et al Anesthesia & Analgesia: October 26, 2022 BACKGROUND: The programmable intermittent epidural bolus (PIEB) has been popularized as the optimal delivery technique for labor analgesia. Suggested advantages of this method are less local anesthetic consumption, improved maternal satisfaction, potentially shorter duration of labor, and decreased workload requirements for the anesthesia […]
Read MoreAUTHORS: Hofer, Ira S. MD et al Anesthesia & Analgesia: October 24, 2022 BACKGROUND: A single laboratory range for all individuals may fail to take into account underlying physiologic differences based on sex and genetic factors. We hypothesized that laboratory distributions differ based on self-reported sex and ethnicity and that ranges stratified by these factors better […]
Read MoreAUTHORS: Huang, Chanyan MD et al Anesthesia & Analgesia: October 24, 2022 BACKGROUND: Although sugammadex is well known for its use in reducing the incidence of residual neuromuscular blockade, this has not always been translated to improved clinical measures of postoperative respiratory muscle strength. Expiratory muscles play an important role in airway clearance and inspiratory muscle […]
Read MoreAUTHOR: Luedi, Markus M. MD, MBA Anesthesia & Analgesia: October 2022 – Volume 135 – Issue 4 – p 896-897 Life is not primarily a quest for pleasure, as [Sigmund] Freud believed, or a quest for power, as Alfred Adler taught, but a quest for meaning. The greatest task for any person is to find meaning […]
Read MoreAUTHORS: Gavilan, Eva MSN et al Anesthesia & Analgesia: October 24, 2022 Abstract The aim of this study was to evaluate the efficacy of presurgical interventions for promoting smoking cessation in terms of achieving smoking abstinence and reducing surgical complication rates. A systematic review of randomized clinical trials (RCTs) published from March 2009 to April 2021 […]
Read MoreAUTHORS: Belin, Olivier MD et al Anesthesia & Analgesia: October 24, 2022 BACKGROUND: To counteract the vasoplegia induced by spinal anesthesia (SA) and maintain blood pressure (BP) during cesarean delivery, phenylephrine is currently recommended, but norepinephrine might offer superior preservation of cardiac output. We aimed to compare the hemodynamic effects of phenylephrine and norepinephrine administered by […]
Read MoreAUTHORS: Wang, Jun-Wu BD et al Anesthesia & Analgesia: October 2022 – Volume 135 – Issue 4 – p 865-876 BACKGROUND: The number of patients with diabetic neuropathic pain (DNP) continues to increase, but available treatments are limited. This study aimed to examine the influence of reactive oxygen species (ROS)-thioredoxin-interacting protein (TXNIP)-NOD–like receptor protein 3 (NLRP3)-N-methyl-D-aspartic […]
Read MoreAUTHOR: Connor, Christopher W. MD, PhD Anesthesia & Analgesia: October 2022 – Volume 135 – Issue 4 – p 855-864 BACKGROUND: BIS (a brand of processed electroencephalogram [EEG] depth-of-anesthesia monitor) scores have become interwoven into clinical anesthesia care and research. Yet, the algorithms used by such monitors remain proprietary. We do not actually know what we […]
Read MoreAUTHORS: Tewfik, George L. MD et al Anesthesia & Analgesia: October 2022 – Volume 135 – Issue 4 – p 845-854 BACKGROUND: Many day-of-surgery cancellations are avoidable, and different strategies are used to prevent these costly adverse events. Despite these past analyses and evaluations of positive interventions, studies have not examined the final disposition of patients […]
Read MoreAUTHORS: Yang, Zhengbo MD et al Anesthesia & Analgesia: October 2022 – Volume 135 – Issue 4 – p 877-887 BACKGROUND: Sevoflurane (SEVO) increases neuronal excitation in neonatal rodent brains through alteration of gamma aminobutyric acid (GABA)(A) receptor signaling and increases corticosterone release. These actions may contribute to mechanisms that initiate the anesthetic’s long-term neuroendocrine and […]
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