Month: August 2022

Uncategorized Published - 31 August, 2022    By - Dr Clemens
Hospital-Acquired Infection, Length of Stay, and Readmission in Elective Surgery Patients Transfused 1 Unit of Red Blood Cells

AUTHORS: Trentino, Kevin M. PhD Anesthesia & Analgesia: September 2022 – Volume 135 – Issue 3 – p 586-591 BACKGROUND: Most patients transfused red blood cells in elective surgery receive small volumes of blood, which is likely to be discretionary and avoidable. We investigated the outcomes of patients who received a single unit of packed red […]

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Uncategorized Published - 31 August, 2022    By - Dr Clemens
Red Blood Cell Transfusion and Postoperative Infection in Patients Having Coronary Artery Bypass Grafting Surgery

AUTHORS: Mazzeffi, Michael A. MD, MPH, MSc, FASA et al  Anesthesia & Analgesia: September 2022 – Volume 135 – Issue 3 – p 558-566 BACKGROUND:  Coronary artery bypass grafting (CABG) is the most common cardiac surgical procedure in the world and up to one-third of patients are transfused red blood cells (RBCs). RBC transfusion may increase […]

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Uncategorized Published - 31 August, 2022    By - Dr Clemens
Effect of Etomidate vs Propofol for Total Intravenous Anesthesia on Major Postoperative Complications in Older Patients

DG Journal Club AUTHORS: Zhihong Lu et al JAMA Surg. 2022 Aug 10 Importance Older patients may benefit from the hemodynamic stability of etomidate for general anesthesia. However, it remains uncertain whether the potential for adrenocortical suppression with etomidate may increase morbidity. Objective To test the primary hypothesis that etomidate vs propofol for anesthesia does […]

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Uncategorized Published - 31 August, 2022    By - Dr Clemens
Anesthetic Management of a Patient With Arterial Tortuosity Syndrome Undergoing Cerebral Revascularization Surgery—A Case Report

Authors: Ajayan, Neeraja MD, DM A & A Practice: June 2022 – Volume 16 – Issue 6 Abstract Arterial tortuosity syndrome is a rare hereditary autosomal recessive connective tissue disorder characterized by elongation and tortuosity of the large- and medium-sized arteries. We present the case of a 13-year old child with arterial tortuosity syndrome who underwent […]

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Uncategorized Published - 31 August, 2022    By - Dr Clemens
Viscoelastic Testing and Factor Concentrate Therapy to Reduce Bleeding and Transfusions in the Surgical Separation of Ischiophagus Twins

Authors: Sarmiento, Ignacio A. MD et al  A & A Practice: June 2022 – Volume 16 – Issue 6 – p e01594 Abstract The surgical procedure to separate conjoined twins represents a rare and major challenge. One of the most feared perioperative scenarios is the presence of coagulopathy secondary to bleeding. We present a case of […]

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Uncategorized Published - 30 August, 2022    By - Dr Clemens
A Contemporary Analysis of Phlebotomy and Iatrogenic Anemia Development Throughout Hospitalization in Critically Ill Adults

Authors: Matzek, Luke J. MD et al  Anesthesia & Analgesia: September 2022 – Volume 135 – Issue 3 – p 501-510 Abstract BACKGROUND: Anemia is common in critically ill patients and may be exacerbated through phlebotomy-associated iatrogenic blood loss. Differences in phlebotomy practice across patient demographic characteristics, clinical features, and practice environments are unclear. This investigation […]

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Uncategorized Published - 30 August, 2022    By - Dr Clemens
Patient Blood Management Is a New Standard of Care to Optimize Blood Health

Author: Goobie, Susan M. MD, FRCPC Anesthesia & Analgesia: September 2022 – Volume 135 – Issue 3 – p 443-446 Patient blood management (PBM) encompasses all aspects of optimizing a patient’s blood health. Blood is the body’s liquid organ. Responsible for oxygen delivery, blood has many functions, including maintaining the delicate balance between hemostasis and […]

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Uncategorized Published - 30 August, 2022    By - Dr Clemens
Carbon Dioxide, Blood Pressure, and Perioperative Stroke

DG Journal Club AUTHORS: Phillip E Vlisides et al Anesthesiology. 2022 Aug 12 BACKGROUND The relationship between intraoperative physiology and postoperative stroke is incompletely understood. Preliminary data suggest that either hypo- or hypercapnia coupled with reduced cerebrovascular inflow (e.g., due to hypotension) can lead to ischemia. This study tested the hypothesis that the combination of […]

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Uncategorized Published - 30 August, 2022    By - Dr Clemens
Perioperative Care of Patients Undergoing Major Complex Spinal Instrumentation Surgery: Clinical Practice Guidelines From the Society for Neuroscience in Anesthesiology and Critical Care

Authors: Blacker, Samuel N. MD, FASA et al  Journal of Neurosurgical Anesthesiology: July 2022 – Volume 34 – Issue 3 – p 257-276 Abstract Evidence-based standardization of the perioperative management of patients undergoing complex spine surgery can improve outcomes such as enhanced patient satisfaction, reduced intensive care and hospital length of stay, and reduced costs. The […]

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Uncategorized Published - 30 August, 2022    By - Dr Clemens
Estimates of Probabilities of Successful Development of Pain Medications: An Analysis of Pharmaceutical Clinical Development Programs from 2000 to 2020

Authors: Dermot P. Maher, M.D., M.S., M.H.S. et al  Anesthesiology August 2022, Vol. 137, 243–251. Background The authors estimate the probability of successful development and duration of clinical trials for medications to treat neuropathic and nociceptive pain. The authors also consider the effect of the perceived abuse potential of the medication on these variables. Methods This […]

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