Month: July 2022

Uncategorized Published - 15 July, 2022    By - Dr Clemens
Anesthesia Pain and Safety Considerations in Cancer Patients

Authors: Dylan Irvine, BScH; Jeffrey Huang, MD Anesthesia Patient Safety Foundation Volume 37, No. 2 June 2022  Introduction The subspeciality of onco-anesthesia has gradually gained traction over the past few years. In addition to the comorbid diseases that some cancer patients present with, the interactions and consequences of their antineoplastic regimens must also be considered […]

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Uncategorized Published - 15 July, 2022    By - Dr Clemens
Does pollution cause migraine attacks?

Author: Morgan Meissner PhD MedicalNewsToday Stress, hormonal changes, and certain types of foods can all trigger migraine attacks. Some people with migraine find that environmental conditions, including air quality, also affect their symptoms. For people living with migraine, identifying triggers that cause migraine episodes can be a helpful way to minimize the disruptive nature of […]

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Uncategorized Published - 15 July, 2022    By - Dr Clemens
Desflurane and remifentanil anesthesia in a child with citrin deficiency

A case report Authors: Kim, Kanghui MD; Jung, Sung Mee MD, PhD∗ Editor(s): Saranathan., Maya Medicine: March 04, 2022 – Volume 101 – Issue 9 – p e28954 Rationale: Hyperammonemia, metabolic derangement, and/or the prolonged effects of anesthetics may lead to delayed emergence from general anesthesia as well as the onset of type 2 citrullinemia, even […]

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Uncategorized Published - 14 July, 2022    By - Dr Clemens
Perioperative Considerations of Cannabis Use on Anesthesia Administration

Authors: Dylan Irvine, BScH; Tricia Meyer, PharmD, MS; John Williams, MD; Jeffrey Huang, MD Anesthesia Pateitn Safety Foundation Volume 37, No. 2 June 2022  Introduction As of 2018, an estimated 9.5% of the United States adult population were cannabis users.1 This percentage has likely continued to increase with the use of both recreational and medicinal cannabis […]

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Uncategorized Published - 14 July, 2022    By - Dr Clemens
Estimates of Probabilities of Successful Development of Pain Medications

AUTHORS: Dermot P. Maher, M.D., M.S., M.H.S. et al  Anesthesiology June 2022. Background The authors estimate the probability of successful development and duration of clinical trials for medications to treat neuropathic and nociceptive pain. The authors also consider the effect of the perceived abuse potential of the medication on these variables. Methods This study uses […]

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Uncategorized Published - 14 July, 2022    By - Dr Clemens
Extracorporeal membrane oxygenation in coronavirus disease 2019

AUTHORS: Friedrichson, Benjamin et al  European Journal of Anaesthesiology: May 2022 – Volume 39 – Issue 5 – p 445-451 BACKGROUND In the context of the coronavirus disease 2019 (COVID-19) pandemic, many retrospective single-centre or specialised centre reports have shown promising mortality rates with the use of extracorporeal membrane oxygenation (ECMO) therapy. However, the mortality rate […]

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Uncategorized Published - 14 July, 2022    By - Dr Clemens
The Effect of Duloxetine on Mechanistic Pain Profiles, Cognitive Factors, and Clinical Pain in Patients with Painful Knee Osteoarthritis

AUTHORS: Kristian Kjaer-Staal Petersen et al Eur J Pain. 2022 May 31 BACKGROUND Duloxetine is indicated in the management of pain in osteoarthritis. Evidence suggests that duloxetine modulate central pain mechanisms and cognitive factors, and these factors are assumed contributing to the analgesic effect. This proof-of-mechanism, randomized, placebo-controlled, crossover, double-blinded trial evaluated the effect of […]

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Uncategorized Published - 14 July, 2022    By - Dr Clemens
Off-Label Low-Flow Sevoflurane: Regulatory Red Herring or Liability Landmine?

Author: Brian Thomas, JD et al Anesthesia Patient Safety Foundation Volume 37, No. 2 June 2022  Administration of sevoflurane at low-flow rates remains a controversial practice due to the low-flow limits described in the Food and Drug Administration’s (FDA) required labeling. Specifically, the labeling in the United States requires no less than 1 L/min for […]

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Uncategorized Published - 13 July, 2022    By - Dr Clemens
Dexmedetomidine vs other sedatives in critically ill mechanically ventilated adults

Authors: Kimberley Lewis et al Intensive Care Med. 2022 Jun 1 Conventional gabaminergic sedatives such as benzodiazepines and propofol are commonly used in mechanically ventilated patients in the intensive care unit (ICU). Dexmedetomidine is an alternative sedative that may achieve lighter sedation, reduce delirium, and provide analgesia. Our objective was to perform a comprehensive systematic […]

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Uncategorized Published - 13 July, 2022    By - Dr Clemens
Patient Safety and Low-Flow Anesthesia

Authors: Jeffrey M. Feldman, MD, MSE; Samsun Lampotang, PhD, FSSH, FAIMBE Anesthesia Patient Safety Foundation Volume 37, No. 2  June 2022  The benefits of low-flow anesthesia are well established and include reduced inhaled anesthetic waste, decreased cost, and fewer greenhouse gas effects.1 For the individual patient, low-flow anesthesia reduces loss of heat and humidity from the […]

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