Month: July 2022

Uncategorized Published - 25 July, 2022    By - Dr Clemens
Dexmedetomidine Diminishes, but Does Not Prevent, Developmental Effects of Sevoflurane in Neonatal Rats

AUTHORS: Yang, Zhengbo MD et al  Anesthesia & Analgesia: June 21, 2022 BACKGROUND: Sevoflurane (SEVO) increases neuronal excitation in neonatal rodent brains through alteration of gamma aminobutyric acid (GABA)(A) receptor signaling and increases corticosterone release. These actions may contribute to mechanisms that initiate the anesthetic’s long-term neuroendocrine and neurobehavioral effects. Dexmedetomidine (DEX), a non-GABAergic α2-adrenergic receptor […]

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Uncategorized Published - 25 July, 2022    By - Dr Clemens
The Specialist Anesthesiology Workforce in East, Central, and Southern Africa

AUTHORS: Asingei, Juventine MPH et al  Anesthesia & Analgesia: June 22, 2022  BACKGROUND: The populations of the East, Central, and Southern African regions receive only a fraction of the surgical procedures they require, and patients are more likely to die after surgery than the global average. An insufficient anesthetic workforce is a key barrier to safe […]

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Uncategorized Published - 22 July, 2022    By - Dr Clemens
Spinal Anaesthesia Linked to Higher Opioid Use After Hip Fracture Surgery

DG News Spinal anaesthesia was associated with more pain in the first 24 hours after hip fracture surgery and more prescription analgesic use at 60 days compared with general anaesthesia, according to a study published in the Annals of Internal Medicine. “In our study, patients who got spinal anaesthesia did get fewer opioids in the operating […]

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Uncategorized Published - 22 July, 2022    By - Dr Clemens
How to use cayenne for shingles pain

Author: Beth Sisson MedicalNewsToday Cayenne contains a compound called capsaicin, which may help to relieve pain. Topical application of capsaicin may help to relieve shingles pain. Capsaicin is the compound in cayenne that gives it its spicy flavor and burning sensation. Capsaicin has pain-relieving properties that may help to reduce shingles pain. This article examines […]

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Uncategorized Published - 22 July, 2022    By - Dr Clemens
Onset and temporal sequencing patterns of comorbidity between lifetime major depression, panic disorder and fibromyalgia

DG Journal Club AUTHORS: Alessandra Alciati, Fabiola Atzeni, Fausto Salaffi, Piercarlo Sarzi-Puttini Clin Exp Rheumatol. 2022 Jun 13 OBJECTIVES Fibromyalgia (FM) is a syndrome of unknown aetiology characterised by chronic widespread musculoskeletal pain and associated with high rates of psychiatric comorbidities, mainly mood and anxiety disorders.This study aims to determine the age at onset (AAO) […]

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Uncategorized Published - 22 July, 2022    By - Dr Clemens
Large study suggests shingles does not increase the risk of dementia

Author: Ferdinand Lali PhD MedicalNewsToday Herpes zoster, also known as shingles, is a common disease among older adults caused by the varicella-zoster virus that also causes chickenpox. Some previous studies have linked shingles to an increased risk of dementia, but others have reported a lack of such an association. A new large population-based study shows that […]

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Uncategorized Published - 22 July, 2022    By - Dr Clemens
Spinal Cord Stimulation Alleviates Neuropathic Pain by Attenuating Microglial Activation via Reducing Colony-Stimulating Factor 1 Levels in the Spinal Cord in a Rat Model of Chronic Constriction Injury

AUTHORS: Sun, Cong MD et al  Anesthesia & Analgesia: July 2022 – Volume 135 – Issue 1 – p 178-190 BACKGROUND: Spinal cord stimulation (SCS) is an emerging, minimally invasive procedure used to treat patients with intractable chronic pain conditions. Although several signaling pathways have been proposed to account for SCS-mediated pain relief, the precise mechanisms […]

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Uncategorized Published - 22 July, 2022    By - Dr Clemens
Causes of a throbbing headache at the back of the head

AUTHOR: Amanda Barrell MedicalNewsToday People can experience a range of headaches that can cause different types of pain, including a throbbing pain at the back of the head. This pain can result from a headache or other medical conditions. According to the National Institute of Neurological Disorders and Stroke (NINDS) headaches are among the most common […]

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Uncategorized Published - 21 July, 2022    By - Dr Clemens
Racial Disparities in the Use of Peripheral Nerve Blocks for Postoperative Analgesia After Total Mastectomy

AUTHOPRS: Mazzeffi, Michael A. MD, MPH, MSc et al  Anesthesia & Analgesia: July 2022 – Volume 135 – Issue 1 – p 170-177 BACKGROUND: Peripheral nerve blocks (PNBs) are used to provide postoperative analgesia after total mastectomy. PNBs improve patient satisfaction and decrease postoperative opioid use, nausea, and vomiting. Few studies have examined whether there is […]

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Uncategorized Published - 21 July, 2022    By - Dr Clemens
Machine Learning-Based Models Predicting Outpatient Surgery End Time and Recovery Room Discharge at an Ambulatory Surgery Center

AUTHORS: Gabriel, Rodney A. MD, MAS et al Anesthesia & Analgesia: July 2022 – Volume 135 – Issue 1 – p 159-169 BACKGROUND: Days before surgery, add-ons may be scheduled to fill unused surgical block time at an outpatient surgery center. At times, outpatient surgery centers have time limitations for end of block time and discharge […]

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