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ASA Monitor April 2022, Vol. 86, 22. Trends NIH-sponsored mix-and-match trial finds additional COVID-19 dose safe and immunogenic A new report published in The New England Journal of Medicine (N Engl J Med January 2022) found that for adults who had previously received a full COVID-19 vaccine regimen of either Moderna, Pfizer, or Johnson & Johnson, an additional […]
Read MoreAUTHORS: Aichholz, Pudkrong K. MD et al Anesthesia & Analgesia: May 07, 2022 BACKGROUND: Incorporation of massive transfusion protocols (MTPs) into acute major trauma care has reduced hemorrhagic mortality, but the threshold and timing of platelet transfusion in MTP are controversial. This study aimed to describe early (first 4 hours) platelet transfusion practice in a setting […]
Read MoreDG Journal Club AUTHORS: Seoyeong Park, Karam Nam, Tae Kyong Kim Anesth Analg. 2022 May 1; 134(5): 1021-1027 BACKGROUND The fibrinogen-to-albumin ratio (FAR) is a recently introduced prognostic marker for patients with coronary artery disease. The present study investigated whether the FAR is associated with clinical outcome after off-pump coronary artery bypass grafting (OPCAB). METHODS […]
Read MoreThis is for when we give a post COVID pt an anesthetic NEJM Journal Watch Bruce Soloway, MD, reviewing Katsoularis I et al. BMJ 2022 Apr 6 But risks are less elevated for those who do not require hospitalization. People with severe COVID-19 are at excess risk for venous thromboembolism (VTE), but whether risk also rises among patients […]
Read MoreAUTHORS: Mazzeffi, Michael A. MD, MPH, MSc et al Anesthesia & Analgesia: April 2022 BACKGROUND: Peripheral nerve blocks (PNBs) are used to provide postoperative analgesia after total mastectomy. PNBs improve patient satisfaction and decrease postoperative opioid use, nausea, and vomiting. Few studies have examined whether there is racial-ethnic disparity in the use of PNBs for patients […]
Read MoreDG Journal Club Shirley Jiang, Monica Tang Clin Rev Allergy Immunol. 2022 Apr 28 [Epub ahead of print] Local anesthetics (LA) are commonly used in procedures and in topical agents for pain management. With the increasing use of LA drugs, the management of LA reactions is more frequently encountered in the office and in operating […]
Read MoreDG Journal Club AUTHORS: Jun Okuda, Takeshi Suzuki, Kenta Wakaizumi, Jungo Kato J Cardiothorac Vasc Anesth. 2022 05; 36(5): 1380-1386 OBJECTIVE Inflammatory responses play major roles in the development of acute lung injury following lung cancer surgery. The authors tested the hypothesis that thoracic epidural anesthesia (TEA) during surgery could attenuate both systemic and local […]
Read MoreDG Journal Club AUTHORS: R Trivedi, J John, A Ghodke, J Trivedi J Orthop Surg Res. 2022 Apr 18; 17(1): 241 BACKGROUND The purpose of this study was to evaluate the efficacy of intrathecal morphine (ITM) in combination with bupivacaine as pre-emptive analgesia in patients undergoing posterior lumbar fusion surgery. This is in comparison with […]
Read MoreDG Journal Club Yoshinari Morimoto, Megumi Hayashi, Yuki Yao, Hitomi Nishizaki Sci Rep. 2022 Apr 15; 12(1): 6293 Differences between the effects of intravenous sedation with midazolam (MID) and dexmedetomidine (DEX) on the cerebral function of elderly patients with severe dementia are unclear. This study aimed to compare the effects of intravenous sedation with MID […]
Read MoreAuthors: Luuk R. van den Bersselaar, M.D.,M.Sc. et al Anesthesiology June 2022, Vol. 136, 940–953. Background The introduction of next-generation sequencing into the diagnosis of neuromuscular disorders has resulted in an increased number of newly identified RYR1 variants. The hypothesis was that there is an increased referral of patients to malignant hyperthermia units without a personal/family history of […]
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