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Author: Саrdiac Anesthesiologist Vascular thrombotic events include both deep venous thrombosis and pulmonary embolism and represent potentially preventable complications after Cardiac Surgery (CS). Patients remain hypercoagulable after CS, increasing vascular thrombotic event risk. All patients benefit from mechanical thromboprophylaxis achieved with compression stockings and/or intermittent pneumatic compression during hospitalization or until they are adequately mobile […]
Read MoreAUTHORS: Baxter, Mark G. PhD et al Anesthesia & Analgesia: December 2021 BACKGROUND: Postoperative delirium and postoperative cognitive dysfunction are the most common complications for older surgical patients. General anesthesia may contribute to the development of these conditions, but there are little data on the association of age with cognitive recovery from anesthesia in the […]
Read MoreAUTHORS: Duque, Melissa MD et al Anesthesia & Analgesia: December 2021 – Volume 133 – Issue 6 – p 1379-1386 BACKGROUND: Total knee replacement (TKR) and total hip replacement (THR) are 2 of the most common orthopedic surgical procedures in the United States. These procedures, with fairly low mortality rates, incur significant health care costs, with […]
Read MoreAUTHORS: Bass, Victoria MD et al Anesthesia & Analgesia: December 24, 2021 BACKGROUND: Serious mental health conditions (eg, anxiety and depression) are common in surgical patients, yet likely underassessed due to the time-consuming and cumbersome traditional screening process. A recently developed computerized adaptive mental health assessment tool (computerized adaptive test-mental health [CAT-MH]) allows rapid, precise, and […]
Read MoreAUTHORS: Patel, Abhilasha MD et al Anesthesia & Analgesia: December 2021 BACKGROUND: Dysregulation of immune responses to surgical stress in older patients and those with frailty may manifest as differences in inflammatory biomarkers. We conducted a systematic review and meta-analysis to examine differences in perioperative inflammatory biomarkers between older and younger patients, and between patients with […]
Read MoreThis could be important when we use general anesthesia on post-acute COVID-19 patients. Findings from a study published in Annals of Clinical and Translational Neurology showed decreased gray matter (GM) volume and increased mean diffusivity (MD) in olfactory-related regions explaining prolonged olfactory deficits in post-acute coronavirus disease 2019 (COVID-19) patients.deficit is a frequent clinical manifestation of COVID-19; […]
Read MoreAuthor: Cardiac Anesthesiologist Until recently, parenteral opioids were the mainstay of postoperative pain management after Cardiac Surgery (CS). Opioids are associated with multiple adverse effects, including sedation, respiratory depression, nausea, vomiting, and ileus. There is growing evidence that multimodal opioid-sparing approaches can adequately address pain through the additive or synergistic effects of different types of analgesics, permitting […]
Read MoreAuthor: Саrdiac Anesthesiologist Prolonged mechanical ventilation after Cardiac Surgery (CS) is associated with longer hospitalization, higher morbidity, mortality, and increased costs. Prolonged intubation is associated with both ventilator-associated pneumonia and significant dysphagia. Early extubation, within 6 hours of ICU arrival, can be achieved with time-directed extubation protocols and low-dose opioid anesthesia. This is safe (even in patients at high risk) and associated with […]
Read MoreAUTHORS: Aykanat, Verna M. FANZCA, MBBS, BMedSci (Hons) et al Anesthesia & Analgesia: December 2021 BACKGROUND: Prevention of hypotension during the intra- and postoperative period is an important goal. Peripheral administration of low-concentration norepinephrine may be a safe and effective strategy to reduce the risk of hypotension. METHODS: We conducted a 2-center, randomized pilot feasibility trial, […]
Read MoreAUTHORS: Mazzeffi, Michael MD, MPH, MSc et al Anesthesia & Analgesia: December 13, 2021 BACKGROUND: Coagulopathic bleeding is common during adult extracorporeal membrane oxygenation (ECMO), and acquired von Willebrand syndrome is a contributing factor. We compared ECMO patient blood samples that were treated in vitro with recombinant von Willebrand Factor concentrate and plasma-derived von Willebrand Factor […]
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