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AUTHORS: Zhang, Yi-Nan MD et al Anesthesia & Analgesia: December 2021 BACKGROUND: Intestinal ischemia/reperfusion (I/R) challenge often results in gut barrier dysfunction and induces distant organ injury. Dexmedetomidine has been shown to protect intestinal epithelial barrier against I/R attack. The present study aims to investigate the degree to which intestinal I/R attack will contribute to gut-vascular […]
Read MoreAuthor: Yvette Brazier MedicalNewsToday Cluster headaches can be very painful. They occur several times a day, start suddenly, and last for a limited time. The exact cause of cluster headaches remains unknown, though there are several theories. Cluster headaches occur cyclically. A bout of regular attacks, known as a cluster period, can last a few […]
Read MoreAUTHORS: Emily K Chapman, Lea Scherschinski et al. World Neurosurg. 2021 Nov BACKGROUND Increasing numbers of posterior cervical decompression and fusion (PCDF) over the past decade have raised the prospect of bundled payment plans. The American Society of Anesthesiologists (ASA) Physical Status Classification system may enable accurate estimation of healthcare costs, length of stay, and […]
Read MoreAuthor: Tony Mira F1rstNews A few months ago, we published an alert describing new hurdles Medicare put in place for anesthesia providers in connection with facet intervention cases. Now, Medicare is making it more difficult to get paid in epidural steroid injection (ESI) cases. Beginning this month, a new policy will go into effect across […]
Read MoreDG Journal Club AUTHORS: Aaron St-Laurent, Zofia Zysman-Colman et al. Paediatr Anaesth. 2021 Dec 5 Children with neruromuscular, chronic neurologic and chest wall diseases are at increased risk of post-operative respiratory complications including atelectasis, pneumonia, respiratory failure with the possible need for reintubation or even tracheostomy. These complications negatively impact patient outcomes, including increased healthcare […]
Read MoreAuthor: Kathleen davis FNP MedicalNewsToday Ketamine is a medication that doctors use as an anesthetic to induce loss of consciousness. Effects include sedation and reduced sensation of pain. The drug is a Schedule III non-narcotic that the Food and Drug Administration (FDA) has approved for use only as a general anesthetic. However, doctors sometimes prescribe it for “off-label” […]
Read MoreAUTHORS: Pensier, Joris MD et al Anesthesia & Analgesia: November 2021 Export BACKGROUND: In critically ill patients, warnings about a risk of death and acute kidney injury (AKI) with hydroxyethyl starch (HES) solutions have been raised. However, HES solutions may yet have a role to play in major abdominal surgery. This meta-analysis and trial sequential analysis […]
Read MoreAUTHORS: Kouz, Karim MD et al Anesthesia & Analgesia: December 2021 BACKGROUND: Cardiac output is an important hemodynamic variable and determines oxygen delivery. In contrast to blood pressure, cardiac output is rarely measured even in high-risk surgical patients, suggesting that clinicians consider blood pressure to be a reasonable indicator of systemic blood flow. However, the relationship […]
Read MoreAuthors: Nadav Y. Schacham, M.D. et al Anesthesiology November 2021. Background Age- and sex-specific reference nomograms for intraoperative blood pressure have been published, but they do not identify harm thresholds. The authors therefore assessed the relationship between various absolute and relative characterizations of hypotension and acute kidney injury in children having noncardiac surgery. Methods The […]
Read MoreAuthors: Ricardo Alvarez-Jimenez, M.D., Ph.D. et al Anesthesiology December 2021. Background Numerous pharmacokinetic models have been published aiming at more accurate and safer dosing of dexmedetomidine. The vast majority of the developed models underpredict the measured plasma concentrations with respect to the target concentration, especially at plasma concentrations higher than those used in the original […]
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