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AUTHORS: Hofer, Ira S. MD et al Anesthesia & Analgesia: September 2021 – Volume 133 – Issue 3 – p 698-706 BACKGROUND: The introduction of electronic health records (EHRs) has helped physicians access relevant medical information on their patients. However, the design of EHRs can make it hard for clinicians to easily find, review, and document […]
Read MoreAUTHORS: Xuan, Chengluan MD, PhD et al Anesthesia & Analgesia: September 2021 – Volume 133 – Issue 3 – p 620-629 BACKGROUND: Peripheral nerve block (PNB) with perineural local anesthetic is used for anesthesia or analgesia with many benefits. To extend these benefits, various adjuvant drugs have been used to prolong the duration of analgesia. We […]
Read MoreAUTHORS: O’Bryan, Liam J. MD et al Anesthesia & Analgesia: August 10, 2021 BACKGROUND: The perioperative inflammatory response may be implicated in adverse outcomes including neurocognitive dysfunction and cancer recurrence after oncological surgery. The immunomodulatory role of anesthetic agents has been demonstrated in vitro; however, its clinical relevance is unclear. The purpose of this meta-analysis was […]
Read MoreAUTHORS: Lu, Shu Yang MD et al Anesthesia & Analgesia: August 10, 2021 BACKGROUND: The association between obesity, or elevated body mass index (BMI), and outcomes in patients receiving venoarterial extracorporeal membrane oxygenation (VA-ECMO) has not been well established. Recent studies in patients receiving venovenous ECMO did not detect an association between obesity and increased mortality. […]
Read MoreAuthor: Ashok C. Kewalramani, DO, DABA, DABFM ASA Monitor September 2021, Vol. 85, 33. “The best way to predict the future is to create it….” –Abraham Lincoln The Oxford Dictionary defines “locum” as a person who stands in temporarily for another member of the same profession, especially for a physician, chemist, or member of the clergy. By […]
Read MoreAuthor” Tony Mira F1rstNews Summary: Not every anesthesia case ends as planned. Some never get off the ground. In such circumstances, are there still opportunities for reimbursement? Today’s article explores those possibilities. All good things must come to an end, or so the saying goes. The problem arises when they come to an end too soon—suddenly […]
Read MoreAUTHORS: Ing, Caleb MD, MS et al Anesthesia & Analgesia: September 2021 – Volume 133 – Issue 3 – p 595-605 BACKGROUND: Exposure to surgery and anesthesia in early childhood has been found to be associated with an increased risk of behavioral deficits. While the US Food and Drug Administration (FDA) has warned against prenatal exposure […]
Read MoreAUTHORS: Ye, Yingchao MD et al Anesthesia & Analgesia: October 2021 – Volume 133 – Issue 4 – p 1048-1059 BACKGROUND: Cardiotoxicity can be induced by the commonly used amide local anesthetic, bupivacaine. Bupivacaine can inhibit protein kinase B (AKT) phosphorylation and activated adenosine monophosphate–activated protein kinase alpha (AMPKα). It can decouple mitochondrial oxidative phosphorylation […]
Read MoreDG Journal Club AUTHORS: Ping-Ping Jiang, Yan-Xia Guo et al. J Clin Pharm Ther. 2021 Sep 12 WHAT IS KNOWN AND OBJECTIVE Remifentanil can effectively decrease the sevoflurane concentration to block sympathetic adrenergic response to CO 2 pneumoperitoneum stimulus,and liver dysfunction will significantly reduce the MAC BAR (minimum alveolar concentration for blocking adrenergic response) of […]
Read MoreDG Journal Club AUTHORS: Alicia Lew, John M Morrison et al. Paediatr Anaesth. 2021 Sep 12 BACKGROUND Volatile anesthetic agents are described as rescue therapy for children invasively ventilated for critical asthma. Yet, data are currently limited to case series. AIMS Using the Virtual Pediatric Systems database, we assessed children admitted to a pediatric intensive […]
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