Month: August 2021

Uncategorized Published - 31 August, 2021    By - Dr Clemens
Study suggests awake prone positioning may reduce incidence of treatment failure in patients with hypoxaemic respiratory failure due to COVID-19

DG Alerts Awake prone positioning of patients with hypoxaemic respiratory failure due to coronavirus disease 2019 (COVID-19) supported with high-flow nasal cannula reduced the incidence of treatment failure and the need for intubation without any signal of harm, according to a study published in The Lancet Respiratory Medicine. “Awake prone positioning has been reported to improve […]

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Uncategorized Published - 31 August, 2021    By - Dr Clemens
COVID-19 and the Brain

Authors: Timothy Gaulton, MD, MSc and Daniel J. Cole, MD, FASA ASA Monitor January 2021, Vol. 85, 25. “He seems a little off.” He was one of the first patients admitted to my (TG) hospital’s ICU with hypoxemic respiratory failure from COVID-19. Yet in contrast to the majority of other patients with this disease who presented […]

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Uncategorized Published - 31 August, 2021    By - Dr Clemens
2022 Proposed Medicare Fee Schedule: Additional Provisions for Anesthesia and Pain

Author: Tony Mira F1str News Last month, we published an alert outlining the provisions of the 2022 Medicare Physician Fee Schedule (PFS) Proposed Rule (PR) that were most pertinent to the practice of anesthesia. As promised in that alert, this article will act to provide further details arising from the PR that may impact our […]

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Uncategorized Published - 31 August, 2021    By - Dr Clemens
Lower urinary tract symptoms are associated with musculoskeletal pain among older men: Preliminary evidence for central sensitization as a mechanism?

This is for our readers that treat pain patients DG Journal Club AUTHORS: Angela Senders, Scott R Bauer et al. Neurourol Urodyn. 2021 Aug AIMS Features of central sensitization (CS) are present in almost all chronic pain conditions, including painful urinary conditions and back pain. Recently CS was proposed as a mechanism of nonpainful lower […]

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Uncategorized Published - 31 August, 2021    By - Dr Clemens
Inflammatory Biomarker Levels After Propofol or Sevoflurane Anesthesia

AUTHORS: O’Bryan, Liam J. MD et al Anesthesia & Analgesia: August 2021 BACKGROUND: The perioperative inflammatory response may be implicated in adverse outcomes including neurocognitive dysfunction and cancer recurrence after oncological surgery. The immunomodulatory role of anesthetic agents has been demonstrated in vitro; however, its clinical relevance is unclear. The purpose of this meta-analysis was to […]

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Uncategorized Published - 30 August, 2021    By - Dr Clemens
Benefits and Risks of Dexamethasone in Noncardiac Surgery

Authors: Paul S. Myles, M.B.B.S., M.P.H., M.D., D.Sc., F.C.A.I., F.A.N.Z.C.A., F.R.C.A., F.A.H.M.S et al  Anesthesiology August 2021. Dexamethasone is a commonly used drug in anesthesia and surgery. The purported beneficial effects are diverse, especially for the prophylaxis and treatment of postoperative nausea and vomiting, but the optimal dose and the clinical implications of potential side […]

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Uncategorized Published - 30 August, 2021    By - Dr Clemens
FDA warns that iPhone can interfere with implanted cardiac devices

Author: Jessica Kim Cohen Modern Healthcare Magnets in Apple’s latest smartphone, the iPhone 12, can trigger a setting in some implantable cardiac devices that temporarily disable the devices, according to Food and Drug Administration researchers. The study, published in the journal Heart Rhythm this week, reinforces existing recommendations from the FDA urging patients to keep some consumer electronic devices […]

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Uncategorized Published - 30 August, 2021    By - Dr Clemens
Does chronic pain raise the risk of dementia, Alzheimer’s, or stroke?

Author: Beth JoJack Medical News Today Patients who reported experiencing widespread pain had an increased incidence of all-cause dementia, Alzheimer’s disease, and stroke. This increased risk is independent of factors such as age, health, or sociodemographic circumstance. Researchers analyzed data from 2,464 participants of the Framingham Offspring Study Cohort, who underwent examination by health practitioners […]

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Uncategorized Published - 30 August, 2021    By - Dr Clemens
Error Traps in Pediatric Regional Anesthesia

DG Journal Club AUTHORS: Melissa M Masaracchia, Rani A Sunder et al. Paediatr Anaesth. 2021 Aug Ultrasound-guided nerve blocks have revolutionized the way we provide regional anesthesia. By providing effective perioperative pain control, regional anesthesia reduces opioid consumption, decreases length of stay, and increases patient/parental satisfaction. However, error traps (circumstances that lead to erroneous actions) […]

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Uncategorized Published - 30 August, 2021    By - Dr Clemens
Apelin-13 Reverses Bupivacaine-Induced Cardiotoxicity via the Adenosine Monophosphate–Activated Protein Kinase Pathway

AUTHORS: Ye, Yingchao MD et al Anesthesia & Analgesia: August 9, 2021 BACKGROUND:  Cardiotoxicity can be induced by the commonly used amide local anesthetic, bupivacaine. Bupivacaine can inhibit protein kinase B (AKT) phosphorylation and activated adenosine monophosphate–activated protein kinase alpha (AMPKα). It can decouple mitochondrial oxidative phosphorylation and enhance reactive oxygen species (ROS) production. Apelin enhances […]

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