Month: July 2021

Uncategorized Published - 1 July, 2021    By - Dr Clemens
Comparative evaluation of intravenous dexketoprofen and paracetamol in the management of pain induced by sore throat

DG Journal Club AUTHORS: Uzeyir Cimen, Atakan Yilmaz et al. Int J Clin Pract. 2021 Jun 12 OBJECTIVES Sore throat is one of the most prevalent causes of emergency visits. The chief purpose of this clinical report is to investigate the effectiveness of intravenous (IV) dexketoprofen and paracetamol drugs relative to each other in relieving […]

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Uncategorized Published - 1 July, 2021    By - Dr Clemens
Effects of behavioural exercise therapy on the effectiveness of multidisciplinary rehabilitation for chronic non-specific low back pain

DG Journal Club AUTHORS: Jana Semrau, Christian Hentschke et al. BMC Musculoskelet Disord. 2021 May 29; 22(1): 500 BACKGROUND The long-term effects of behavioural medical rehabilitation (BMR), as a type of multidisciplinary rehabilitation, in the treatment of chronic non-specific low back pain (CLBP) have been shown. However, the specific effects of behavioural exercise therapy (BET) […]

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Uncategorized Published - 1 July, 2021    By - Dr Clemens
Possible immunoglobulin-E-dependent sugammadex-induced anaphylaxis caused by an epitope other than γ-cyclodextrin

DG Journal Club AUTHORS: Tatsuo Horiuchi, Tomonori Takazawa et al. J Med Case Rep. 2021 Jun 5; 15(1): 313 BACKGROUND Sugammadex is a synthetic γ-cyclodextrin derivative designed to selectively bind to steroidal neuromuscular blocking agents and reverse their effects. Although many cases of sugammadex-induced anaphylaxis have been reported, few studies have investigated the underlying mechanism. […]

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Uncategorized Published - 1 July, 2021    By - Dr Clemens
Effects of the ABCB1 c.3435C>T (rs1045642) Polymorphism on Heat Pain Perception in Opioid-Free Adults With Chronic Pain

AUTHORS: Hooten, W. Michael MD et al Anesthesia & Analgesia: June 2021 BACKGROUND: The adenosine triphosphate-binding cassette, subfamily B, member 1 gene (ABCB1) encodes P-glycoprotein (P-gp) that influences the intracellular transport of solutes including endogenous opioid peptides. The primary objective of this study was to determine the effects of the ABCB1 polymorphism c.3435C>T (rs10454642) on heat pain (HP) […]

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