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AUTHORS: Stundner, Ottokar MD, MBA et al Anesthesia & Analgesia: June 2021 BACKGROUND: An increasing body of evidence demonstrates an association between obstructive sleep apnea (OSA) and adverse perioperative outcomes. However, large-scale data on open colectomies are lacking. Moreover, the interaction of obesity with OSA is unknown. This study examines the impact of OSA, obesity, or […]
Read MoreAUTHORS: Lee, Allison MD, MS et al Anesthesia & Analgesia: June 2021 BACKGROUND: Cervical cerclage is a short ambulatory procedure. For spinal anesthesia, local anesthetic agents with rapid postoperative resolution are desired. We hypothesized that in combination with fentanyl, intrathecal 2-chloroprocaine would produce earlier resolution of motor block, resulting in shorter time to meet recovery room […]
Read MoreAUTHORS: Su, Lin MD, PhD et al Anesthesia & Analgesia: June 2021 BACKGROUND: Remifentanil can induce postinfusion cold hyperalgesia. N-methyl-d-aspartate receptor (NMDAR) activation and upregulation of transient receptor potential melastatin 8 (TRPM8) membrane trafficking in dorsal root ganglion (DRG) are critical to cold hyperalgesia derived from neuropathic pain, and TRPM8 activation causes NMDAR-dependent cold response. Contribution of […]
Read MoreAuthors: Thiele, Robert H. MD et al Anesthesia & Analgesia: June 2021 Abstract While intraoperative mortality has diminished greatly over the last several decades, the risk of death within 30 days of surgery remains stubbornly high and is ultimately related to perioperative organ failure. Perioperative strokes, while rare (<2% in noncardiac surgery), are associated with a […]
Read MoreAUTHORS: Won, Dongwook MD et al Anesthesia & Analgesia: June 2021 BACKGROUND: Cricoid pressure has been used as a component of the rapid sequence induction and intubation technique. However, concerns have been raised regarding the effectiveness and safety of cricoid pressure. Paratracheal pressure, a potential alternative to cricoid pressure to prevent regurgitation of gastric contents or […]
Read MoreAuthor: Tony Mira F1rstNews The anticipation is palpable. It’s the early 1970s and you’ve just paid a whopping $7 to hear the Who, live and in concert. The hall is full. The audience is cranked and ready to rock; but before Roger Daltrey can come on stage to sing Pinball Wizard and assure you that We […]
Read MoreDG Journal Club AUTHORS: Sujung Park, Ji-Ho Kim et al. Paediatr Anaesth. 2021 May BACKGROUND Although a neuromuscular blocking agent during induction of anesthesia is the standard of care in adults, some pediatric anaesthesiologists remain concerned about their use for several reasons. Therefore, propofol and short-acting opioids with a moderate concentration of sevoflurane have been […]
Read MoreAUTHORS: Nasr, Viviane G. MD et al Anesthesia & Analgesia: May 2021 BACKGROUND: The association between race and perioperative outcomes has been evaluated in adult cardiac surgical and in healthy pediatric patients but has not been evaluated in children with congenital heart disease (CHD) presenting for noncardiac procedures. This study compares the incidence of the primary […]
Read MoreDG Alert Percutaneous peripheral nerve stimulation yields impressive reductions in pain scores and opioid use during the first week after common orthopaedic surgery procedures, according to a study published online first in the journal Anesthesiology. The benefits of postoperative nerve stimulation were “much greater than what we had anticipated, concurrently reducing pain scores by more than […]
Read MoreAUTHORS: McGuigan, Steven MBChB et al Anesthesia & Analgesia: May 2021 BACKGROUND: Depth-of-anesthesia monitoring is often utilized for patients receiving xenon anesthesia. Processed electroencephalogram (EEG) depth-of-anesthesia monitoring relies to a significant extent on frequency domain analysis of the frontal EEG, and there is evidence that the spectral features observed under anesthesia vary significantly between anesthetic agents. […]
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