Month: May 2021

Uncategorized Published - 17 May, 2021    By - Dr Clemens
Isoflurane Suppresses Hippocampal High-frequency Ripples by Differentially Modulating Pyramidal Neurons and Interneurons in Mice

Authors: Wenling Zhao, M.D. et al Anesthesiology May 2021. Background Isoflurane can induce anterograde amnesia. Hippocampal ripples are high-frequency oscillatory events occurring in the local field potentials of cornu ammonis 1 involved in memory processes. The authors hypothesized that isoflurane suppresses hippocampal ripples at a subanesthetic concentration by modulating the excitability of cornu ammonis 1 […]

Read More
Uncategorized Published - 14 May, 2021    By - Dr Clemens
The Association of Dexmedetomidine on Perioperative Opioid Consumption in Children Undergoing Adenotonsillectomy With and Without Obstructive Sleep Apnea

AUTHORS: Adler, Adam C. MS, MD, FAAP, FASE et al Anesthesia & Analgesia: January 15, 2021 BACKGROUND: Dexmedetomidine is used to reduce opioid consumption in pediatric anesthesia. However, there is conflicting evidence in pediatric adenotonsillectomy literature regarding the total perioperative opioid-sparing effects of dexmedetomidine. The aim of this study was to examine the association between dexmedetomidine […]

Read More
Uncategorized Published - 14 May, 2021    By - Dr Clemens
A Case Report from the Anesthesia Incident Reporting System

ASA Monitor February 2021, Vol. 85, 11–12. CASE 2021-2: Systems Problem An urgent caesarean section presented to the OR when one of the narcotic dispensing drawers was unable to be closed. This disabled the entire cart, which was a combined automated medication dispensing system and equipment storage device. The manufacturing company made the recommendation to […]

Read More
Uncategorized Published - 14 May, 2021    By - Dr Clemens
Sex-Specific Associations Between Preoperative Anemia and Postoperative Clinical Outcomes in Patients Undergoing Cardiac Surgery

AUTHORS: Ripoll, Juan G. MD et al Anesthesia & Analgesia: April 2021 – Volume 132 – Issue 4 – p 1101-1111 BACKGROUND: Preoperative anemia is common in cardiac surgery, yet there were limited data describing the role of sex in the associations between anemia and clinical outcomes. Understanding these relationships may guide preoperative optimization efforts. METHODS: […]

Read More
Uncategorized Published - 14 May, 2021    By - Dr Clemens
Epidural Use at Birth Not Linked to Autism Risk

DG News Having an epidural during childbirth was not associated with a greater risk of autism in the child, according to a study published in JAMA Pediatrics. “We did not find evidence for any genuine link between having an epidural and putting your baby at increased risk of autism spectrum disorder,” said senior author Alexander Butwick, […]

Read More
Uncategorized Published - 14 May, 2021    By - Dr Clemens
A Retrospective Analysis Demonstrates That a Failure to Document Key Comorbid Diseases in the Anesthesia Preoperative Evaluation Associates With Increased Length of Stay and Mortality

AUTHORS: Hofer, Ira S. MD et al Anesthesia & Analgesia: January 15, 2021  BACKGROUND: The introduction of electronic health records (EHRs) has helped physicians access relevant medical information on their patients. However, the design of EHRs can make it hard for clinicians to easily find, review, and document all of the relevant data, leading to documentation […]

Read More
Uncategorized Published - 13 May, 2021    By - Dr Clemens
Patient Involvement in Anesthesia Decision-making: A Qualitative Study of Knee Arthroplasty

Authors:  Veena Graff, M.D. et al Anesthesiology April 2021. Background Calls to better involve patients in decisions about anesthesia—e.g., through shared decision-making—are intensifying. However, several features of anesthesia consultation make it unclear how patients should participate in decisions. Evaluating the feasibility and desirability of carrying out shared decision-making in anesthesia requires better understanding of preoperative […]

Read More
Uncategorized Published - 13 May, 2021    By - Dr Clemens
Intraoperative Hypotension and Myocardial Infarction Development Among High-Risk Patients Undergoing Noncardiac Surgery

AUTHORS: Hallqvist, Linn MD, PhD Student, DESA et al Anesthesia & Analgesia: February 5, 2021 – Volume – Issue – 10.1213/ BACKGROUND: Hemodynamic instability during anesthesia and surgery is common and associated with cardiac morbidity and mortality. Information is needed regarding optimal blood pressure (BP) threshold in the perioperative period. Therefore, the effect of intraoperative hypotension […]

Read More
Uncategorized Published - 13 May, 2021    By - Dr Clemens
Study highlights new heart failure diagnoses among patients hospitalised for COVID-19

DG Alerts Patients hospitalised with coronavirus disease 2019 (COVID-19) may be at risk of developing heart failure even if they do not have a previous history of heart disease or cardiovascular risk factors, according to a study published in the Journal of the American College of Cardiology. For the study, researchers led by Jesus Alvarez-Garcia MD, […]

Read More
Uncategorized Published - 13 May, 2021    By - Dr Clemens
Presence of heart failure with preserved ejection fraction in COVID-19 patients

DG Alerts Patients hospitalised with coronavirus disease 2019 (COVID-19) frequently showed high likelihood of presence of heart failure with preserved ejection fraction (HFpEF) that was associated with cardiac structural and functional alterations, and myocardial injury, according to a study published in the European Journal of Heart Failure. The study included 64 hospitalised COVID-19 patients (mean age […]

Read More