Month: May 2021

Uncategorized Published - 27 May, 2021    By - Dr Clemens
Safety and Efficacy of the Combination of Propofol and Ketamine for Procedural Sedation/Anesthesia in the Pediatric Population

AUTHORS: Hayes, Jason A. MD et al Anesthesia & Analgesia: April 2021 – Volume 132 – Issue 4 – p 979-992 BACKGROUND:  Drugs such as propofol and ketamine are used alone or in combination to provide sedation for medical procedures in children. The purpose of this systematic review was to compare the safety and effectiveness of […]

Read More
Uncategorized Published - 26 May, 2021    By - Dr Clemens
Effect of Dural Puncture Epidural Technique Combined With Programmed Intermittent Epidural Bolus on Labor Analgesia Onset and Maintenance

AUTHORS: Song, Yujie MD et al Anesthesia & Analgesia: April 2021 – Volume 132 – Issue 4 – p 971-978 BACKGROUND:  The dural puncture epidural (DPE) technique is associated with faster onset than the conventional epidural (EP) technique for labor analgesia. The programmed intermittent epidural bolus (PIEB) mode for maintaining labor analgesia allows for lower anesthetic […]

Read More
Uncategorized Published - 26 May, 2021    By - Dr Clemens
Association Between High Body Mass Index and Mortality Following Myocardial Injury After Noncardiac Surgery

AUTHORS: Lee, Seung-Hwa MD et al Anesthesia & Analgesia: April 2021 – Volume 132 – Issue 4 – p 960-968 BACKGROUND:  Despite an association between obesity and increased risks for various diseases, obesity has been paradoxically reported to correlate with improved mortality in patients with established cardiovascular disease. However, its effect has not been evaluated to […]

Read More
Uncategorized Published - 26 May, 2021    By - Dr Clemens
Improving Adherence to Intraoperative Lung-Protective Ventilation Strategies Using Near Real-Time Feedback and Individualized Electronic Reporting

AUTHORS: Parks, Dale A. PhD et al Anesthesia & Analgesia: May 2021 – Volume 132 – Issue 5 – p 1438-1449 BACKGROUND:  Postoperative pulmonary complications can have a significant impact on the morbidity and mortality of patients undergoing major surgeries. Intraoperative lung protective strategies using low tidal volume (TV) ventilation and positive end-expiratory pressure (PEEP) have […]

Read More
Uncategorized Published - 26 May, 2021    By - Dr Clemens
Aspirin Use Is Associated With Decreased Mechanical Ventilation, Intensive Care Unit Admission, and In-Hospital Mortality in Hospitalized Patients With Coronavirus Disease 2019

AUTHORS: Chow, Jonathan H. MD et al Anesthesia & Analgesia: April 2021 – Volume 132 – Issue 4 – p 930-941 BACKGROUND:  Coronavirus disease-2019 (COVID-19) is associated with hypercoagulability and increased thrombotic risk in critically ill patients. To our knowledge, no studies have evaluated whether aspirin use is associated with reduced risk of mechanical ventilation, intensive […]

Read More
Uncategorized Published - 26 May, 2021    By - Dr Clemens
Seven-year follow up of Persistent Postsurgical Pain in cardiac surgery patients

DG Journal Club Suzanne R Harrogate, Jackie A Cooper et al. Eur J Pain. 2021 May BACKGROUND Our aim was to describe the long-term prevalence, risk factors and impact on quality of life of Persistent Postsurgical Pain (PPP) following cardiac surgery. METHODS All patients undergoing sternotomy in a single centre over a six-month period were […]

Read More
Uncategorized Published - 25 May, 2021    By - Dr Clemens
Comparison between epidural and intravenous analgesia effects on disease-free survival after colorectal cancer surgery

DG Journal Club Wiebke Falk, Anders Magnuson et al. Br J Anaesth. 2021 May BACKGROUND Thoracic epidural analgesia (TEA) has been suggested to improve survival after curative surgery for colorectal cancer compared with systemic opioid analgesia. The evidence, exclusively based on retrospective studies, is contradictory. METHODS In this prospective, multicentre study, patients scheduled for elective […]

Read More
Uncategorized Published - 25 May, 2021    By - Dr Clemens
Informed Consent: Substance and Signature

Robert Morton, CPHRM, CPPS, Assistant Vice President, Department of Patient Safety and Risk Management The Doctors Company For decades, consent documents have helped protect physicians against the claims of dissatisfied patients. Times have changed, however, and modern medicine requires a more complex and complete acknowledgment of both the patient’s and the physician’s rights and responsibilities […]

Read More
Uncategorized Published - 25 May, 2021    By - Dr Clemens
Combined Platelet and Erythrocyte Salvage: Evaluation of a New Filtration-based Autotransfusion Device

Authors: Alexandre Mansour, M.D. et al  Anesthesiology May 2021. Background The SAME device (i-SEP, France) is an innovative filtration-based autotransfusion device able to salvage and wash both red blood cells and platelets. This study evaluated the device performances using human whole blood with the hypothesis that the device will be able to salvage platelets while […]

Read More
Uncategorized Published - 25 May, 2021    By - Dr Clemens
Single dose perioperative intrathecal ketamine as an adjuvant to intrathecal bupivacaine

DG Journal Club Samantha Sohnen, Oonagh Dowling et al. J Clin Anesth. 2021 May STUDY OBJECTIVE To identify whether adding intrathecal ketamine to intrathecal bupivacaine prolongs the time to first analgesic request in adult humans. DESIGN A meta-analysis of randomized controlled trials in humans. SETTING The majority of data was obtained in an operating room […]

Read More