AUTHORS: Clunies-Ross, Natasha MBBS, FRCA et al Anesthesia & Analgesia: February 2021 – Volume 132 – Issue 2 – p 485-492 BACKGROUND: QT interval prolongation is associated with torsade de pointes but remains a poor predictor of drug torsadogenicity. Increased transmural dispersion of myocardial repolarization (TDR), measured as the time interval between the peak and end […]
Read MoreAUTHORS: Wingert, Theodora MD et al Anesthesia & Analgesia: February 2021 – Volume 132 – Issue 2 – p 332-340 BACKGROUND: Acute kidney injury (AKI) has been well documented in adults after noncardiac surgery and demonstrated to be associated with adverse outcomes. We report the prevalence of AKI after pediatric noncardiac surgery, the perioperative factors associated […]
Read MoreDG News Reducing the standard dose of IV-administered ketamine in half is as effective as the larger, standard dose in reducing pain in adults with acute pain, according to a study published in the journal Academic Emergency Medicine. Ketamine is known to provide pain relief comparable to opioid medications, which are highly addictive. For the current […]
Read MoreDG News Author: Brian Hoyle Local anesthetics reduce opioid requirement and pain scores after lumpectomy and sentinel node biopsy with multimodal analgesia, according to a study presented at the 2021 Virtual Meeting of the Society of Surgical Oncology (SSO). “Multimodal analgesia during ambulatory breast surgery is associated with reduced postoperative opioid use and pain scores, […]
Read MoreAUTHORS: Trentino, Kevin M. MPH et al Anesthesia & Analgesia: February 2021 – Volume 132 – Issue 2 – p 344-352 BACKGROUND: In 2016, a preoperative clinic was implemented to screen, evaluate, and manage anemia and suboptimal iron stores at a major tertiary care medical center in Western Australia. Few studies compare the costs and reimbursements […]
Read MoreDG Alerts A study of more than 20,000 patients with coronavirus disease 2019 (COVID-19) who were hospitalised or died during the first wave found that the risk of worse outcomes from COVID-19 start increasing in people with a body mass index (BMI) >23 kg/m2, which is considered to be in the healthy range. The findings […]
Read MoreAUTHORS: Wu, Zhijie MD et al Anesthesia & Analgesia: February 2021 – Volume 132 – Issue 2 – p 320-328 BACKGROUND: Consecutive exposure to high-dose remifentanil during anesthesia may induce remifentanil-induced postinfusion hyperalgesia (RPH). Dexmedetomidine, a highly selective α2-adrenergic receptor agonist, may have synergistic effects with opioids and aid in perioperative pain management. In this study, […]
Read MoreAUTHORS: Moon, Tiffany S. MD et al Anesthesia & Analgesia: February 2021 – Volume 132 – Issue 2 – p 308-316 BACKGROUND: Cocaine has a short biological half-life, but inactive urine metabolites may be detectable for a week following use. It is unclear if patients who test positive for cocaine but have a normal electrocardiogram and […]
Read MoreBy Alex Morrisson DG News Spinal cord stimulation using a 10 kilohertz device suppresses pain caused by diabetic neuropathy, according to a study presented at the Virtual 2021 Annual Meeting of the American Academy of Neurology (AAN). In the multicentre randomised SENZA-PDN study, patients diagnosed with diabetic neuropathy said their pain scores decreased from an […]
Read MoreDG News Having an epidural during childbirth was not associated with a greater risk of autism in the child, according to a study published in JAMA Pediatrics. “We did not find evidence for any genuine link between having an epidural and putting your baby at increased risk of autism spectrum disorder,” said senior author Alexander Butwick, […]
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