Month: April 2021

Uncategorized Published - 14 April, 2021    By - Dr Clemens
Prenatal Exposure to General Anesthesia and Childhood Behavioral Deficit

AUTHORS: Ing, Caleb MD, MS et al Anesthesia & Analgesia: January 22, 2021 – Volume – Issue – 10 BACKGROUND: Exposure to surgery and anesthesia in early childhood has been found to be associated with an increased risk of behavioral deficits. While the US Food and Drug Administration (FDA) has warned against prenatal exposure to anesthetic […]

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Uncategorized Published - 14 April, 2021    By - Dr Clemens
A Novel Perioperative Multidose Methadone-Based Multimodal Analgesic Strategy in Children Achieved Safe and Low Analgesic Blood Methadone Levels Enabling Opioid-Sparing Sustained Analgesia With Minimal Adverse Effects

AUTHORS: Sadhasivam, Senthilkumar MD, MPH, MBA, FASA et al Anesthesia & Analgesia: January 21, 2021 – Volume – Issue – 10. BACKGROUND: Intraoperative methadone, a long-acting opioid, is increasingly used for postoperative analgesia, although the optimal methadone dosing strategy in children is still unknown. The use of a single large dose of intraoperative methadone is controversial […]

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Uncategorized Published - 14 April, 2021    By - Dr Clemens
The Bitter and the Sweet: Relationship of Lactate, Glucose, and Mortality After Severe Blunt Trauma

AUTHORS: Richards, Justin E. MD et al Anesthesia & Analgesia: December 30, 2020 – Volume – Issue – 10. BACKGROUND: Hyperglycemia is associated with mortality after trauma; however, few studies have simultaneously investigated the association of depth of shock and acute hyperglycemia. We evaluated lactate, as a surrogate measure for depth of shock, and glucose levels […]

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Uncategorized Published - 14 April, 2021    By - Dr Clemens
Residual Neuromuscular Block Prediction Score Versus Train-of-Four Ratio and Respiratory Outcomes

AUTHORS: Patrocínio, Maria D. MD et al Anesthesia & Analgesia: January 22, 2021 – Volume – Issue – 10. BACKGROUND: Residual neuromuscular blockade is associated with an increased incidence of postoperative respiratory complications. The REsidual neuromuscular block Prediction Score (REPS) identifies patients at high risk for residual neuromuscular blockade after surgery. METHODS: A total of 101,510 […]

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Uncategorized Published - 14 April, 2021    By - Dr Clemens
Multidisciplinary programme for rehabilitation of chronic low back pain – factors predicting successful return to work

DG Journal Club AUTHORS: Gabriel Ching Ngai Leung, Prudence Wing Hang Cheung et al. BMC Musculoskelet Disord. 2021 Mar 6; 22(1): 251 BACKGROUND There are no clear indicators for predicting return to work for patients with chronic low back pain (LBP). We aim to report the outcomes of a 14-week multidisciplinary programme targeting patients with […]

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Uncategorized Published - 13 April, 2021    By - Dr Clemens
Free Hemoglobin Ratio as a Novel Biomarker of Acute Kidney Injury After On-Pump Cardiac Surgery

AUTHORS: Hu, Jie MD, PhD et al Anesthesia & Analgesia: January 21, 2021 – Volume – Issue – 10 BACKGROUND: Cardiac surgery with cardiopulmonary bypass (CPB) is associated with a high risk of postoperative acute kidney injury (AKI). Due to limitations of current diagnostic strategies, we sought to determine whether free hemoglobin (fHb) ratio (ie, levels […]

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Uncategorized Published - 13 April, 2021    By - Dr Clemens
Comparison of the Analgesic Duration of 0.5% Bupivacaine With 1:200,000 Epinephrine Versus 0.5% Ropivacaine Versus 1% Ropivacaine for Low-Volume Ultrasound-Guided Interscalene Brachial Plexus Block

AUTHORS: Safa, Ben MD et al Anesthesia & Analgesia: April 2021 – Volume 132 – Issue 4 – p 1129-1137 BACKGROUND:  Bupivacaine and ropivacaine are the preferred long-acting local anesthetics for peripheral nerve blocks as they provide prolonged analgesia in the postoperative period. No studies have directly compared the analgesic duration of these commonly used local […]

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Uncategorized Published - 13 April, 2021    By - Dr Clemens
COVID-19: Anesthesia Machine Circuit Pressure During Use As An Improvised ICU Ventilator

AUTHORS: Pham, Vinh MD et al Anesthesia & Analgesia: January 12, 2021 – Volume – Issue – 10. Background: Use of anesthesia machines as improvised ICU ventilators may occur in locations where waste anesthesia gas suction(WAGS) is unavailable. Anecdotal reports suggest as much as 18 cmH2O positive end-expiratory pressure(PEEP) being inadvertently applied under these circumstances, accompanied […]

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Uncategorized Published - 13 April, 2021    By - Dr Clemens
The effects of COVID-19 on pediatric anesthesiologists

AUTHORS: Margolis, Rebecca D. DO, FAOCA et al Anesthesia & Analgesia: January 12, 2021 – Volume – Issue – 10.1 Background: The COVID-19 pandemic has affected the personal and professional lives of all healthcare workers. Anesthesiologists frequently perform virus-aerosolizing procedures, such as intubation and extubation, that place them at increased risk of infection. We sought to determine how […]

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Uncategorized Published - 13 April, 2021    By - Dr Clemens
Multimodal Nonopioid Pain Protocol Provides Equivalent Pain Versus Opioid Control Following Meniscus Surgery

DG Journal Club AUTHORS: Toufic R Jildeh, Kelechi R Okoroha et al. Arthroscopy. 2021 Mar 10 PURPOSE To assess the effectiveness of a nonopioid pain regimen in controlling postoperative pain as compared to a traditional opioid pain control following primary meniscectomy or meniscal repair. STUDY DESIGN Level of Evidence: Level I, Prospective Randomized Controlled Trial […]

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