Month: January 2021

Uncategorized Published - 27 January, 2021    By - Dr Clemens
Neuromuscular Blockade Monitoring in Acute Respiratory Distress Syndrome

AUTHORS: Rezaiguia-Delclaux, Saïda MD et al Anesthesia & Analgesia: September 2020 BACKGROUND: Whether train-of-four (TOF) monitoring is more effective than clinical monitoring to guide neuromuscular blockade (NMB) in patients with acute respiratory distress syndrome (ARDS) is unclear. We compared clinical monitoring alone or with TOF monitoring to guide atracurium dosage adjustment with respect to drug […]

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Uncategorized Published - 27 January, 2021    By - Dr Clemens
An assessment of perioperative respiratory adverse events and difficult intubation in pediatric patients with trisomy 21

DG Journal Club AUTHORS: Taylor Graber, Paola Baskin et al. Paediatr Anaesth. 2021 Jan INTRODUCTION Several prior studies have demonstrated an association between trisomy 21 and airway-related anesthetic complications. However, there is a paucity of large clinical studies characterizing the airway challenges associated with trisomy 21. In this analysis we examine anesthetic related airway complications […]

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Uncategorized Published - 27 January, 2021    By - Dr Clemens
High-frequency spinal cord stimulation in failed back surgery syndrome patients with predominant low back pain-single-center experience

DG Journal Club Authors: Stefan Motov, Kaywan Aftahy et al. Neurosurg Rev. 2021 Jan Treatment of patients with failed back surgery syndrome (FBSS) with predominant low back pain (LBP) remains challenging. High-frequency spinal cord stimulation (HF10 SCS) is believed to achieve significant pain reduction. We aimed to evaluate the real-life efficacy of HF-10 SCS in […]

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Uncategorized Published - 27 January, 2021    By - Dr Clemens
An Electroencephalogram Metric of Temporal Complexity Tracks Psychometric Impairment Caused by Low-dose Nitrous Oxide

Authors: Xavier C. E. Vrijdag, M.Sc. et al  Anesthesiology February 2021, Vol. 134, 202–218. Background Nitrous oxide produces non–γ-aminobutyric acid sedation and psychometric impairment and can be used as scientific model for understanding mechanisms of progressive cognitive disturbances. Temporal complexity of the electroencephalogram may be a sensitive indicator of these effects. This study measured psychometric performance […]

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Uncategorized Published - 27 January, 2021    By - Dr Clemens
Perioperative probiotic treatment decreased the incidence of postoperative cognitive impairment in elderly patients following non-cardiac surgery

DG Journal Club AUTHORS: Pingzhu Wang, Xinlin Yin et al. Clin Nutr. 2021 Jan; 40(1): 64-71 BACKGROUND Given that population aging is a global health challenge, the high prevalence of postoperative neurocognitive impairment in elderly patients necessitates the development of novel simple and effective prevention methods. OBJECTIVE To evaluate the effects of perioperative application of […]

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Uncategorized Published - 27 January, 2021    By - Dr Clemens
Altered mentation or stroke on admission associated with higher risk of in-hospital mortality in patients with COVID-19

DG Aleerts The incidence of altered mentation or stroke on admission predicts a modest but significantly higher risk of in-hospital mortality independent of disease severity among patients with coronavirus disease 2019 (COVID-19), according to a study published in Neurology. “We present the largest inpatient cohort of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infected patients to […]

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Uncategorized Published - 26 January, 2021    By - Dr Clemens
Hyperbaric prilocaine vs. hyperbaric bupivacaine for spinal anaesthesia in women undergoing elective caesarean section

DG Journal Club AUTHORS: K Chapron, J-C Sleth et al. Anaesthesia. 2021 Jan Hyperbaric bupivacaine spinal anaesthesia remains the gold standard for elective caesarean section, but the resultant clinical effects can be unpredictable. Hyperbaric prilocaine induces shorter motor block but has not previously been studied in the obstetric spinal anaesthesia setting. We aimed to compare […]

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Uncategorized Published - 26 January, 2021    By - Dr Clemens
Comparison of Deep Sedation and General Anesthesia With an Endotracheal Tube for Transcaval Transcatheter Aortic Valve Replacement

DG Journal Club AUTHORS: Joseph A Sanders, Ashwin Vaidyanathan et al. J Cardiothorac Vasc Anesth. 2021 Jan OBJECTIVES Transcaval transcatheter aortic valve replacement (TC-TAVR) is an alternative approach to transcatheter aortic valve replacement involving deployment of the bioprosthetic valve via a conduit created from the inferior vena cava to the descending aorta in patients for […]

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Uncategorized Published - 26 January, 2021    By - Dr Clemens
Statin therapy with evolocumab reduces patient’s risk of PCI, CABG

Author: Michael Walter Cardiovascular Business News Statin therapy that includes evolocumab can help patients with stable atherosclerosis decrease their risk of undergoing percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG), according to a new study published in the Journal of the American College of Cardiology. The authors tracked data from more than 1,700 patients […]

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Uncategorized Published - 26 January, 2021    By - Dr Clemens
High-titre plasma reduces mortality risk in non-ventilated hospitalised COVID-19 patients

DG Alerts Among patients hospitalised with coronavirus disease 2019 (COVID-19) who were not receiving mechanical ventilation, transfusion of plasma with higher anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) immunoglobulin (Ig)G antibody levels was associated with a lower risk of death than transfusion of plasma with lower antibody levels, finds a study published in The New England […]

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