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AUTHORS: Candiotti, Keith A. MD et al Anesthesia & Analgesia: June 2019 – Volume 128 – Issue 6 – p 1098-1105 BACKGROUND: Postoperative nausea and vomiting (PONV) occurs commonly in surgical patients despite widespread prophylactic antiemetic use. Rescue options are currently limited. 5HT3 antagonists are most frequently used for prophylaxis, but if they fail, additional doses are […]
Read MoreAUTHORS: Holmgaard, Frederik BMSc et al Anesthesia & Analgesia: June 2019 – Volume 128 – Issue 6 – p 1081-1088 BACKGROUND: Near-infrared spectroscopy (NIRS) is used worldwide to monitor regional cerebral oxygenation (rScO2) during cardiopulmonary bypass (CPB). Intervention protocols meant to mitigate cerebral desaturation advocate to increase mean arterial pressure (MAP) when cerebral desaturation occurs. However, […]
Read MoreAuthors: Molero Y et al. BMJ 2019 Jun 12 Multiple adverse behavioral and psychomotor associations are found with these drugs although the effects might be confined to pregabalin. Clinicians often prescribe gabapentin and pregabalin for pain, sleep, and anxiety symptoms, and some view these drugs as safe alternatives to benzodiazepines and opioids in, for example, patients […]
Read MoreAUTHORS: Benzon, Honorio T. MD et al Anesthesia & Analgesia: June 2019 – Volume 128 – Issue 6 – p 1089-1096 BACKGROUND: Patients presenting for surgery may have isolated or combined prolonged activated partial thromboplastin time (aPTT) and/or prothrombin time (PT). In patients not receiving anticoagulants or with no identifiable cause for abnormal clot formation, a […]
Read MoreI thought this was interesting so I wanted to share it with our readers. By Mark Terry BioSpace In 1992, the U.S. Food and Drug Administration (FDA) developed its Accelerated Approval Program. It was designed to move certain new drugs to the market faster. The Accelerated Approval leans on a surrogate endpoint, which is a marker, such as […]
Read MoreAuthor: Tauren Dyson People with osteoarthritis who take NSAIDs have a 23 percent higher likelihood of developing cardiac disease compared to people without the condition. File Photo by Kzenon/Shutterstock Nonsteroidal anti-inflammatory drugs that treat inflammation and pain raise the risk of congenital heart disease, heart attack and other conditions for people with osteoarthritis, new findings […]
Read MoreAuthor: Ethan Covey Anesthesiology News Preoperative anxiety, measured using the modified Yale Preoperative Anxiety Scale (mYPAS), can predict rates of emergence delirium, according to a new study. “This study is important because early identification of these at-risk patients can alert the anesthesiologist to appropriately and preemptively medicate patients,” said Ali Atoot, a fourth-year medical student […]
Read MoreAUTHORS: Grabitz, Stephanie D. MD et al Anesthesia & Analgesia: June 2019 – Volume 128 – Issue 6 – p 1129-1136 BACKGROUND: Postoperative residual neuromuscular blockade continues to be a frequent occurrence with a reported incidence rate of up to 64%. However, the effect of postoperative residual neuromuscular blockade on health care utilization remains unclear. We […]
Read MoreAUTHORS: Orhurhu, Vwaire MD, MPH et al Anesthesia & Analgesia: July 2019 – Volume 129 – Issue 1 – p 241-254 BACKGROUND: IV ketamine is widely used to treat patients with chronic pain, yet the long-term impact remains uncertain. We synthesized evidence from randomized control trials to investigate the effectiveness of IV ketamine infusions for pain […]
Read MoreAuthor: Michael Vlessides Anesthesiology News Global scores from a 360-degree evaluation tool revealed higher overall scores for female fellows than male fellows, and both male and female evaluators also scored the women more positively in several competency domains. “In the past, gender bias has been a potential issue that has affected how medical students, residents […]
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