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AUTHORS: Wong, David T., MD et al Anesthesia & Analgesia: January 2019 BACKGROUND: Morbidly obese patients undergoing general anesthesia are at risk of hypoxemia during anesthesia induction. High-flow nasal oxygenation use during anesthesia induction prolongs safe apnea time in nonobese surgical patients. The primary objective of our study was to compare safe apnea time, between patients given […]
Read MoreAUTHORS: Messina, Antonio, PhD et al Anesthesia & Analgesia: December 2018 – Volume 127 – Issue 6 – p 1353–1364 BACKGROUND: Assessing the volemic status of patients undergoing surgery is part of the routine management for the anesthesiologist. This assessment is commonly performed by means of dynamic indexes based on the cardiopulmonary interaction during mechanical ventilation […]
Read MoreAUTHORS: Tassonyi, Edömér, MD, PhD, DSc et al Anesthesia & Analgesia: December 2018 – Volume 127 – Issue 6 – p 1344–1350 BACKGROUND: Certain surgical interventions may require a deep neuromuscular block (NMB). Reversal of such a block before tracheal extubation is challenging. Because anticholinesterases are ineffective in deep block, sugammadex 4 mg/kg has been recommended […]
Read MoreAUTHORS: Schacham, Yehoshua N., MD et al Anesthesia & Analgesia: December 2018 – Volume 127 – Issue 6 – p 1335–1341 BACKGROUND: We tested the primary hypothesis that final intraoperative esophageal temperature is associated with increased odds of a composite of in-hospital all-cause mortality and myocardial injury within 7 days after noncardiac surgery. Secondary exposures were […]
Read MoreAUTHORS: Nomura, Yohei, MD et al Anesthesia & Analgesia: December 2018 – Volume 127 – Issue 6 – p 1314–1322 BACKGROUND: Impaired cerebral blood flow (CBF) autoregulation during cardiopulmonary bypass (CPB) is associated with stroke and other adverse outcomes. Large and small arterial stenosis is prevalent in patients undergoing cardiac surgery. We hypothesize that large and/or […]
Read MoreAUTHORS: Sharawi, Nadir, MBBS, FRCA, MSc et al Anesthesia & Analgesia: December 2018 – Volume 127 – Issue 6 – p 1385–1395 The prevalence of neuraxial opioid–induced clinically significant respiratory depression (CSRD) after cesarean delivery is unknown. We sought to review reported cases of author-reported respiratory depression (ARD) to calculate CSRD prevalence. A 6-database literature search […]
Read MoreDr. Reddy’s Laboratories Ltd. (BSE: 500124, NSE: DRREDDY, NYSE: RDY, along with its subsidiaries together referred to as “Dr. Reddy’s”) today announced the launch of Propofol Injectable Emulsion, USP, a therapeutic equivalent generic version of DIPRIVAN (propofol) Injectable Emulsion, USP, approved by the U.S. Food and Drug Administration (USFDA). Dr. Reddy’s is committed to providing […]
Read MoreAUTHORS: Smith, Bradford B., MD et al Anesthesia & Analgesia: April 2019 – Volume 128 – Issue 4 – p 621–628 BACKGROUND: Noncardiac surgery (NCS) following percutaneous coronary intervention (PCI) with stenting is sometimes associated with major adverse cardiac events (MACEs). Second-generation drug-eluting stents (DES) were developed to decrease the incidence of MACE seen with bare […]
Read MoreAUTHORS: Cho, Brian C., MD et al Anesthesia & Analgesia: May 2019 – Volume 128 – Issue 5 – p 981–992 BACKGROUND: Erythropoietic-stimulating agents such as erythropoietin have been used as part of patient blood management programs to reduce or even avoid the use of allogeneic blood transfusions. We review the literature to evaluate the effect […]
Read MoreAUTHORS: Jabaley, Craig S., MD et al Anesthesia & Analgesia: December 24, 2018 BACKGROUND: Atypical antipsychotics are efficacious for chemoprophylaxis against chemotherapy-induced nausea and vomiting, but perioperative investigations have been scant. We sought to examine the association between chronic atypical antipsychotic therapy and the likelihood of postoperative nausea and vomiting. METHODS: In this single-center, propensity-matched, retrospective, observational study, […]
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