Month: April 2019

Uncategorized Published - 23 April, 2019    By - Dr Clemens
Perioperative Fluid Therapy for Major Surgery

Authors: Timothy E. Miller, M.B.,Ch.B., F.R.C.A. et al Anesthesiology 5 2019, Vol.130, 825-832. The goal of IV fluid administration is to restore and maintain tissue fluid and electrolyte homeostasis and central euvolemia, while avoiding salt and water excess. This will in turn facilitate tissue oxygen delivery without causing harm. Achieving optimal IV fluid therapy should […]

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Uncategorized Published - 23 April, 2019    By - Dr Clemens
Lung Recruitment in Obese Patients with Acute Respiratory Distress Syndrome

Authors: Jacopo Fumagalli, M.D. et al Anesthesiology 5 2019, Vol.130, 791-803. What We Already Know about This Topic: Obesity increases the propensity to atelectasis in acute respiratory distress syndrome, but the optimal approach to reversing this atelectasis is uncertain What This Article Tells Us That Is New: A clinical crossover study comparing three approaches to titrate […]

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Uncategorized Published - 23 April, 2019    By - Dr Clemens
Can the Brain Predict Fluid Responsiveness?

Authors: Elliot Long, B.M.B.S., F.R.A.C.P. et al Anesthesiology 5 2019, Vol.130, 674-676. “Transfontanelle measurement of respiratory variation in internal carotid artery blood flow peak velocity is a novel method for predicting fluid responsiveness [in infants].” Image: TranscranialUS. Resuscitation with IV fluid is a ubiquitous first-line form of acute circulatory support in emergency medicine, critical care, […]

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Uncategorized Published - 23 April, 2019    By - Dr Clemens
Aquaporin 5 –1364A/C Promoter Polymorphism Is Associated with Pulmonary Inflammation and Survival in Acute Respiratory Distress Syndrome

Authors: Tim Rahmel, M.D. et al Anesthesiology 3 2019, Vol.130, 404-413. What We Already Know about This Topic: Acute respiratory distress syndrome is defined according to clinical criteria, but lack of precise characterization may contribute to negative trials and impede personalized care. Polymorphisms of aquaporin-5, a key mediator of inflammation, may impact outcome. What This Article […]

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Uncategorized Published - 23 April, 2019    By - Dr Clemens
Nociception-guided versus Standard Care during Remifentanil–Propofol Anesthesia: A Randomized Controlled Trial

Authors: Fleur S. Meijer, M.D. et al Anesthesiology 5 2019, Vol.130, 745-755. What We Already Know about This Topic: The nociception level index (Medasense Biometrics Ltd., Ramat Gan, Israel), is a reliable measure of moderate to intense noxious stimulation during anesthesia and surgery What This Article Tells Us That Is New: In a randomized trial in […]

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Uncategorized Published - 23 April, 2019    By - Dr Clemens
US Cancer Patients Are Undergoing CRISPR Tests For The First Time

By David Grossman Popular Mechanics The high-profile experimental technique got a bad rap in 2018. Scientists are trying for a second introduction in 2019. For the first time, doctors in the United States have used cutting-edge CRISPR technology to treat cancer patients. Two cancer patients participating in a study with the University of Pennsylvania in […]

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Uncategorized Published - 22 April, 2019    By - Dr Clemens
Driving Pressure during Thoracic Surgery: A Randomized Clinical Trial

Authors: MiHye Park, M.D. et al Anesthesiology 3 2019, Vol.130, 385-393. What We Already Know about This Topic: Driving pressure (plateau minus end-expiratory airway pressure) is a target in patients with acute respiratory distress syndrome, and is proposed as a target during general anesthesia for patients with normal lungs. It has not been reported for […]

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Uncategorized Published - 22 April, 2019    By - Dr Clemens
Narcolepsy, Anesthesia, and Sedation

AUTHORS: Hershner, Shelley, MD et al Anesthesia & Analgesia: December 2018 A Survey of the Perioperative Experience of Patients With Narcolepsy BACKGROUND: Patients with narcolepsy may be at increased perioperative risk due to the interactions among anesthesia, narcolepsy, and narcolepsy medications. This study sought to determine the perioperative experience of narcoleptic patients undergoing anesthesia or sedation, the […]

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Uncategorized Published - 22 April, 2019    By - Dr Clemens
A Case Report From the Anesthesia Incident Reporting System

ASA Monitor 2 2019, Vol.83, 52. Review of unusual patient care experiences is a cornerstone of medical education. Each month, the AQI-AIRS Steering Committee abstracts a patient history submitted to the Anesthesia Incident Reporting System (AIRS) and authors a discussion of the safety and human factors challenges involved. Real-life case histories often include multiple clinical decisions, […]

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Uncategorized Published - 22 April, 2019    By - Dr Clemens
ACE Question

ASA Monitor 2 2019, Vol.83, 44-45. What is the most significant type of heat loss encountered by the exposed surgical patient prior to surgery? (A) Conductive (B) Radiative (C) Convective (D) Evaporative Mechanisms of heat transfer (Figure 1) should be considered when trying to prevent or reverse heat loss. Figure 1:Mechanisms of heat transfer. © 2017 […]

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