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Authors: Zhi-Fu Wu, M.D. et al Anesthesiology 11 2018, Vol.129, 932-941. What We Already Know about This Topic: Propofol may better preserve host defenses against cancer Whether cancer recurrence is less likely with propofol than volatile anesthesia remains unknown What This Article Tells Us That Is New: The authors conducted a propensity-matched retrospective analysis of 1,158 […]
Read MoreAuthors: Chung-Sik Oh, M.D., Ph.D. et al Anesthesiology 11 2018, Vol.129, 921-931. What We Already Know about This Topic: Cluster of differentiation enzymes on regulatory T cells are immunosuppressive and promote cancer recurrence The investigators tested the hypothesis that cluster of differentiation 39 and 73 expression is increased less with propofol than sevoflurane What This Article […]
Read MoreAuthors: Robert Fong, M.D., Ph.D. et al Anesthesiology 11 2018, Vol.129, 912-920. What We Already Know about This Topic: Caffeine may speed anesthetic emergence What This Article Tells Us That Is New: The authors tested the hypothesis that caffeine speeds anesthetic emergence Volunteers anesthetized with isoflurane were given caffeine (equivalent to 7.5 mg base) or placebo in […]
Read MoreAuthors: Takahiro Muramatsu, M.D. et al Anesthesiology 11 2018, Vol.129, 901-911. What We Already Know about This Topic: Sugammadex may be the best available drug to reverse residual neuromuscular blockade produced by rocuronium and vecuronium A 5% incidence of residual neuromuscular blockade has been reported after administering sugammadex without neuromuscular monitoring Elderly patients have been reported […]
Read MoreIntubation is a standard part of airway management in the O.R., ICU and other settings. At some point, every intubation will be followed by an extubation. But what if the extubation has complications? Few anesthesiologists think about strategies for reintubation until problems have already begun to escalate. “Extubation has percolated into most airway guidelines at […]
Read MoreAuthors: Glenn S. Murphy, M.D. et al Anesthesiology 11 2018, Vol.129, 880-888. What We Already Know about This Topic: Monitoring of neuromuscular function recovery using quantitative methods improves patient outcome However, the application of quantitative monitoring is infrequent, in part because current devices are complex and application is time consuming What This Article Tells Us That […]
Read MoreAuthors: Rachael L. Bosma, Ph.D. et al Anesthesiology 11 2018, Vol.129, 1015-1024. What We Already Know about This Topic: Ketamine is an N-methyl-d-aspartate antagonist with growing use in the management of chronic pain Descending pain modulatory circuits are key modulators of chronic pain What This Article Tells Us That Is New: The infusion of ketamine resulted in […]
Read MoreAuthors: Laurent G. Glance, M.D. et al Anesthesiology 11 2018, Vol.129, 889-900. What We Already Know about This Topic: The Revised Cardiac Risk Index, and the risk calculators based on the National Surgical Quality Improvement Program can be used to assess the risk of cardiac adverse events after noncardiac surgery Recent clinical practice guidelines recommend the […]
Read MoreAuthor: Lee A. Fleisher, M.D. Anesthesiology 11 2018, Vol.129, 867-868. “[What are] the implications of advocating different risk algorithms on the decision for further diagnostic evaluation and potential interventional strategies[?]” THE preoperative evaluation of the patient has been a key function of anesthesiologists. The focus of the evaluation has been on identifying baseline comorbidities that will […]
Read MorePostoperative delirium affects a wide range of the general surgical population, with rates reported to be between 9 and 87 percent, depending on patient age and type of operative procedure. This adverse event has been associated with poor outcomes, such as increases in length of hospital stay, likelihood of being discharged to a rehabilitation center […]
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