From January 2007 through December 2016 there were more than 11,000 calls to US Poison Centers for paediatric exposures to buprenorphine, according to study published in Pediatrics. Most (86%) of the calls were about exposures among children aged younger than 6 years. Most (98%) buprenorphine exposures among younger children were unintentional. Nearly half (45%) of the […]
Read MorePeople who experience migraine earlier in life are more likely to develop depression, and vice versa, over the course of their lifetime. Migraine is “a common, multifactorial, disabling, recurrent, hereditary neurovascular headache disorder.”1 It affects 12% of US adults,2predominantly female — in fact, it affects 3 times as many women as men.3 The varying symptoms that […]
Read MorePerioperative lidocaine delivered intravenously (IV) may not improve pain, gastrointestinal recovery, postoperative nausea, or opioid consumption in the early postoperative phase compared with placebo or no treatment, according to results published in Cochrane Database of Systematic Reviews. The review included 68 trials with 4525 participants. Two trials compared IV lidocaine with thoracic epidural analgesia, and the […]
Read MoreLabor epidural analgesia may be associated with reduced likelihood of breastfeeding at 6 weeks, according to a study published in Anesthesia & Analgesia. The study included women intending to breastfeed who had delivered vaginally with or without labor epidural analgesia (n=1204). The researchers recorded breastfeeding at 3 days and 6 weeks postpartum. The primary outcome was breastfeeding at […]
Read MoreNew guidelines for the use of IV ketamine infusions for acute pain management have been published as a special article in Regional Anesthesia and Pain Medicine (2018;43[5]:456-466). The guidelines were jointly developed by the American Society of Regional Anesthesia and Pain Medicine (ASRA), the American Academy of Pain Medicine and the American Society of Anesthesiologists. “We have […]
Read MoreThe use of hypnosedation was found to be a useful alternative to general anesthesia in procedures involving cancer patients, according to French researchers. As an alternative to general anesthesia, hypnosedation is the combination of hypnosis, conscious sedation and local anesthesia. “By minimizing effects of anesthesia, this technique is particularly valuable for vulnerable patients. Hypnosis benefits […]
Read MoreAuthors: Firanescu CE et al. BMJ 2018 May 9 Vertebroplasty was no better than sham procedures in a randomized trial. In previous trials, vertebroplasty for pain relief has not outperformed sham procedures in patients with acute osteoporotic compression fractures (e.g., NEJM JW Gen Med Sep 1 2009 and N Engl J Med2009; 361:569 and 557). To address some methodological […]
Read MoreTranscutaneous electrical nerve stimulation (TENS) may represent an effective treatment for the prevention and management of migraine, according to a meta-analysis published in the Journal of Headache and Pain. Although promising, the findings presented by the researchers are based on low quality of evidence. TENS consists of the delivery of pulsed low-voltage electrical currents across the […]
Read MorePatients undergoing surgery for degenerative spondylolisthesis are more likely to have a dependency on opioid medications before surgery than afterward, according to research published in the Journal of Neurosurgery: Spine. For the study, Mayur Sharma, MD, Cleveland Clinic, Cleveland, Ohio, and colleagues analysed a database containing 10,708 patients who had undergone surgery for degenerative spondylolisthesis. The […]
Read MoreIntravenous (IV) acetaminophen does not meaningfully decrease opioid use following colorectal procedures, especially compared with oral acetaminophen, according to a study published in Anesthesiology. “With any new drug that is introduced to the US market, it is very important to monitor how it is used and if this results in the desired outcomes,” said Jashvant Poeran, […]
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