Month: October 2018

Uncategorized Published - 2 October, 2018    By - Dr Clemens
Non–steady State Modeling of the Ventilatory Depressant Effect of Remifentanil in Awake Patients Experiencing Moderate-to-severe Obstructive Sleep Apnea

Authors: Anthony G. Doufas, M.D., Ph.D. et al Anesthesiology published September 2018. What We Already Know about This Topic: Patients with obstructive sleep apnea are often said to have increased sensitivity to opioid-induced ventilatory depression What This Article Tells Us That Is New: The hypothesis that patients with moderate-to-severe obstructive sleep apnea are more sensitive to […]

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Uncategorized Published - 2 October, 2018    By - Dr Clemens
Oropharyngeal Bacterial Colonization after Chlorhexidine Mouthwash in Mechanically Ventilated Critically Ill Patients

Authors: Béatrice La Combe, M.D., M.Sc. et al Anesthesiology published September 2018. What We Already Know about This Topic: Chlorhexidine is frequently used to reduce oropharyngeal bacterial colonization in mechanically ventilated patients. How effective the drug is remains unclear. What This Article Tells Us That Is New: Bacterial colonization was evaluated in 30 mechanically ventilated patients […]

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Uncategorized Published - 2 October, 2018    By - Dr Clemens
Standardized Unloading of Respiratory Muscles during Neurally Adjusted Ventilatory Assist: A Randomized Crossover Pilot Study

Authors: Francesca Campoccia Jalde, M.D., Ph.D. et al Anesthesiology 10 2018, Vol.129, 769-777. What We Already Know about This Topic: Neurally adjusted ventilatory assist matches the mechanical pressure from the ventilator to the patient’s respiratory drive sensed from the electrical activity of the diaphragm, but the optimal degree of diaphragm unloading is uncertain What This Article […]

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Uncategorized Published - 1 October, 2018    By - Dr Clemens
Early Resumption of β Blockers Is Associated with Decreased Atrial Fibrillation after Noncardiothoracic and Nonvascular Surgery: A Cohort Analysis

Authors: Ashish K. Khanna, M.D., F.C.C.P., F.C.C.M. et al  Anesthesiology published October 8, 2018. What We Already Know about This Topic: Use of beta (β) blockers in the perioperative period is associated with reduced incidence of postoperative atrial fibrillation In chronic β-blocker users, optimal timing for β-blocker resumption in the postoperative setting is unclear What This […]

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Uncategorized Published - 1 October, 2018    By - Dr Clemens
Complications in Pediatric Regional Anesthesia: An Analysis of More than 100,000 Blocks from the Pediatric Regional Anesthesia Network

Authors: Benjamin J. Walker, M.D. et al Anesthesiology 10 2018, Vol.129, 721-732. What We Already Know about This Topic: Regional anesthesia is associated with a low but poorly quantified incidence of complications. What This Article Tells Us That Is New: In a prospective multicenter cohort of more than 100,000 blocks in children, there were no cases […]

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Uncategorized Published - 1 October, 2018    By - Dr Clemens
Anesthesia Care Team Composition and Surgical Outcomes

Authors: Eric C. Sun, M.D., Ph.D. et al Anesthesiology 10 2018, Vol.129, 700-709. What We Already Know about This Topic: Both nurse anesthetists and anesthesiologist assistants work together with physician anesthesiologists as part of care teams It is unknown whether the specific anesthesia care team composition (physician anesthesiologist plus nurse anesthetist or anesthesiologist assistant) is associated […]

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Uncategorized Published - 1 October, 2018    By - Dr Clemens
Liposomal Bupivacaine Does Not Reduce Inpatient Opioid Prescription or Related Complications after Knee Arthroplasty: A Database Analysis

Authors: Lukas Pichler, M.D. et al Anesthesiology 10 2018, Vol.129, 689-699. What We Already Know about This Topic: The need for long-duration nonopioid pain relief after total knee arthroplasty has driven multimodal analgesic regimens, some of which include the administration of liposomal bupivacaine It is unclear whether the use of liposomal bupivacaine is reliably associated with […]

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Uncategorized Published - 1 October, 2018    By - Dr Clemens
Supervised Machine-learning Predictive Analytics for Prediction of Postinduction Hypotension

Authors: Samir Kendale, M.D. et al  Anesthesiology 10 2018, Vol.129, 675-688. What We Already Know about This Topic: The ability to predict postinduction hypotension remains limited and challenging due to the multitude of data elements that may be considered Novel machine-learning algorithms may offer a systematic approach to predict postinduction hypotension, but are understudied What This […]

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Uncategorized Published - 1 October, 2018    By - Dr Clemens
Development and Validation of a Deep Neural Network Model for Prediction of Postoperative In-hospital Mortality

Authors: Christine K. Lee, M.S., Ph.D. et al    Anesthesiology 10 2018, Vol.129, 649-662. What We Already Know about This Topic: Robust predictions are required to compare perioperative mortality among hospitals Deep neural network systems, a type of machine learning, can be used to develop highly nonlinear prediction models What This Article Tells Us That Is […]

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