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Authors: Thomas K. Henthorn, M.D. et al Anesthesiology 8 2018, Vol.129, 260-270. What We Already Know about This Topic: Recirculatory pharmacokinetic models describe intravascular mixing by incorporating cardiac output and its distribution to characterize the oscillations of arterial and venous drug concentrations in the minutes after rapid IV drug administration Arterial drug concentrations during a drug […]
Read MoreIt’s time for us all to face a hard truth: you can, in fact, compare apples and oranges. Really, they’re not all that dissimilar. The fundamental traits of each are pretty much the same: they’re both spherical fruits and they both can be made into delicious candy. By almost any measure, they’re much more similar […]
Read MoreRadiofrequency ablation of the basivertebral nerve may lead to significant short-term reduction in pain and functional disability in patients with chronic low back pain and type I or type II Modic changes of the vertebral bodies, according to findings from a randomized trial published in the European Spine Journal. The investigators targeted the basivertebral nerve in […]
Read MoreAuthors: Phi T. Ho, M.D., M.B.A. et al Anesthesiology 8 2018, Vol.129, 249-259. What We Already Know about This Topic: Prompt availability of dantrolene is important for treating malignant hyperthermia and has resulted in lowered mortality rates Maintaining a malignant hyperthermia cart and full treatment dose of dantrolene is expensive, particularly for locations with low incidence […]
Read MoreAuthors: Gianluca Cappelleri, M.D. et al Anesthesiology 8 2018, Vol.129, 241-248. What We Already Know about This Topic: Reducing the volume of local anesthetic administered for neural blockade may increase safety Local anesthetic administration can result in nerve damage What This Article Tells Us That Is New: The low volume intraneural injection of ropivacaine 1% provided […]
Read MoreAuthors: Takeshi Yoshida, M.D., Ph.D. et al Anesthesiology 7 2018, Vol.129, 163-172. Background: In supine patients with acute respiratory distress syndrome, the lung typically partitions into regions of dorsal atelectasis and ventral aeration (“baby lung”). Positive airway pressure is often used to recruit atelectasis, but often overinflates ventral (already aerated) regions. A novel approach to selective recruitment […]
Read MoreIn a study of patients undergoing corrective osteotomy for hallux valgus, those who received an ankle block with a mixture of bupivacaine and long-acting liposomal bupivacaine (Exparel, Pacira) experienced relief of postoperative pain and a marked reduction in opioid consumption, compared with use of general anesthesia alone or ankle block with bupivacaine alone. Both types […]
Read MoreThere are general risks when it comes to going under the knife, many of them related to general anesthesia—side effects from shivering to vomiting. Perhaps more unsettling for the patient, however, can be states of confusion in the minutes and hours after surgery, or even the long-term memory loss sometimes seen in senior patients. “The […]
Read MoreThe management of pulmonary hypertension and right ventricular dysfunction in critically ill patients presents many challenges, but current evidence suggests several clear and effective approaches. According to a systematic review of the literature, use of vasopressors had a moderate to high level of supporting evidence. Studies invest igating inotropic drugs and pulmonary vasodilators also demonstrated […]
Read MoreLidocaine gel may not provide substantial advantage over nonanesthetic gel for reducing pain associated with transurethral bladder catheterization in children age <4 years, according to a meta-analysis published in the Annals of Emergency Medicine. In this study, 2 investigators independently reviewed randomized controlled trials comparing the pain-relieving efficacy of lidocaine gel vs nonanesthetic gel in pediatric patients undergoing […]
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