Month: April 2018

Uncategorized Published - 6 April, 2018    By - Dr Clemens
Comparison of Two Major Perioperative Bleeding Scores for Cardiac Surgery Trials: Universal Definition of Perioperative Bleeding in Cardiac Surgery and European Coronary Artery Bypass Grafting Bleeding Severity Grade

Authors: Justyna Bartoszko, M.D. et al Anesthesiology March 2018. Background: Research into major bleeding during cardiac surgery is challenging due to variability in how it is scored. Two consensus-based clinical scores for major bleeding: the Universal definition of perioperative bleeding and the European Coronary Artery Bypass Graft (E-CABG) bleeding severity grade, were compared in this substudy of […]

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Uncategorized Published - 6 April, 2018    By - Dr Clemens
Amisulpride Prevents Postoperative Nausea and Vomiting in Patients at High Risk: A Randomized, Double-blind, Placebo-controlled Trial

Authors: Peter Kranke, M.D., M.B.A. et al Anesthesiology published on March 2018 Background: Postoperative nausea and vomiting causes distress for patients and can prolong care requirements. Consensus guidelines recommend use of multiple antiemetics from different mechanistic classes as prophylaxis in patients at high risk of postoperative nausea and vomiting. The prophylactic efficacy of the dopamine D2/D3 antagonist amisulpride […]

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Uncategorized Published - 6 April, 2018    By - Dr Clemens
Effects of Prone Positioning on Transpulmonary Pressures and End-expiratory Volumes in Patients without Lung Disease

Authors: Abirami Kumaresan, M.D. et al Anesthesiology Newly Published on March 8, 2018. Background: The effects of prone positioning on esophageal pressures have not been investigated in mechanically ventilated patients. Our objective was to characterize effects of prone positioning on esophageal pressures, transpulmonary pressure, and lung volume, thereby assessing the potential utility of esophageal pressure measurements in […]

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Uncategorized Published - 6 April, 2018    By - Dr Clemens
Opioids No Better Than Nonopioids for Easing Common Types of Chronic Pain

Author: Lorenzo Di Francesco, MD, FACP, FHM Opioids are not better than nonopioid drugs for relieving back pain or pain related to hip or knee osteoarthritis, a JAMA study finds. Nearly 250 patients with moderate-to-severe chronic back pain or hip or knee osteoarthritis pain were randomized to receive either opioids or nonopioids. In the opioid group, patients […]

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Uncategorized Published - 6 April, 2018    By - Dr Clemens
Hyperinsulinemic Normoglycemia during Cardiac Surgery Reduces a Composite of 30-day Mortality and Serious In-hospital Complications: A Randomized Clinical Trial

Authors: Andra E. Duncan, M.D. et al Anesthesiology published on March 2018 Background: Hyperinsulinemic normoglycemia augments myocardial glucose uptake and utilization. We tested the hypothesis that hyperinsulinemic normoglycemia reduces 30-day mortality and morbidity after cardiac surgery. Methods: This dual-center, parallel-group, superiority trial randomized cardiac surgical patients between August 2007 and March 2015 at the Cleveland Clinic, Cleveland, Ohio, […]

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Uncategorized Published - 5 April, 2018    By - Dr Clemens
Dopamine D2-receptor Antagonist Droperidol Deepens Sevoflurane Anesthesia

Authors: Ryuhei Araki, M.D. et al Anesthesiology 4 2018, Vol.128, 754-763. Background: Although midbrain dopaminergic pathways are known to contribute to arousal and emergence from anesthesia, few reports exist regarding the anesthetic effects of dopamine D2 receptor antagonism in humans. This study examined the effect of the D2 receptor antagonist droperidol on sevoflurane anesthesia by examining α […]

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Uncategorized Published - 5 April, 2018    By - Dr Clemens
Effect of Epidural Infusion Bolus Delivery Rate on the Duration of Labor Analgesia: A Randomized Clinical Trial

Authors: Elizabeth M. S. Lange, M.D. et al     Author Notes Anesthesiology 4 2018, Vol.128, 745-753. Background: Programmed intermittent boluses of local anesthetic have been shown to be superior to continuous infusions for maintenance of labor analgesia. High-rate epidural boluses increase delivery pressure at the catheter orifice and may improve drug distribution in the epidural space. We hypothesized […]

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Uncategorized Published - 5 April, 2018    By - Dr Clemens
Orthopedic, anesthesia providers settle false claims allegations for $3.2M

Newnan-based Georgia Bone & Joint, Summit Orthopaedic Surgery Center, Southern Crescent Anesthesiology medical group, Sentry Anesthesia Management, as well as certified registered nurse anesthetist David LaGuardia, agreed to pay the federal government $3.2 million to resolve alleged violations of the False Claims Act, according to the Department of Justice. The government alleged Mr. LaGuardia, Sentry and SCA […]

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Uncategorized Published - 5 April, 2018    By - Dr Clemens
Doctors sound the alarm on “opioid alternative” gabapentin

A drug that has been touted as a safe alternative to opioid painkillers is now on the radar of health officials and law enforcement officials as it is being found in more and more overdose deaths. Gabapentin is a nerve pain medication that is typically used to treat seizures and pain associated with shingles. But amid the opioid epidemic that has ripped through […]

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Uncategorized Published - 5 April, 2018    By - Dr Clemens
Gluten-Free Diet May Relieve Peripheral Neuropathic Pain

For patients with gluten neuropathy, following a strict gluten-free diet is associated with significantly reduced odds of peripheral neuropathic pain, according to a study scheduled for presentation at the upcoming annual meeting of the American Academy of Neurology, to be held from April 21 to 27 in Los Angeles. Panagiotis Zis, MD, PhD, from the […]

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