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Authors: Per Ederoth, M.D., Ph.D. et al Anesthesiology 4 2018, Vol.128, 710-717. Background: Acute kidney injury is a common complication after cardiac surgery, leading to increased morbidity and mortality. One suggested cause for acute kidney injury is extracorporeal circulation–induced ischemia–reperfusion injury. In animal studies, cyclosporine has been shown to reduce ischemia–reperfusion injury in the kidneys. We hypothesized […]
Read MoreAuthors: David O. Warner, M.D. et al Anesthesiology4 2018, Vol.128, 700-703. “The potential for adverse neurodevelopmental effects of anesthetics is clearly a complex problem and the answers are not ‘obvious’…[and] we grapple with the specific question of whether animal findings translate to children…” EXPOSURE of young animals to most clinically-utilized anesthetics in sufficient doses changes […]
Read MoreAuthors: Semler MW et al. N Engl J Med 2018 Mar 1. Acutely hospitalized patients had better outcomes with lactated Ringer’s solution than with normal saline. What is the right crystalloid for fluid resuscitation? Because limited data guide this decision, choices traditionally have been driven by culture: saline in medical units, and lactated Ringer’s solution for surgical […]
Read MoreAuthor: Jenifer Lightdale, MD, MPH A meta-analysis of 13 randomized controlled trials shows clear and consistent evidence of a decrease in respiratory compromise with capnography monitoring. Clinically significant adverse events associated with procedural sedation and analgesia (PSA)—including critical oxygen desaturation, bradycardia, hypotension and cardiac arrest—are relatively uncommon. However, their occasional occurrence should be recognized as […]
Read MoreArticle I wanted to share with our readers. BY Karen Feldscher Harvard Chan School Communications DATE March 13, 2018 A Harvard study has found that physicians’ salaries and hospital services are in part what’s behind the higher costs of U.S. health care. In 2016, the U.S. spent nearly twice as much on health care as other […]
Read MoreI thought this was something we should know so we can share with our surgeons. Findings from an analysis that included more than 200,000 patients who underwent common surgical procedures suggests that the optimal length of opioid pain prescriptions is 4 to 9 days for general surgery procedures, 4 to 13 days for women’s health […]
Read MorePostoperative myocardial injury is correlated with increasing resting preoperative heart rate in noncardiac surgery patients, according to a new study. Interestingly, the researchers concluded that the relationship may be J-shaped instead of linear, demonstrating that abnormally low heart rates may be potentially dangerous, too. “One of the theories about myocardial injury is that heart rate, […]
Read MoreThis is for our readers who treat ICU patients Patients receiving low-dose dexmedetomidine report no changes in sleep quality Low-dose dexmedetomidine significantly reduces delirium in critically ill adults, according to a study published online March 2 in the American Journal of Respiratory and Critical Care Medicine. Yoanna Skrobik, M.D., from McGill University in Montreal, and colleagues […]
Read MoreI thought this was interesting so I wanted to share it with our readers. Women with a high level of cardiovascular fitness at midlife may have a reduced risk for dementia years later, a Neurology study suggests. Nearly 200 Swedish women aged 38 to 60 underwent a cycling test that measured cardiovascular fitness based on maximal exertion […]
Read MoreAuthors: Hansen M et al. Circulation 2018 Mar 6. Each 1-minute delay in epinephrine administration was associated with lower survival to hospital discharge. Epinephrine is a standard part of cardiac arrest algorithms for patients with nonshockable rhythms and is given by emergency medical services (EMS) crews to patients who suffer out-of-hospital cardiac arrest (OHCA). These authors reviewed […]
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