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Authors: Molly P. Jarman, PhD et al JAMA Surg.published February 7, 2018. Question What is the association of injury incident location characteristics with mortality? Findings This cross-sectional study of 16 082 adults found an 8% increase in the odds of death for every 5-mile increase in distance to the nearest trauma center and an 3% increased odds of death for […]
Read MoreAuthors: Alexander J. Butwick, M.B.B.S., F.R.C.A.; et al Anesthesiology 4 2018, Vol.128, 774-783. Background: It is unclear whether obesity is a risk factor for postpartum hemorrhage. The authors hypothesized that obese women are at greater risk of hemorrhage than women with a normal body mass index. Methods: The authors conducted a cohort study of women who underwent delivery […]
Read MoreAuthors: Hagen Bomberg, M.D. et al Anesthesiology 4 2018, Vol.128, 764-773. Background: Prolonged catheter use is controversial because of the risk of catheter-related infection, but the extent to which the risk increases over time remains unknown. We thus assessed the time-dependence of catheter-related infection risk up to 15 days. Methods: Our analysis was based on the German Network […]
Read MoreAuthors: Daniel I. McIsaac, M.D., M.P.H., F.R.C.P.C. et al Anesthesiology 3 2018, Vol.128, 480-491. Background: There is consistent and significant variation in neuraxial anesthesia use for hip fracture surgery across jurisdictions. We measured the association of hospital-level utilization of neuraxial anesthesia, independent of patient-level use, with 30-day survival (primary outcome) and length of stay and costs (secondary […]
Read MoreAuthors: Ryuhei Araki, M.D.et al Anesthesiology 4 2018, Vol.128, 754-763. Background: Although midbrain dopaminergic pathways are known to contribute to arousal and emergence from anesthesia, few reports exist regarding the anesthetic effects of dopamine D2 receptor antagonism in humans. This study examined the effect of the D2 receptor antagonist droperidol on sevoflurane anesthesia by examining α and […]
Read MoreAuthors: Elizabeth M. S. Lange, M.D. et al Anesthesiology 4 2018, Vol.128, 745-753 Background: Programmed intermittent boluses of local anesthetic have been shown to be superior to continuous infusions for maintenance of labor analgesia. High-rate epidural boluses increase delivery pressure at the catheter orifice and may improve drug distribution in the epidural space. We hypothesized that high-rate […]
Read MoreAuthors: Rebecca Y. Klinger, M.D., M.S. et al Anesthesiology 4 2018, Vol.128, 728-744. Background: Amyloid deposition is a potential contributor to postoperative cognitive dysfunction. The authors hypothesized that 6-week global cortical amyloid burden, determined by 18F-florbetapir positron emission tomography, would be greater in those patients manifesting cognitive dysfunction at 6 weeks postoperatively. Methods: Amyloid deposition was evaluated in cardiac […]
Read MoreAuthors: In-Kyung Song, M.D. et al Anesthesiology 4 2018, Vol.128, 718-727. Background: Pediatric cardiac patients are at risk for perioperative respiratory insufficiency. The objective of this study was to assess the utility of perioperative lung ultrasound examination in pediatric cardiac surgery. Methods: In this randomized, controlled trial, children (5 yr old or younger) undergoing cardiac surgery were allocated into […]
Read MoreThis is an article that I bet our male followers will be happy to read. Digital rectal examination (DRE) for prostate cancer screening in primary care should be discouraged given “the lack of evidence supporting its use,” according to a meta-analysis. The analysis encompassed seven studies measuring the effectiveness of DRE in screening for prostate […]
Read MoreAuthors: Deborah J. Culley, M.D. et al Anesthesiology 4 2018, Vol.128, 697-699. “…[T]here may be risk associated with exposure to general anesthesia…[but] surgery without adequate anesthesia and analgesia is simply not an option.” TWENTY-FIVE years ago, surgery was commonly performed on awake or paralyzed infants and children without the benefit of analgesics, sedatives, or anesthetics. This […]
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