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AUTHORS: Dam, Mette MD et al Anesthesia & Analgesia: July 2017 – Volume 125 – Issue 1 – p 303–312 BACKGROUND: The spread of injectate resulting from a transmuscular quadratus lumborum (TQL) block and a transverse oblique paramedian (TOP) TQL block has never been examined. The aim of this cadaveric study was to investigate by which […]
Read MoreWhen it comes to surgery for patients with hip fractures, earlier is better. A database analysis by a team of Cleveland Clinic researchers concluded that for every 10-hour increase in time from hospital admission to surgery, one-year mortality in these patients increased by 5%. “There is considerable debate regarding the timing of surgery after hip […]
Read MoreAnesthesiology · March 2, 2017 Background: Multimodal analgesia is standard practice for total knee arthroplasty; however, the role of regional techniques in improved perioperative outcomes remains unknown. The authors hypothesized that peripheral nerve blockade would result in lower pain scores and opioid consumption than two competing periarticular injection solutions. Methods: This three-arm, nonblinded trial randomized 165 adults undergoing unilateral […]
Read MoreThe dose of local anesthetic used in spinal-epidural analgesia for external cephalic version has no influence on the success rate of the procedure, according to a randomized controlled trial. The conclusion contradicts earlier meta-analyses. Although the trial investigators found dose-dependent changes in some secondary outcomes, they noted that these results highlight the importance of blinding […]
Read MoreDespite the common use of opioid analgesics in the management of chronic pain, no factors have been identified that could predict optimal efficacy of these agents. A study published in the March 2017 issue of Pain showed that psychosocial variables such as depression and anxiety predict the response to morphine analgesia in patients with low back pain […]
Read MoreAnesthesiologists must be key participants in the process of reducing surgical site infections, including ensuring that the correct prophylactic antimicrobial therapy is given 30 to 60 minutes before incision. This is just one of many updated SSI guidelines that were recently published in the Journal of the American College of Surgeons (2017;224:59-74). “Anesthesiologists need to embrace their […]
Read MoreAuthors: Matthieu Biais, M.D., Ph.D. et al Anesthesiology published on June 22, 2017 Background: Mini-fluid challenge of 100 ml colloids is thought to predict the effects of larger amounts of fluid (500 ml) in intensive care units. This study sought to determine whether a low quantity of crystalloid (50 and 100 ml) could predict the effects of […]
Read MoreAuthors: László Asztalos, M.D. et al Anesthesiology published on June 22, 2017 Background: Rocuronium-induced neuromuscular block that spontaneously recovered to a train-of-four count of four can be reversed with sugammadex 0.5 or 1.0 mg/kg. We investigated whether these doses of sugammadex can also reverse vecuronium at a similar level of block. Methods: Sixty-five patients were randomly assigned, and […]
Read MoreAuthors: Karim Asehnoune, M.D., Ph.D. et al Anesthesiology published on June 22, 2017 Background: Patients with brain injury are at high risk of extubation failure. Methods: We conducted a prospective observational cohort study in four intensive care units of three university hospitals. The aim of the study was to create a score that could predict extubation success in […]
Read MoreA weekly injectable depot formulation of buprenorphine may be effective in treating opioid use disorder, according to a small, industry-funded, phase II trial published in JAMA Psychiatry. Currently, sublingual buprenorphine can be diverted and misused. Fifty patients with opioid use disorder who weren’t seeking treatment were randomized to receive two 24- or 32-mg doses of injectable […]
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