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A new study found that preoperative chronic opioid use leads to more adverse events, but is tapering or stopping opioids before surgery the solution? PPM experts say perhaps not. Interviews with Jennifer P. Schneider, MD, PhD, Jeffrey Gudin, MD, and Ofer Wellisch, MD Patients receiving opioids prior to elective abdominal surgery had slightly longer hospital stays and […]
Read MoreAuthors: Eunsu Kang et al BMC Anesthesiol. 2016;16(116) A Randomized Controlled Trial Background: Dexmedetomidine, a selective alpha-2 agonist, has sedative, analgesic, and anxiolytic effects without respiratory depression. Dexmedetomidine can cause a biphasic cardiovascular response, and induce transient hypertension. Hypotension is a common complication of spinal anesthesia. Decreasing anxiety of patients before procedure is important for high quality […]
Read MoreAUTHORS: Zeidan, Ahed M. MD et al Anesthesia & Analgesia: April 2017 – Volume 124 – Issue 4 – p 1168–1173 BACKGROUND: We tested the hypothesis whether gender differences exist in the applied cricoid force necessary to prevent regurgitation. Real-time visual and dynamic means were used to assess the effectiveness of different applied cricoid forces in […]
Read MoreAUTHORS: Zhou, Jing MD, PhD et al Anesthesia & Analgesia: February 2017 – Volume 124 – Issue 2 – p 465–471 BACKGROUND: Although the bronchodilatory actions of volatile anesthetics, such as halothane, isoflurane, and sevoflurane, have been well documented in previous studies, the properties of desflurane remain controversial. The aim of this study was to investigate […]
Read MoreAuthors: Chau, Anthony MD, MMSc, FRCPC et al Anesthesia & Analgesia: February 2017 – Volume 124 – Issue 2 – p 560–569 Obstetric Anesthesiology: Original Clinical Research Report BACKGROUND: The dural puncture epidural (DPE) technique is a modification of the combined spinal epidural (CSE) technique, where a dural perforation is created from a spinal needle but […]
Read MoreAuthors: Toyoaki Maruta et al BMC Anesthesiol. 2016;16(110) A Prospective Randomised Single-Centre Study Background: Remifentanil is an effective drug for protecting against adverse haemodynamic responses to tracheal intubation. We compared the haemodynamic responses during anaesthesia induction between continuous intravenous (IV) infusion and two bolus injections of remifentanil. Methods: This prospective, randomised, open-label, single-centre study included patients with American […]
Read MoreAUTHORS: Kram, Bridgette PharmD et al Anesthesia & Analgesia: March 2017 – Volume 124 – Issue 3 – p 782–788 BACKGROUND: The purpose of this study was to determine whether mechanically ventilated trauma patients with a positive urine drug screen (UDS) for cocaine and/or amphetamines have different opioid analgesic and sedative requirements compared with similar patients […]
Read MoreAuthors: Roshanov PS et al. Anesthesiology 2017 Jan. In an observational study, withholding angiotensin-converting–enzyme inhibitors was associated with fewer adverse events. For patients who take angiotensin-converting–enzyme (ACE) inhibitors and undergo noncardiac surgery, some observational studies suggest that continuing the ACE inhibitors on the morning of surgery is associated with excess risk for intraoperative hypotension. However, the […]
Read MoreSurgery patients with migraine are at increased risk for ischemic stroke in the perioperative period and hospital readmission within 30 days of discharge, a hospital registry study suggests. “Migraine should be incorporated in the assessment for risk of perioperative stroke,” Matthias Eikermann, MD, PhD, from Massachusetts General Hospital and Harvard Medical School in Boston, told Medscape […]
Read MoreAUTHORS: Grigg, Eliot B. MD et al Anesthesia & Analgesia: May 2017 – Volume 124 – Issue 5 – p 1617–1625 BACKGROUND: Medication errors continue to be a significant source of patient harm in the operating room with few concrete countermeasures. The organization and identification of medication syringes may have an impact on the commission of […]
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