Month: April 2017

Uncategorized Published - 4 April, 2017    By - Dr Clemens
Sedation of Patients With Disorders of Consciousness During Neuroimaging: Effects on Resting State Functional Brain Connectivity

AUTHORS: Kirsch, Muriëlle MD et al Anesthesia & Analgesia: February 2017 – Volume 124 – Issue 2 – p 588–598 BACKGROUND: To reduce head movement during resting state functional magnetic resonance imaging, post-coma patients with disorders of consciousness (DOC) are frequently sedated with propofol. However, little is known about the effects of this sedation on the […]

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Uncategorized Published - 4 April, 2017    By - Dr Clemens
Prediction of Opioid Analgesic Efficacy by Measurement of Pupillary Unrest

AUTHORS: Neice, Andrew E. MD et al Anesthesia & Analgesia: March 2017 – Volume 124 – Issue 3 – p 915–921 BACKGROUND: Pupillary unrest under ambient light (PUAL) is the fluctuation in pupil diameter in time around a mean value. PUAL is augmented by light and diminished by administration of opioids. We hypothesized that, because pupillary […]

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Uncategorized Published - 4 April, 2017    By - Dr Clemens
Comparison Between Retrograde and Antegrade Peripheral Venous Cannulation in Intensive Care Unit Patients: Assessment of Thrombus Formation.

AUTHORS: Abdelaal Ahmed Mahmoud et al Anesthesia & Analgesia: December 8, 2016 BACKGROUND: Antegrade cannulation of peripheral veins is the usual practice. Blood stasis between a catheter and the wall of the vein or at its tip in addition to catheter-induced phlebitis may initiate a thrombosis. The use of retrograde ventriculojugular shunts against the direction of […]

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Uncategorized Published - 4 April, 2017    By - Dr Clemens
Epidural Local Anesthetics Versus Opioid-Based Analgesic Regimens for Postoperative Gastrointestinal Paralysis, Vomiting, and Pain After Abdominal Surgery: A Cochrane Review

AUTHORS: Guay J et al Anesthesia & Analgesia 123 (6), 1591-1602 (Dec 2016) BACKGROUND The aim of this review was to compare the effects of postoperative epidural analgesia with local anesthetics to postoperative systemic or epidural opioids in terms of return of gastrointestinal transit, postoperative pain control, postoperative vomiting, incidence of gastrointestinal anastomotic leak, hospital […]

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Uncategorized Published - 3 April, 2017    By - Dr Clemens
A Novel Approach for the Control of Inflammatory Pain: Prostaglandin E2 Complexation by Randomly Methylated -Cyclodextrins

AUTHORS: Sauer, Reine-Solange PhD et al Anesthesia & Analgesia: February 2017 – Volume 124 – Issue 2 – p 675–685 BACKGROUND: Inhibitors of cyclooxygenase, which block the formation of prostaglandin (PG) E2, are the standard treatment of inflammatory pain. These drugs, however, have serious gastrointestinal, renal, and cardiovascular side effects that limit their clinical use. Cyclodextrins […]

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Uncategorized Published - 3 April, 2017    By - Dr Clemens
Seronegative RA and Fibromyalgia May Be Linked

Seronegative rheumatoid arthritis (RA) is strongly associated with fibromyalgia, according to a newly published study. However, one expert suggests the difference seen between seronegative vs seropositive RA and fibromyalgia might reflect the greater scrutiny of patients with seronegative RA in typical clinical practice. Jayanth Doss, MD, from the Division of Rheumatology and Immunology, Duke University, […]

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Uncategorized Published - 3 April, 2017    By - Dr Clemens
Fibromyalgia: CBT/Exercise Training May Get Teens Moving

Routine physical exercise is an important factor in managing widespread musculoskeletal pain in conditions such as fibromyalgia (FM), but patients may fear that such exertion will worsen pain. Now, results of a pilot study suggest that a combination of cognitive behavioral therapy (CBT) that emphasizes pain coping strategies and a specially tailored exercise program reduces […]

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Uncategorized Published - 3 April, 2017    By - Dr Clemens
Pregabalin Relieves Pain in Some Patients With Fibromyalgia

Only a minority of patients with moderate to severe fibromyalgia get pain relief from the antiepileptic pregabalin, but the quality of that pain relief is strong, an updated review of the related literature concludes. “Pregabalin works extraordinarily well in 1 person in 10 who has fibromyalgia and it doesn’t work for the other 9 patients, […]

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Uncategorized Published - 3 April, 2017    By - Dr Clemens
Fibromyalgia: Evidence-Based Management

Hello. I am Dr Jonathan Kay, the Timothy S. and Elaine L. Peterson Chair in Rheumatology, and professor of medicine at the University of Massachusetts Medical School. Welcome to my Medscape blog. Fibromyalgia is a label that is a challenge for primary care physicians and other physicians alike. Patients present with generalized pain, fatigue, and […]

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