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Authors: Chunhua Xi, M.D. et al Anesthesiology published on March 2, 2017. Background: It has been demonstrated that κ-opioid receptor agonists can reduce hypoxia–ischemia brain injury in animal models. However, it is unclear how the κ-opioid receptor responds to hypoxia–ischemia. In the current study, the authors used an in vitro model of oxygen–glucose deprivation and […]
Read MoreWhen a patient catastrophizes their chronic pain, symptoms could begin to interfere with their daily life, and teenagers may be the most vulnerable to this problem. By Thomas G. Ciccone Interview with Amanda B. Feinstein, PhD Adolescence is a difficult time for most children—but with chronic pain involved, it could be especially hard. In a study […]
Read MoreThe most significant way to improve care of patients with complex regional pain syndrome is with an early diagnosis. By Gary W. Jay, MD Complex regional pain syndrome (CRPS) is a heterogeneous group of disorders that generally develop after trauma to soft tissue but also may develop after visceral diseases or nerve lesions, or rarely without […]
Read MoreNew epidemiological data suggests patients suffering from chronic osteomyelitis (COM), which causes chronic inflammation, may be at increased risk of being diagnosed with fibromyalgia (FM). By Thomas G. Ciccone Interview with Don L. Goldenberg, MD A recent study suggests chronic osteomyelitis (COM) could be a risk factor for developing fibromyalgia (FM). COM is a condition marked by […]
Read MoreThe ACP’s new guidelines support the use of nonpharmacologic therapies, such as chiropractic and acupuncture, as first-line options for treating nonspecific low back pain. By Thomas G. Ciccone Interviews with Nitin S. Damle, MD, MS, MACP, John Garzione, PT, DPT, William Lauretti, DC The American College of Physicians (ACP) is making a strong push for the […]
Read MoreEvaluating oral fluids rather than urine samples revealed that hydrocodone is an important metabolite of codeine, which may be useful in monitoring medication use by pain patients and for drug testing. By Christine Rhodes Interviews with Maria Guevara, PharmD, and Michael Gabay, PharmD, JD The presence of hydrocodone in oral fluids may be used to improve confirmation of […]
Read MoreThe elderly pain population presents many challenges for pain practitioners, including comorbid medical conditions, polypharmacy, and declining physical and mental function. Learn more about how to manage this challenging age group. Authors: Robert J. Gatchel, PhD, ABPP et al Pain and pain management are a growing concern among Americans age 65 and older.1 A recent analysis […]
Read MoreAnesthesia investigators who worry about obtaining patient consent for clinical trials—on the day of surgery—finally might be able to lay those fears to rest, a new study suggests. Obtaining same-day consent has become an issue at several medical centers around the country since the elimination of preoperative clinics due to cost constraints. Opportunities are often […]
Read MoreWhat place do case reports have in the anesthesia literature? According to research, their impact is significant, being regularly cited in review articles and even clinical guidelines. Even so, the quality of such reports needs improvement, and their worth can be gauged by implementation of the Case Report (CARE) guidelines (www.care-statement.org). “Case reports have always […]
Read MoreFailure to achieve first-attempt success during intubation using a video laryngoscope is associated with higher odds of adverse events in the ICU, according to a recent study. First-attempt success should be the goal of emergency airway management, regardless of location or device used, the researchers said. “First-attempt success isn’t a patient-centered outcome, but it is […]
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