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The frequency of sickle cell-related pain crises (SCPC) is reduced significantly by high-dose SelG1 among patients with sickle cell disease, with or without hydroxyurea treatment, according to a study presented here at the 2016 Annual Meeting of the American Society of Hematology (ASH). SelG1 is a P-selectin inhibitor, said Kenneth I. Ataga, MD, University of […]
Read MoreThe most important thing a health care provider can do is recognize sepsis and septic shock early and take immediate action, according to new guidelines released at the Society of Critical Care Medicine’s (SCCM) 46th Critical Care Congress. “I think it is important to recognize that sepsis and septic shock are medical emergencies,” said Andrew Rhodes, FRCP, […]
Read MoreSending patients with obstructive sleep apnea (OSA) who are undergoing endoscopic sinus surgery (ESS) to the ICU for intensive monitoring during the first postoperative night improves respiratory complication–related outcomes, a new study has found. Patients with OSA have a higher incidence of postoperative respiratory complications, according to researchers from Jikei University, in Tokyo. Certain procedures, […]
Read MoreNationwide efforts to make health care safer are paying off, according to a report released by the Department of Health and Human Services (HHS). Thanks, in part, to provisions of the Affordable Care Act (ACA), approximately 125,000 fewer patients died due to hospital-acquired conditions (HACs), and more than $28 billion in health care costs were […]
Read MoreCanadian Journal of Anesthesia April 2017, Volume 64, Issue 4, pp 416–427 Authors: David T. Wong Purpose During the process of tracheal intubation, patients are apneic or hypoventilating and are at risk of becoming hypoxemic. This risk is especially high in patients with acute or chronic respiratory failure and accompanying compromised respiratory reserve. To address this concern, apneic oxygenation can be […]
Read MoreA single glucocorticoid injection offers short-term relief of chronic back pain associated with discopathy, according to a study in the Annals of Internal Medicine. But the benefits are not long-lasting. Some 135 patients with daily low back pain of at least 3 months’ duration and active discopathy on magnetic resonance imaging were randomized to receive either […]
Read MoreAuthorizing a second opioid prescription in opioid-naive adults doubles the risk for chronic opioid use, according to an MMWR study. Researchers examined a sample of 1.3 million U.S. adults who were prescribed opioids for the first time between 2006 and 2015. Of these, the probability of continued opioid use 1 year later was 6%, and 3 years […]
Read MorePresented at the Society for Academic Emergency Medicine conference, May 2016, New Orleans, LA. Authors: Cameron P. Upchurch, BS et al Study objective Induction doses of etomidate during rapid sequence intubation cause transient adrenal dysfunction, but its clinical significance on trauma patients is uncertain. Ketamine has emerged as an alternative for rapid sequence intubation induction. […]
Read MoreAuthors: Chalifoux, F., Colin, F., St-Pierre, P. et al. Can J Anesth/J Can Anesth (2017) 64: 280 Background Although intravenous dexamethasone prolongs the analgesic duration of interscalene brachial plexus block, it is uncertain whether this effect can be observed using lower doses of dexamethasone. This study evaluated the impact of intravenous dexamethasone (4 mg and […]
Read MoreAuthors: Motov S et al., Am J Emerg Med 2017 Mar 3; Neuropsychiatric side effects were more common with intravenous push administration, but does it matter? At intravenous (IV) doses of 0.1–0.3 mg/kg, ketamine is a safe and effective analgesic. Adverse effects are minimal and include sedation and a feeling of disconnection from reality. Investigators compared the effectiveness […]
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