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Authors: Mathieu Raux, M.D., Ph.D. et al Anesthesiology 3 2017, Vol.126, 522-533. Background: Initial blood lactate and base deficit have been shown to be prognostic biomarkers in trauma, but their respective performances have not been compared. Methods: Blood lactate levels and base deficit were measured at admission in trauma patients in three level 1 trauma centers. This […]
Read MoreAuthors: Leanne Clifford, B.M. et al Anesthesiology 3 2017, Vol.126, 409-418 Background: Transfusion-associated circulatory overload remains underappreciated in the perioperative environment. The authors aimed to characterize risk factors for perioperative transfusion-associated circulatory overload and better understand its impact on patient-important outcomes. Methods: In this case–control study, 163 adults undergoing noncardiac surgery who developed perioperative transfusion-associated circulatory overload were […]
Read MoreAuthors: Michael R. Mathis, M.D. et al Anesthesiology 3 2017, Vol.126, 450-460. Background: Patients with left ventricular assist devices presenting for noncardiac surgery are increasingly commonplace; however, little is known about their outcomes. Accordingly, the authors sought to determine the frequency of complications, risk factors, and staffing patterns. Methods: The authors performed a retrospective study at their […]
Read MoreAuthors: Rhodes A et al., Intensive Care Med 2017 Jan 18; This revision of the 2012 guidelines focuses on early management in adults. Sponsoring Organizations: Surviving Sepsis Campaign, Society of Critical Care Medicine, and European Society of Intensive Care Medicine Target Population: Clinicians who care for adult patients with sepsis and septic shock in a hospital setting. Background and […]
Read MoreThe Institute for Safe Medicine Practices reviewed 12 months of FDA data and identified hundreds of cases of acute liver failure in patients taking direct-acting antivirals for hepatitis C. In October, the FDA announced that it was adding a boxed warning to the labels of direct-acting antivirals after identifying 24 cases of hepatitis B reactivation. […]
Read MoreAuthors: Michael J. Murray et al Crit Care Med. 2016;44(11):2079-2103. Objective: To update the 2002 version of “Clinical practice guidelines for sustained neuromuscular blockade in the adult critically ill patient.” Design: A Task Force comprising 17 members of the Society of Critical Medicine with particular expertise in the use of neuromuscular-blocking agents; a Grading of Recommendations Assessment, Development, […]
Read MoreFor patients with severe, chronic back and leg pain, a new high-frequency spinal cord stimulation (SCS) technique provides superior clinical outcomes, compared to conventional low-frequency SCS, reports a clinical trial in the November issue of Neurosurgery. The new ‘HF10’ technique offers lasting reductions in back and leg pain after other treatments have failed, according to […]
Read MoreThe implementation of an evidence-based, multimodal pain regimen after Roux-en-Y gastric bypass (LRYGB) was associated with a significant decrease in narcotic requirements as well as maximum postoperative pain scores, according to a study presented here on November 1 at Obesity Week 2016, the Annual Meetings of the American Society for Metabolic & Bariatric Surgery (ASMBS) […]
Read MoreAuthors: Magdalena Serra et al BMC Anesthesiol. 2016;16(78) Background: The use of elastomeric devices for ambulatory intravenous pain treatment in Major Ambulatory Surgery (MAS) has been described to improve postoperative pain management. The objective of the study was to describe the first 3 years experience of the use of elastomeric devices for ambulatory intravenous pain treatment in […]
Read MoreA Randomized Controlled Trial Authors: Wenwen Zhai et al BMC Anesthesiol. 2016;16(80) Background: Ultrasound guidance has reduced the amount of local anesthetics to achieve a successful block. Previous studies of the relationship between the volume or concentration of local anesthetics and the effects of the block were based on relatively high doses of local anesthetics. We tested […]
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