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Results of a Predefined Secondary Analysis of the VISION Study Authors: T. E. F. Abbott et al Br J Anaesth. 2016;117(2):172-181. Background: Increased baseline heart rate is associated with cardiovascular risk and all-cause mortality in the general population. We hypothesized that elevated preoperative heart rate increases the risk of myocardial injury after non-cardiac surgery (MINS). Methods: We performed […]
Read MoreAuthors: Hitoshi Sato et al BMC Anesthesiol. 2016;16(47) Background: Compared to conventional tidal volume ventilation, low tidal-volume ventilation reduces mortality in cased of acute respiratory distress syndrome. The aim of the present study is to determine whether low tidal-volume ventilation reduces the production of inflammatory mediators in the lungs and improves physiological status during hepatic surgery. Methods: We […]
Read MoreA Double-blind Phase III Study of Haemostatic Therapy Authors: N. Rahe-Meyer et al Br J Anaesth. 2016;117(1):41-51. Background: Single-dose human fibrinogen concentrate (FCH) might have haemostatic benefits in complex cardiovascular surgery. Methods: Patients undergoing elective aortic surgery requiring cardiopulmonary bypass were randomly assigned to receive FCH or placebo. Study medication was administered to patients with a 5 min […]
Read MoreA Systematic Review With Trial Sequential Analysis Authors: S. Weibel et al Br J Anaesth. 2016;116(6):770-783. Background: Improvement of postoperative pain and other perioperative outcomes remain a significant challenge and a matter of debate among perioperative clinicians. This systematic review aims to evaluate the effects of perioperative i.v. lidocaine infusion on postoperative pain and recovery in patients […]
Read MoreClinicians are spending nearly two hours working on electronic health records (EHRs) for every hour they spend with a patient—a trend that may contribute to burnout, according to a new study. Physicians in ambulatory care practices, such as GI, family medicine, cardiology, internal medicine and orthopedics, report spending an extra two hours of in-office time […]
Read MoreDelivering continuous positive airway pressure (CPAP) with novel nasal PAP mask assembly is an effective technique for improving safety in patients receiving an interscalene block and sedation for shoulder arthroscopy, new research suggests. Some people may be given a sedative after a regional peripheral nerve block. Desaturation commonly occurs in patients receiving moderate to deep […]
Read MoreMore than one-third of children require at least one form of PACU analgesic after outpatient surgery, according to a recent study. The trial also unearthed several predictors of PACU opioid requirements, the most notable of which was a history of obstructive sleep apnea (OSA). “The biggest challenge with respect to treating children in the ambulatory […]
Read MoreThe FDA has approved an IV bag presentation of acetaminophen (Ofirmev) injection, giving health care providers another delivery option, Mallinckrodt Pharmaceuticals announced. Acetaminophen injection is the first—and currently the only—FDA-approved IV formulation of the drug in the United States, according to Mallinckrodt. It is indicated for the management of mild to moderate pain, management of […]
Read MoreA pilot study has found that patients randomly assigned to cricoid pressure or sham treatment showed no difference in time to lowest peripheral capillary oxygen saturation (SpO2) or lowest SpO2 during anesthesia induction with planned endotracheal intubation. “Application of 30 N of cricoid pressure was not associated with a significant difference in time to reach lowest […]
Read MoreUpdate of guidelines recommends FDA-approved treatments and cautions against the use of opioids. The American Diabetes Association (ADA) has updated its guidelines on the management of diabetic peripheral neuropathy (DPN) in patients with diabetes. The guidelines,1 which were last updated in 2005, recommend pregabalin (Lyrica) or duloxetine (Cymbalta, generic) as first-line medication therapies for managing symptoms of DPN. […]
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