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There are fewer Antiplatelet Trialists Collaboration (APTC) events with celecoxib than with naproxen or ibuprofen, and higher rates of gastrointestinal adverse events with naproxen or ibuprofen than with celecoxib, according to results of a post-marketing cardiovascular safety analysis of celecoxib, presented at the 2016 Annual Meeting of the American Heart Association (AHA). When the cyclooxygenase […]
Read MoreAuthors: Ilona Razlevice eet al BMC Anesthesiol. 2016;16(107) Background: Cerebral oxygen saturation (rSO2c) decrease from baseline greater than 20 % during infant cardiac surgery was associated with postoperative neurologic changes and neurodevelopmental impairment at 1 year of age. So far, there is no sufficient evidence to support the routine monitoring of rSO2c during general surgical procedures in […]
Read MorePatients with implanted devices for spinal cord stimulation (SCS) for whom paresthesia-based stimulation has failed to relieve pain may have an “effective alternative” in subperception stimulation at 1 kHz, a recent pilot study suggests. The investigators conducted a prospective, randomized study (Neuromodulation 2016 May 17. [Epub ahead of print]) to apply the findings of a study […]
Read MoreTaking two common drugs—an over-the-counter proton pump inhibitor (PPI) and an antibiotic—together was associated with an increased risk for life-threatening arrhythmia (J Am Coll Cardiol 2016 Oct 10. New York researchers scanned data from two independent databases to investigate possible QT interval–prolonging drug–drug interactions: 1.8 million adverse event reports from the FDA’s Adverse Event Reporting System […]
Read MoreContrary to CDC data, ventilator-associated pneumonia (VAP) rates in hospital ICUs have not declined significantly since 2005, according to a new study from the University of Connecticut School of Medicine, in Farmington (JAMA 2016 Nov 11. [Epub ahead of print]). From 2005 to 2013, the study found that about 10% of critically ill patients placed on […]
Read MoreAuthors: Mack M and Holmes DR., Lancet 2016 Oct 31; A large randomized trial surprisingly demonstrates superior 5-year outcomes for coronary-artery bypass surgery in patients with left main coronary artery disease. For years, coronary-artery bypass grafting (CABG) has been the standard method for revascularization in patients with left main coronary artery disease. In NOBLE, a noninferiority study supported […]
Read MorePatients who use opioids before abdominal wall repair (AWR) have a greater need for opioids while in the hospital, and their stay may be longer than for patients who do not use the drugs before surgery, according to research presented at the Americas Hernia Society 2016 meeting. “We were beginning to see the impact of […]
Read MoreA novel predictive spinal cord stimulation (SCS) algorithm for chronic pain, presented at the 2016 Neural Interfaces Conference in Baltimore, was inspired by biological evolution. Akin to the neck of a giraffe becoming longer in order to reach leaves higher on a tree for eating, the algorithm relies on computational evolution to refine sets of […]
Read MoreStudy suggests factors other than pain may influence continued use. Patients who are prescribed opioids to manage their joint pain after total knee and total hip arthroplasty (TKA and THA) procedures may remain on opioids long term, well after they have ceased to experience improvements in their pain, according to collaborators at the University of […]
Read MoreWhen it comes to gauging patient satisfaction with anesthesia and perioperative care, operating rooms (ORs) are a bit too noisy and hospitals can be difficult to navigate. Researchers concluded that while patients are generally satisfied with their care, institutions should continually gauge their clients’ feelings in the hopes of improving the patient care experience. “Patient […]
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