-
-
Call more information
660-596-2224 -
Authors: Michael R. Mathis, M.D. et al Anesthesiology 2 2017, Vol.126, 249-259 Background: Assessment of need for intravascular volume resuscitation remains challenging for anesthesiologists. Dynamic waveform indices, including systolic and pulse pressure variation, are demonstrated as reliable measures of fluid responsiveness for mechanically ventilated patients. Despite widespread use, real-world reference distributions for systolic and pulse pressure variation […]
Read MoreAuthors: Andrew J. Toner, F.R.C.A. et al Anesthesiology 2 2017, Vol.126, 234-248. Background: Glucocorticoids are increasingly used perioperatively, principally to prevent nausea and vomiting. Safety concerns focus on the potential for hyperglycemia and increased infection. The authors hypothesized that glucocorticoids predispose to such adverse outcomes in a dose-dependent fashion after elective noncardiac surgery. Methods: The authors conducted […]
Read MoreAuthors: Colin F. Royse, M.B.B.S., M.D., F.A.N.Z.C.A. et al Anesthesiology 2 2017, Vol.126, 223-233. Background: Inflammation after cardiopulmonary bypass may contribute to postoperative delirium and cognitive dysfunction. The authors evaluated the effect of high-dose methylprednisolone to suppress inflammation on the incidence of delirium and postoperative quality of recovery after cardiac surgery. Methods: Five hundred fifty-five adults from […]
Read MoreAuthors: Robert D. Sanders, M.B.B.S., Ph.D., F.R.C.A. et al Anesthesiology 2 2017, Vol.126, 214-222. Background: The isolated forearm technique allows assessment of consciousness of the external world (connected consciousness) through a verbal command to move the hand (of a tourniquet-isolated arm) during intended general anesthesia. Previous isolated forearm technique data suggest that the incidence of connected consciousness […]
Read MoreAuthors: Glenn S. Murphy, M.D. et al Anesthesiology 10 2016, Vol.125, 611-614 BY the late 1980s, it was well recognized that undetected postoperative residual neuromuscular block (PRNB) was a common occurrence in most postanesthesia care units (PACUs).1–4 However, an editorial in 1989 noted that there was little, if any, objective evidence to validate the hypothesis that PRNB […]
Read MoreAuthors: Motov S et al., Ann Emerg Med 2016 Dec 16; Limiting the assessment of pain relief with ketorolac to 30–120 minutes after administration limits the conclusions we can draw from this study. To determine the optimal dose of ketorolac, investigators at a single U.S. emergency department conducted a randomized double-blind trial in 240 patients with moderate-to-severe […]
Read MoreAuthors: Upchurch CP et al., Ann Emerg Med 2017 Jan 69:24 An observational study suggests that these two agents are similarly safe but sends a possibly worrisome signal. Several studies have sought — and failed to find — evidence that etomidate is bad for patients due to the adrenal suppression it is known to cause (NEJM JW […]
Read MoreAuthors: Driver BE et al., Ann Emerg Med 2017 Jan 69:1 High-flow oxygen through a nonrebreather mask is noninferior to bag-valve-mask for preoxygenation. Preoxygenation is a key step in rapid sequence intubation and involves allowing the patient to breath spontaneously with supplemental oxygen. The classic method, thought to achieve the highest alveolar oxygen concentration, is to use […]
Read MoreAuthors: Lukas Lannemyr, M.D. et al Anesthesiology 2 2017, Vol.126, 205-213. Background: Acute kidney injury is a common complication after cardiac surgery with cardiopulmonary bypass. The authors evaluated the effects of normothermic cardiopulmonary bypass on renal blood flow, glomerular filtration rate, renal oxygen consumption, and renal oxygen supply/demand relationship, i.e., renal oxygenation (primary outcome) in patients undergoing cardiac […]
Read More