Authors: Sumihisa Orita, MD, PhD et al Spine. 2016;41(15):1224-1231. Study Design. A cross-sectional study of 1804 consecutive patients. Objective. The aim of this study was to investigate the prevalence of pathological pain and its distribution features in patients with chronic lumbar spinal disorders. Summary of Background Data. Clinical spinal disorders can involve pathological neuropathic pain (NeP) as well as […]
Read MoreAuthors: O. Corli; I. Floriani et al Ann Oncol. 2016;27(6):1107-1115. Background: Guidelines tend to consider morphine and morphine-like opioids comparable and interchangeable in the treatment of chronic cancer pain, but individual responses can vary. This study compared the analgesic efficacy, changes of therapy and safety profile over time of four strong opioids given for cancer pain. Patient […]
Read MoreAuthors: Marc Labetoulle et al Br J Ophthalmol. 2016;100(7):976-985. Background/aims To compare the efficacy and safety of intracameral (IC) administration at the beginning of cataract surgery, of Mydrane, a standardised ophthalmic combination of tropicamide 0.02%, phenylephrine 0.31% and lidocaine 1%, to a standard topical regimen. Methods In this international phase III, prospective, randomised study, the selected eye of […]
Read MoreAuthors: Nikhil R Sahni et al BMJ. 2016;354(i3571) Objective To measure the association between a surgeon’s degree of specialization in a specific procedure and patient mortality. Design Retrospective analysis of Medicare data. Setting US patients aged 66 or older enrolled in traditional fee for service Medicare. Participants 25 152 US surgeons who performed one of eight procedures (carotid endarterectomy, coronary […]
Read MoreFouad Ghazi Souki, MD Assistant Professor Shweta Rahul Yemul-Golhar, MD Transplant Anesthesia Fellow Yosaf Zeyed, MD Transplant Anesthesia Fellow Ernesto A. Pretto Jr, MD, MPH Professor Department of Anesthesiology Division of Transplantation University of Miami/Jackson Health System Miami, Florida The authors reported no relevant financial disclosures. Case Description A 46-year-old woman presented for incisional hernia […]
Read MoreSufentanil sublingual tablets effectively control acute pain after outpatient abdominal surgery. Results from a multicenter, randomized, placebo-controlled study suggest that 30-mg tablets are “efficacious and well tolerated across a variety of ambulatory surgery procedures for the management of moderate to severe acute postoperative pain,” said Pamela Palmer, MD, PhD, chief medical officer and co-founder of […]
Read MoreRoughly 40% of women receiving intrathecal opioids for cesarean delivery experience hypercapnia, according to a study presented at the 2016 annual meeting of the Society for Obstetric Anesthesia and Perinatology. The researchers said the condition is underdetected in the obstetric population, as per the current guidelines of the American Society of Anesthesiologists (ASA). “Women with […]
Read MoreAnesthesia & Analgesia: December 2016 – Volume 123 – Issue 6 – p 1567–1573 AUTHORS: Dexter, Franklin MD, PhD et al BACKGROUND: Anesthesiologists providing care during off hours (ie, weekends or holidays, or cases started during the evening or late afternoon) are more likely to care for patients at greater risk of sustaining major adverse […]
Read MoreAnesthesia & Analgesia: September 2016 AUTHORS: Choi, Eun Kyung MD, PhD et al BACKGROUND: Superoxide, nitric oxide (NO), and peroxynitrite are important mediators in the pathogenesis of ischemia-reperfusion (I/R) injury. We tested the renoprotective effects of allopurinol (ALP), a xanthine oxidase inhibitor, N-nitro-L-arginine methyl ester (L-NAME), and 5,10,15,20-tetrakis (N-methyl-4-pyridyl) porphyrinato iron (III) (FeTMPyP) by selective […]
Read MoreAnesthesia & Analgesia: December 2016 – Volume 123 – Issue 6 – p 1471–1479 AUTHORS: Belcher, Allan W. DO et al BACKGROUND: Opioids can contribute to postoperative desaturation. Short-acting opioids, titrated to need, may cause less desaturation than longer-acting opioids. We thus tested the primary hypothesis that long-acting patient-controlled intravenous opioids are associated with more […]
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