Month: December 2016

Uncategorized Published - 16 December, 2016    By - Dr Clemens
Transcutaneous PCO2 Monitoring in Newborn Infants During General Anesthesia Is Technically Feasible

Anesthesia & Analgesia: October 2016 – Volume 123 – Issue 4 – p 1004–1007 AUTHORS: Karlsson, Victoria RN, MMSc et al BACKGROUND: Transcutaneous (TC) measurement of PCO2 (TC PCO2) is a well-established method to monitor assisted ventilation in neonatal intensive care, but its use in the operating room is limited, and the data regarding its performance […]

Read More
Uncategorized Published - 16 December, 2016    By - Dr Clemens
Patient-Controlled Analgesia Plus Background Opioid Infusion for Postoperative Pain in Children: A Systematic Review and Meta-Analysis of Randomized Trials

Anesthesia & Analgesia: October 2016 – Volume 123 – Issue 4 – p 991–1003 AUTHORS: Hayes, Jason MD et al BACKGROUND: Bolus administration of opioids via a patient-controlled analgesia (PCA) device is widely used in the postoperative pediatric population. PCA devices have been shown to provide superior analgesia and greater patient satisfaction compared with intermittent […]

Read More
Uncategorized Published - 16 December, 2016    By - Dr Clemens
FDA Issues Warning on Use of Sedation Drugs in Young Children, Pregnant Women

Repeated use of general anesthetic and sedation drugs — or use for longer than 3 hours — in children under age 3 years and in pregnant women in their third trimester could adversely affect child brain development, the FDA warned on Wednesday. The agency cited animal data showing that early, lengthy exposure to these drugs […]

Read More
Uncategorized Published - 15 December, 2016    By - Dr Clemens
Risk Factors for Unintended Dural Puncture in Obstetric Patients: A Retrospective Cohort Study

Anesthesia & Analgesia: October 2016 – Volume 123 – Issue 4 – p 972–976 AUTHORS: Orbach-Zinger, Sharon MD et al BACKGROUND: Unintended dural puncture (UDP) is one of the main risks of epidural analgesia, with a reported incidence of approximately 1.5% among the obstetric population. UDP is associated with maternal adverse outcomes, with the most […]

Read More
Uncategorized Published - 15 December, 2016    By - Dr Clemens
The Effect of Combined Spinal–Epidural Versus Epidural Analgesia in Laboring Women on Nonreassuring Fetal Heart Rate Tracings: Systematic Review and Meta-analysis

Anesthesia & Analgesia: October 2016 – Volume 123 – Issue 4 – p 955–964 AUTHORS: Hattler, Judith MD et al BACKGROUND: Combined spinal–epidural labor analgesia has gained popularity, but it is unclear whether this technique is associated with a higher incidence of nonreassuring fetal heart rate (FHR) tracings compared with epidural analgesia. Our meta-analysis aimed […]

Read More
Uncategorized Published - 15 December, 2016    By - Dr Clemens
Response Patterns to the Electric Stimulation of Epidural Catheters in Pregnant Women: A Randomized Controlled Trial of Uniport Versus Multiport Catheters

Anesthesia & Analgesia: October 2016 – Volume 123 – Issue 4 – p 950–954 AUTHORS: Patel, Ruchira MBBS et al BACKGROUND: The transcatheter electric stimulation test (Tsui test) can be performed at the bedside to confirm the correct placement of a wire-reinforced epidural catheter within the epidural space. The most commonly observed motor response with […]

Read More
Uncategorized Published - 15 December, 2016    By - Dr Clemens
Prevention of Spinal Anesthesia-Induced Hypotension During Cesarean Delivery by 5-Hydroxytryptamine-3 Receptor Antagonists: A Systematic Review and Meta-analysis and Meta-regression

Anesthesia & Analgesia: October 2016 – Volume 123 – Issue 4 – p 977–988 AUTHORS: Heesen, Michael MD, PhD et al BACKGROUND: Hypotension remains a frequent complication of spinal anesthesia, increasing the risk of nausea and vomiting, altered mental status, and aspiration. The aim of this systematic review and meta-analysis was to determine whether 5-hydroxytryptamine3 […]

Read More
Uncategorized Published - 15 December, 2016    By - Dr Clemens
Implementation of Programmed Intermittent Epidural Bolus for the Maintenance of Labor Analgesia

Anesthesia & Analgesia: October 2016 – Volume 123 – Issue 4 – p 965–971 AUTHORS: Carvalho, Brendan MBBCh, FRCA, MDCH et al Programmed intermittent epidural bolus (PIEB) is an exciting new technology that has the potential to improve the maintenance of epidural labor analgesia. PIEB compared with a continuous epidural infusion (CEI) has the potential […]

Read More
Uncategorized Published - 14 December, 2016    By - Dr Clemens
The Amount of Fluid Given During Surgery That Leaks Into the Interstitium Correlates With Infused Fluid Volume and Varies Widely Between Patients

Anesthesia & Analgesia: October 2016 – Volume 123 – Issue 4 – p 925–932 AUTHORS: Nishimura, Akiko DDS, PhD et al BACKGROUND: The revised Starling law suggests that intravenously infused fluid may leak into the interstitium and not remain in the intravascular space. This hypothesis is supported by clinical findings that postoperative weight gain is […]

Read More
Uncategorized Published - 14 December, 2016    By - Dr Clemens
Impact of an Analgesia-Based Sedation Protocol on Mechanically Ventilated Patients in a Medical Intensive Care Unit

Anesthesia & Analgesia: October 2016 – Volume 123 – Issue 4 – p 903–909 AUTHORS: Faust, Andrew C. PharmD, BCPS et al BACKGROUND: Recent attention to adverse effects of intensive care unit (ICU) sedation has led to the use of strategies that target a “lighter” depth of sedation. Among these strategies are “analgosedation” protocols, which […]

Read More