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Read MoreAuthors: Göran Hedenstierna, M.D., Ph.D. et al Anesthesiology 12 2016, Vol.125, 1079-1082. SEVERAL clinical trials on protective ventilation during anesthesia and postoperative pulmonary complications have been performed during the past years and assumed to be suitable as guidelines for clinical treatment.1–8 Comprehensive reviews and meta-analysis have also been performed.9,10 Why then do these studies differ in their recommendations? […]
Read MoreMedicine: November 2016 – Volume 95 – Issue 48 – p e5074 Authors: Zheng, Jun MD et al Abstract: This study aims to evaluate the effect of naloxone on intravenous fentanyl patient-controlled analgesia after laparoscopic cholecystectomy under total intravenous anesthesia. A total of 90 patients, who underwent intravenous fentanyl patient-controlled analgesia after laparoscopic cholecystectomy under […]
Read MoreAuthors: Åse Lodenius, M.D., D.E.S.A.et al Anesthesiology 10 2016, Vol.125, 700-715 Background: In contrast to general anesthetics such as propofol, dexmedetomidine when used for sedation has been put forward as a drug with minimal effects on respiration. To obtain a more comprehensive understanding of the regulation of breathing during sedation with dexmedetomidine, the authors compared ventilatory responses […]
Read MoreOpioids are widely used in the United States to manage moderate to severe acute postoperative pain, but adverse events, including respiratory depression and gastrointestinal dysfunction, can limit the dosing required for analgesic efficacy. Oliceridine—a novel mu-receptor G protein pathway selective modulator—may provide effective, rapid analgesia and reduce typical adverse effects, according to two recent Phase […]
Read MoreAnesthesia & Analgesia: October 2016 – Volume 123 – Issue 4 – p 836–843 Authors: Sivanesan, Eellan MD et al Despite their association with multiple adverse effects, opioid prescription continues to increase. Opioid-induced hallucination is an uncommon yet significant adverse effect of opioid treatment. The practitioner may encounter patient reluctance to volunteer the occurrence of […]
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