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Anesthesia & Analgesia: August 2016 – Volume 123 – Issue 2 – p 299–308 AUTHORS: Liou, Jing-Yang MD et al BACKGROUND: Selecting an effective dose of sedative drugs in combined upper and lower gastrointestinal endoscopy is complicated by varying degrees of pain stimulation. We tested the ability of 5 response surface models to predict depth […]
Read MoreAuthors: Walley AY and Green TC. Published in Ann Intern Med 2016 Jun 28; Coprescribing naloxone was associated with fewer opioid-related emergency room visits. Many communities that use targeted distribution of the short-acting opioid antagonist naloxone to reverse unintentional opioid overdoses have seen declines in community-level opioid overdose–related mortality. In this observational study from six “safety net” […]
Read MoreBy Lynn R. Webster, MD A Medpage Today article titled “Opioid Crisis: Scrap Pain as 5th Vital Sign?” lays out similar flawed arguments touted by Physicians for Responsible Opioid Prescribing (PROP). The American Medical Association was petitioned by its Illinois delegates to remove pain’s fifth-vital-sign status. What are these flawed arguments? One is to falsely equate the […]
Read MoreMalpractice claims are a dreaded but rare fact of the practice of medicine—but not so rare if you’ve already been sued, researchers have found. A recent study suggests that a small share of physicians account for the majority of malpractice suits in the United States. How small? Roughly 1% of all doctors were involved in […]
Read MoreOpioids as a treatment for chronic pain have exposed the holes in our country’s health care system in an unparalleled fashion. Now, a new guideline issued by the Centers for Disease Control and Prevention (CDC) discourages the use of opioids in treating chronic pain, excluding cancer and end-of-life care (MMWR Recomm Rep 2016;65:1-49). The CDC touts […]
Read MoreAnesthesia & Analgesia: August 2016 – Volume 123 – Issue 2 – p 420–429 AUTHORS: Willems, Ariane MD, MSci Biomed, PhD et al BACKGROUND: Children undergoing cardiac surgery are frequently exposed to red blood cell (RBC) transfusions mainly in the case of hemorrhage or low oxygen transport. However, in this population, RBCs are sometimes added […]
Read MoreAnesthesia & Analgesia: August 2016 – Volume 123 – Issue 2 – p 363–370 AUTHORS: Bang, Ji-Yeon MD, PhD et al BACKGROUND: Acute kidney injury (AKI) is a primary cause of morbidity and mortality after major abdominal surgery; however, little is known about the effect of anesthetics on the development of AKI after colorectal surgery. […]
Read MoreAuthors: Glenn S. Murphy, M.D. etal Anesthesiology 10 2016, Vol.125, 611-614 BY the late 1980s, it was well recognized that undetected postoperative residual neuromuscular block (PRNB) was a common occurrence in most postanesthesia care units (PACUs).1–4 However, an editorial in 1989 noted that there was little, if any, objective evidence to validate the hypothesis that PRNB […]
Read MoreAuthors: M. Ruth Graham, M.D., F.R.C.P.(C). et al Anesthesiology 10 2016, Vol.125, 667-677 Background: Animal studies demonstrate general anesthetic (GA) toxicity in the developing brain. Clinical reports raise concern, but the risk of GA exposure to neurodevelopment in children remains uncertain. Methods: The authors undertook a retrospective matched cohort study comparing children less than 4 yr of age […]
Read MoreAuthors: Catherine M. Bulka, M.P.H. et al Anesthesiology 10 2016, Vol.125, 647-655. Background: Residual postoperative paralysis from nondepolarizing neuromuscular blocking agents (NMBAs) is a known problem. This paralysis has been associated with impaired respiratory function, but the clinical significance remains unclear. The aims of this analysis were two-fold: (1) to investigate if intermediate-acting NMBA use […]
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