Month: September 2016

Uncategorized Published - 2 September, 2016    By - Dr Clemens
Oxygen Therapy: When Is Too Much Too Much?

Commentary: A Multicenter, Randomized, Controlled Phase IIb Trial of Avoidance of Hyperoxemia during Cardiopulmonary Bypass Authors: Shahzad Shaefi, M.D. et al Anesthesiology 9 2016, Vol.125, 449-450. THERE are approximately 300,000 cardiac surgical procedures annually utilizing cardiopulmonary bypass (CPB) in the United States.  The delivery of oxygen has been a cornerstone of anesthesia practice, with titration of oxygen therapy to […]

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Uncategorized Published - 1 September, 2016    By - Dr Clemens
Which Anesthesia Regimen Is Best to Reduce Morbidity and Mortality in Lung Surgery?: A Multicenter Randomized Controlled Trial

Authors: Beatrice Beck-Schimmer, M.D. et al Anesthesiology 8 2016, Vol.125, 313-321. Background: One-lung ventilation during thoracic surgery is associated with hypoxia–reoxygenation injury in the deflated and subsequently reventilated lung. Numerous studies have reported volatile anesthesia–induced attenuation of inflammatory responses in such scenarios. If the effect also extends to clinical outcome is yet undetermined. We hypothesized that volatile […]

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Uncategorized Published - 1 September, 2016    By - Dr Clemens
Changes in Brain Resting-state Functional Connectivity Associated with Peripheral Nerve Block: A Pilot Study

Authors: M. Stephen Melton, M.D. et al Anesthesiology 8 2016, Vol.125, 368-377 Background: Limited information exists on the effects of temporary functional deafferentation (TFD) on brain activity after peripheral nerve block (PNB) in healthy humans. Increasingly, resting-state functional connectivity (RSFC) is being used to study brain activity and organization. The purpose of this study was to test […]

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Uncategorized Published - 1 September, 2016    By - Dr Clemens
Reduced Cancer Risk, Improved Survival With Neuraxial Anesthesia

Neuraxial anesthesia (NA) appears to be associated with improved overall survival (OS) in patients undergoing surgery for tumor resection, particularly in those with colorectal cancer. According to a recent meta-analysis published in Oncotarget(2016;7:15262-15273), the authors identified a correlation between the use of NA and reduced risk for cancer recurrence. The authors found significantly improved OS and […]

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Uncategorized Published - 1 September, 2016    By - Dr Clemens
Are You Conservative or Liberal?

Fluid Management Strategy for Thoracic Surgery: The optimal range of fluid administration in patients undergoing lung resection surgery has been a controversial topic in anesthesia. There are hazards at both ends of the spectrum: Liberal over-hydration can lead to fluid-induced lung injury, while conservative fluid-management strategies have a risk for organ ischemia. According to a […]

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Uncategorized Published - 1 September, 2016    By - Dr Clemens
Providing Value-Based Regional Anesthesia: It’s a Matter of Angles

The value of the services that anesthesiologists provide is being examined more closely than ever. Indeed, determining the true value of regional anesthesia can only be done within the context of its many costs, most of which are not monetary. “‘Value’ is the name of the game in medicine these days,” said Brian E. Harrington, […]

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