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Anesthesia & Analgesia: July 26, 2016 Authors: Petersen, Christian Leth PhD et al BACKGROUND: Recent research and advances in the automation of anesthesia are driving the need to better understand electroencephalogram (EEG)-based anesthesia end points and to test the performance of anesthesia monitors. This effort is currently limited by the need to collect raw EEG […]
Read MoreAnesthesia & Analgesia: July 26, 2016 AUTHORS: Karlsson, Victoria RN, MMSc BACKGROUND: Transcutaneous (TC) measurement of PCO2 (TC PCO2) is a well-established method to monitor assisted ventilation in neonatal intensive care, but its use in the operating room is limited, and the data regarding its performance during general anesthesia of the newborn are lacking. The […]
Read MoreAnesthesia & Analgesia: July 26, 2016 AUTHORS: Carvalho, Brendan MBBCh, FRCA, MDCH et al Programmed intermittent epidural bolus (PIEB) is an exciting new technology that has the potential to improve the maintenance of epidural labor analgesia. PIEB compared with a continuous epidural infusion (CEI) has the potential advantage of greater spread within the epidural space […]
Read MoreAnesthesia & Analgesia: July 22, 2016 AUTHORS: Kwon, Min-Ji BS et al BACKGROUND: Placing the patient in the prone position frequently is required for some surgical procedures. If cardiac arrest occurs and the patient cannot be safely turned supine, cardiopulmonary resuscitation (CPR) may need to be performed with the patient in the prone position. Although […]
Read MoreAnesthesiologists who use perioperative clonidine in the hope of reducing acute postoperative pain or opioid consumption need to reconsider their efforts. According to a randomized controlled trial at the Cleveland Clinic, in Ohio—the largest such trial ever—researchers found that the drug has neither of these perceived benefits, and its use may come at the expense […]
Read MoreAnesthesia & Analgesia: September 2016 – Volume 123 – Issue 3 – p 547–550 AUTHORS: Sentissi, Kinza MD et al In this prospective observational study, conducted at an academic medical center, we evaluated the feasibility of performing a basic transesophageal echocardiography (TEE) examination using endoscopic ultrasound (EUS) technology to determine what cardiac structures could be […]
Read MoreAnesthesia & Analgesia: September 2016 – Volume 123 – Issue 3 – p 535–546 AUTHORS: Mitrophanov, Alexander Y. PhD et al BACKGROUND: The use of prothrombin complex concentrates in trauma- and surgery-induced coagulopathy is complicated by the possibility of thromboembolic events. To explore the effects of these agents on thrombin generation (TG), we investigated combinations […]
Read MoreAnesthesia & Analgesia: September 2016 – Volume 123 – Issue 3 – p 570–577 AUTHORS: Fabbro, Michael II DO et al BACKGROUND: The inflated costs and documented deleterious effects of excess perioperative transfusion have led to the investigation of targeted coagulation factor replacement strategies. One particular coagulation factor of interest is factor I (fibrinogen). Hypofibrinogenemia […]
Read MoreA study published in PLOS ONE shows that symptoms of chronic fatigue syndrome can be provoked by imposing a mild to moderate strain to the muscles and nerves. The study included 80 individuals, 60 with CFS and 20 without CFS, who reported their levels of fatigue, body pain, lightheadedness, concentration difficulties, and headache every 5 […]
Read MoreHi. I’m Art Caplan, PhD from the Division of Medical Ethics and the New York University (NYU) Langone Medical Center. A former student of mine, who is now in medical school, asked me a question that comes up again and again. I have not talked about it here, but I think it does merit some […]
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