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Anesthesiology 4 2016, Vol.124, 878-884. Authors: Liping Han, M.D., M.Sc. et al Background: Propofol (2,6-diisopropylphenol) is one of the most frequently used anesthetic agents. One of the main side effects of propofol is to reduce blood pressure, which is thought to occur by inhibiting the release of catecholamines from sympathetic neurons. Here, the authors hypothesized that propofol-induced […]
Read MoreAnesthesiology 4 2016, Vol.124, 785-794. Authors: Derryn A. Gargiulo, M.Pharm.Clin., Reg.Pharm.N.Z. et al Background: The aseptic techniques of anesthesiologists in the preparation and administration of injected medications have not been extensively investigated, but emerging data demonstrate that inadvertent lapses in aseptic technique may be an important contributor to surgical site and other postoperative infections. Methods: A prospective, […]
Read MoreAnesthesiology 4 2016, Vol.124, 837-845. Authors: Karim S. Ladha, M.D., M.Sc. et al Background: Practice guidelines for perioperative pain management recommend that multimodal analgesic therapy should be used for all postsurgical patients. However, the proportion of patients who actually receive this evidence-based approach is unknown. The objective of this study was to describe hospital-level patterns in […]
Read MoreAuthor: Laszlo Vutskits, M.D., Ph.D. Anesthesiology 4 2016, Vol.124, 758-760. ADVERSE experiences during the perinatal period are associated with altered pain sensitivity and long-term behavioral sequels, including significant emotional problems during childhood and major psychotic episodes, anxiety, depression, and suicides in adolescence or adulthood.1 Exposure to painful stimuli is one major cause of these harmful incidents, especially […]
Read MoreAuthors: Allan F. Simpao, M.D., M.B.I.; Jorge A. Gálvez, M.D. Anesthesiology 4 2016, Vol.124, 750-751. THE pulse oximeter has become a virtually indispensable monitor for measuring a patient’s peripheral capillary oxygen saturation (Spo2) accurately and reliably in a continuous, noninvasive fashion.1 Despite its ubiquitous use as a detector of hypoxemia, pulse oximetry has limited utility to herald an […]
Read MoreAnesthesiology 4 2016, Vol.124, 804-814. Authors: Kyle R. Kirkham, M.D. et al Background: Increasing attention has been focused on low-value healthcare services. Through Choosing Wisely campaigns, routine laboratory testing before low-risk surgery has been discouraged in the absence of clinical indications. The authors investigated rates, determinants, and institutional variation in laboratory testing before low-risk procedures. Methods: Patients who […]
Read MoreAnesthesiology 4 2016, Vol.124, 826-836. Authors: Alain Deschamps, Ph.D., M.D. et al Background: Cerebral oxygen desaturation during cardiac surgery has been associated with adverse perioperative outcomes. Before a large multicenter randomized controlled trial (RCT) on the impact of preventing desaturations on perioperative outcomes, the authors undertook a randomized prospective, parallel-arm, multicenter feasibility RCT to determine whether an […]
Read MoreAnesthesiology 4 2016, Vol.124, 899-907. Authors: Hannah Wunsch, M.D., M.Sc. et al Background: Use of intensive care after major surgical procedures and whether routinely admitting patients to intensive care units (ICUs) improve outcomes or increase costs is unknown. Methods: The authors examined frequency of admission to an ICU during the hospital stay for Medicare beneficiaries undergoing selected […]
Read MoreAuthors: Spoletini G et al., JAMA 2016 Mar 15; High-flow oxygen and noninvasive positive pressure ventilation lowered reintubation rates in selected patient populations. During the past few years, interest has grown in using high-flow oxygen (HFO) and noninvasive positive pressure ventilation (NPPV) in lieu of intubation and mechanical ventilation (NEJM JW Gen Med Aug 1 2015 and JAMA 2015; 313:2331 […]
Read MoreA&A Case Reports: 15 February 2016 – Volume 6 – Issue 4 – p 88–89 Authors: Brown, Sara MD et al General anesthesia was administered in an 18-year-old man for removal of hardware from his right knee using a King Laryngeal Tube supraglottic airway. An hour after extubation, he reported inability to swallow with no […]
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