Month: March 2016

Uncategorized Published - 10 March, 2016    By - Dr Clemens
Increased Intraoperative Fluid Administration Is Associated with Severe Primary Graft Dysfunction After Lung Transplantation

Anesthesia & Analgesia: January 2016 AUTHORS: Geube, Mariya A. MD et al BACKGROUND: Severe primary graft dysfunction (PGD) is a major cause of early morbidity and mortality in patients after lung transplantation. The etiology and pathophysiology of PGD is not fully characterized and whether intraoperative fluid administration increases the risk for PGD remains unclear from […]

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Uncategorized Published - 9 March, 2016    By - Dr Clemens
Bradycardia as an Early Warning Sign for Cardiac Arrest During Routine Laparoscopic Surgery

Authors: Jonathan Yong et al Int J Qual Health Care. 2015;27(6):472-477. Objectives: The aim of this study was to identify clinical patterns of occurrence, management and outcomes surrounding cardiac arrest during laparoscopic surgery using the Australian Incident Monitoring Study (AIMS) database to guide possible prevention and treatment. Setting: The AIMS database includes incident reports from participating clinicians from […]

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Uncategorized Published - 9 March, 2016    By - Dr Clemens
The Feasibility of a Completely Automated Total IV Anesthesia Drug Delivery System for Cardiac Surgery.

Anesthesia & Analgesia: January 2016 AUTHORS: Zaouter, Cedrick MD et al BACKGROUND: In this pilot study, we tested a novel automatic anesthesia system for closed-loop administration of IV anesthesia drugs for cardiac surgical procedures with cardiopulmonary bypass. This anesthesia drug delivery robot integrates all 3 components of general anesthesia: hypnosis, analgesia, and muscle relaxation. METHODS: […]

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Uncategorized Published - 9 March, 2016    By - Dr Clemens
Anesthesia and Cognitive Decline: No Link?

There is no significant link between exposure to general anesthesia and the development of mild cognitive impairment (MCI) in individuals aged 40 years and older, a large, comprehensive, population-based study shows. The potential link between exposure to surgical anesthesia, MCI, and dementia has been a matter of recent debate, with previous research contradicting the current […]

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Uncategorized Published - 9 March, 2016    By - Dr Clemens
Inflammation and Organ Failure Severely Affect Midazolam Clearance in Critically Ill Children.

Am J Respir Crit Care Med. 2016 Jan 21 AUTHORS: Vet NJ et al RATIONALE: Various in vitro, animal and limited human adult studies suggest a profound inhibitory effect of inflammation and disease on Cytochrome P450 3A (CYP3A)-mediated drug metabolism. Studies showing this relationship in critically ill patients are lacking, while clearance of many CYP3A drug […]

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Uncategorized Published - 9 March, 2016    By - Dr Clemens
Electrical Stimulation of the Trigeminal Ganglion and Intrathecal Drug Delivery Systems for the Management of Corneal Neuropathic Pain

Cornea. 2016 Apr;35(4):576-7. AUTHORS: Sayegh RR et al PURPOSE: This case study reports on 2 novel neuromodulatory approaches in the management of a particularly recalcitrant case of corneal neuropathic pain. METHODS: Report of a case RESULTS: : A 32-year-old woman presented with intractable bilateral dry eye-like symptoms and corneal neuropathic pain after undergoing laser in situ […]

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Uncategorized Published - 8 March, 2016    By - Dr Clemens
Gradient between dorsalis pedis and radial arterial blood pressures during sevoflurane anaesthesia: A self-control study in patients undergoing neurosurgery

Eur J Anaesthesiol. 2016 Feb;33(2):110-7 AUTHORS: Chen Y et al BACKGROUND: The dorsalis pedis artery (DPA) is a good alternative to the radial artery (RA) for invasive blood pressure monitoring when the upper limb is burned or injured, or if the RA is not available. Understanding the pattern of pressure difference between DPA and the commonly […]

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Uncategorized Published - 8 March, 2016    By - Dr Clemens
Dorsalis pedis arterial pressure is lower than noninvasive arm blood pressure in normotensive patients under sevoflurane anesthesia

Blood Press Monit. 2016 Feb;21(1):27-32 AUTHORS: Chen Y et al BACKGROUND: It is widely known that blood pressure (BP) in the lower extremity is higher than in the upper extremity. However, whether this phenomenon remains the same during general anesthesia is still unclear. This study aims to investigate the difference between invasive dorsalis pedis artery (DPA) […]

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Uncategorized Published - 8 March, 2016    By - Dr Clemens
Comparison of emergence after deep extubation using desflurane or desflurane with remifentanil in patients undergoing general anesthesia: a randomized trial

J Clin Anesth. 2016 Feb;28:19-25. doi: 10.1016/j.jclinane.2015.08.013. Epub 2015 Nov 11. AUTHORS: Kim MK et al STUDY OBJECTIVE: To compare recovery times and respiratory complications during emergence after deep extubation using either desflurane alone or a lower concentration of desflurane with remifentanil. DESIGN: Prospective randomized double-blind clinical trial. SETTING: Intraoperative. PATIENTS: A total of 62 patients […]

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Uncategorized Published - 8 March, 2016    By - Dr Clemens
Aprepitant for antiemesis after laparoscopic gynaecological surgery: A randomised controlled trial

Eur J Anaesthesiol. 2016 Feb;33(2):90-5 AUTHORS: Ham SY et al BACKGROUND: Ondansetron, a 5-HT3 receptor antagonist, and aprepitant, a neurokinin-1 receptor antagonist, block the emetic effect of serotonin and neurokinin, respectively. Aprepitant combined with ondansetron can be more effective for preventing emesis in patients at high risk of postoperative nausea and vomiting (PONV). OBJECTIVE: To investigate […]

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