Month: March 2016

Uncategorized Published - 21 March, 2016    By - Dr Clemens
The Effectiveness of Midazolam for Preventing Postoperative Nausea and Vomiting: A Systematic Review and Meta-Analysis

Anesthesia & Analgesia: March 2016 – Volume 122 – Issue 3 – p 664–676 AUTHORS: Ahn, Eun Jin MD et al BACKGROUND: Previous randomized controlled trials regarding the effectiveness of perioperative midazolam in preventing postoperative nausea and vomiting (PONV) have produced conflicting results. Consequently, the present systematic review was performed to assess the effect of […]

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Uncategorized Published - 21 March, 2016    By - Dr Clemens
2,3-Diphosphoglycerate Concentrations in Autologous Salvaged Versus Stored Red Blood Cells and in Surgical Patients After Transfusion

Anesthesia & Analgesia: March 2016 – Volume 122 – Issue 3 – p 616–623 AUTHORS: Scott, Andrew V. BS et al BACKGROUND: Stored red blood cells (RBCs) are deficient in 2,3-diphosphoglycerate (2,3-DPG), but it is unclear how autologous salvaged blood (ASB) compares with stored blood and how rapidly 2,3-DPG levels return to normal after transfusion. […]

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Uncategorized Published - 21 March, 2016    By - Dr Clemens
Variability of Automated Intraoperative ST Segment Values Predicts Postoperative Troponin Elevation

Anesthesia & Analgesia: March 2016 – Volume 122 – Issue 3 – p 608–615 AUTHORS: Maile, Michael D. MD, MS et al BACKGROUND: Intraoperative electrocardiographic monitoring is considered a standard of care. However, there are no evidence-based algorithms for using intraoperative ST segment data to identify patients at high risk for adverse perioperative cardiac events. […]

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Uncategorized Published - 21 March, 2016    By - Dr Clemens
First-Attempt Intubation Success of Video Laryngoscopy in Patients with Anticipated Difficult Direct Laryngoscopy: A Multicenter Randomized Controlled Trial Comparing the C-MAC D-Blade Versus the GlideScope in a Mixed Provider and Diverse Patient Population

Anesthesia & Analgesia: March 2016 – Volume 122 – Issue 3 – p 740–750 AUTHORS: Aziz, Michael F. MD et al BACKGROUND: Intubation success in patients with predicted difficult airways is improved by video laryngoscopy. In particular, acute-angle video laryngoscopes are now frequently chosen for endotracheal intubation in these patients. However, there is no evidence […]

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Uncategorized Published - 21 March, 2016    By - Dr Clemens
Saline Flush After Rocuronium Bolus Reduces Onset Time and Prolongs Duration of Effect: A Randomized Clinical Trial

Anesthesia & Analgesia: March 2016 – Volume 122 – Issue 3 – p 706–711 AUTHORS: Ishigaki, Sayaka MD et al BACKGROUND: Circulatory factors modify the onset time of neuromuscular-blocking drugs. Therefore, we hypothesized that infusion of a saline flush immediately after rocuronium administration would shorten the onset time without influencing the duration of the rocuronium […]

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Uncategorized Published - 18 March, 2016    By - Dr Clemens
Risk Factors Involved in Central-to-Radial Arterial Pressure Gradient During Cardiac Surgery

Anesthesia & Analgesia: March 2016 – Volume 122 – Issue 3 – p 624–632 AUTHORS: Fuda, Giuseppe MD et al BACKGROUND: A central-to-radial arterial pressure gradient may occur after cardiopulmonary bypass (CPB), which, in some patients, may last for a prolonged time after CPB. Whenever there is a pressure gradient, the radial artery pressure measure […]

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Uncategorized Published - 18 March, 2016    By - Dr Clemens
Active Warming Utilizing Combined IV Fluid and Forced-Air Warming Decreases Hypothermia and Improves Maternal Comfort During Cesarean Delivery: A Randomized Control Trial

Anesthesia & Analgesia: February 18, 2016 AUTHORS: Cobb, Benjamin MD et al BACKGROUND: The aim of this study was to apply both IV fluid and forced-air warming to decrease perioperative hypothermia in women undergoing cesarean delivery with spinal anesthesia. The authors hypothesize that combined-modality active warming (AW) would increase maternal temperature on arrival at the […]

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Uncategorized Published - 18 March, 2016    By - Dr Clemens
Estimated Maximal Safe Dosages of Tumescent Lidocaine

Anesthesia & Analgesia: February 18, 2016 AUTHORS: Klein, Jeffrey A. MD, MPH et al BACKGROUND: Tumescent lidocaine anesthesia consists of subcutaneous injection of relatively large volumes (up to 4 L or more) of dilute lidocaine (<=1 g/L) and epinephrine (<=1 mg/L). Although tumescent lidocaine anesthesia is used for an increasing variety of surgical procedures, the […]

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Uncategorized Published - 18 March, 2016    By - Dr Clemens
Angiotensin Axis Blocking Drugs In the Perioperative Period

  Alan Smeltz, MD Resident-CA 2 University of North Carolina Chapel Hill, North Carolina   Priya A. Kumar, MD Professor of Anesthesiology University of North Carolina Chapel Hill, North Carolina Introduction Drugs causing angiotensin axis blockade (AAB) include angiotensin-converting enzyme inhibitor (ACEI) and angiotensin receptor blocker (ARB) agents. Due to the current trend of an […]

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Uncategorized Published - 18 March, 2016    By - Dr Clemens
Lumbar Total Disc Replacement for Discogenic Low Back Pain

Two-Year Outcomes of the ActivL Multicenter Randomized Controlled IDE Clinical Trial Authors: Rolando Garcia Jr., MD, MPH et al Spine. 2015;40(24):1873-1881. Study Design. A prospective, multicenter, randomized, controlled, investigational device exemption (IDE) noninferiority trial. Objective. The aim of this study was to evaluate the comparative safety and effectiveness of lumbar total disc replacement (TDR) in the treatment of […]

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